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Atrial Fibrillation clinical trials

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NCT ID: NCT03645564 Terminated - Atrial Fibrillation Clinical Trials

Impact of the Information Follow-up Given to Patients on Their Disease Understanding and Therapeutic Adherence in Patients Under Direct Oral Anticoagulants and With Atrial Fibrillation in a Cardiology Department

RYTHM-UP AOD
Start date: October 16, 2018
Phase: N/A
Study type: Interventional

The primary objective of this study is to measure in patients addressed for Atrial Fibrillation (AF) in the Cardiology-Electrophysiology and Cardiac Stimulation Department of Bordeaux hospital, the impact of a specialized nurse consultation on their adherence level to direct oral anticoagulants treatments.

NCT ID: NCT03636100 Terminated - Atrial Fibrillation Clinical Trials

Release of Acetylcholine From the Ganglionated Plexus During the Thaw Phase of Cryoballon Pulmonary Vein Ablation (GP RESPONSE Study)

Start date: August 15, 2018
Phase:
Study type: Observational

Determine whether the presence of acetylcholine in the systemic circulation, correlates with the hypotensive response observed during the thaw phase of cryoballoon ablation.

NCT ID: NCT03589742 Terminated - Atrial Fibrillation Clinical Trials

Feasibility Study for Optically Guided Radiofrequency Ablation Catheter

NEOVIEW
Start date: June 24, 2017
Phase: N/A
Study type: Interventional

Clinical study intended to evaluate the feasibility of a new irrigated RF ablation catheter that allows the physiologist to perform a regular RF ablation procedure while it is being monitored through an imaging technique known as Optical Coherence Reflectometry (OCR). This technique is based upon the use of infrared light; it is innocuous for the human body and allows for the detection of the contact between the catheter tip with the tissue besides the lesion formation during the Radiofrequency (RF) application as the OCR technique is able to distinguish between ablated tissue and healthy tissue. Both features are able to provide a better control of the ablation procedure, which may become in a better clinical result in cardiac ablation procedures, especially in Atrial Fibrillation cases.

NCT ID: NCT03467633 Terminated - Clinical trials for Persistent Atrial Fibrillation

Atrial Fibrillation Trial to Evade Recurrence: effectS of Hiit Before electrO-Cardioversion for 3-weeKs

AFTERSHOCK
Start date: April 25, 2018
Phase: N/A
Study type: Interventional

This is a study looking at the feasibility of conducting a larger definitive research trial looking at the effectiveness of high intensity interval training in individuals who are scheduled for electro-cardioversion. Usual care for these participants is to go home and continue with their typical daily routine. The investigators will test whether participating in 3-weeks of thrice-weekly high intensity interval training before electro-cardioversion can lengthen the time to recurrence of atrial fibrillation after electro-cardioversion in these individuals. Participants will be asked to come to the University of Ottawa Heart Institute for a baseline visit at which fitness (cycle ergometer), body composition (weight, height, waist circumference and percentage body fat), heart rate variability and habitual exercise levels will be measured. Participants will then be randomized to either the exercise group or the usual care group. Those randomized to the usual care group will go home for 3-weeks and continue with their typical daily routine. Those randomized to the exercise group will return to the Heart Institute three times per week for 3-weeks to participate in a high intensity interval training program prior to their electro-cardioversion. All participants will be asked to measure daily heart rate and rhythm using the AliveCor system which is compatible with their Smartphones, for up to 12-months following their electro-cardioversion. All participants will be asked to return at 3-weeks (and prior to their electro-cardioversion) to measure fitness (cycle ergometer), body composition (weight, height, waist circumference and percentage body fat), and habitual exercise levels. The entire study should last approximately 24-months. Participants will be involved for 52-weeks. The investigators are looking to recruit 20 participants total for the feasibility trial. The investigators hypothesize that recruitment rates, drop-out rates, and adherence to the intervention will support a larger definitive trial.

NCT ID: NCT03407287 Terminated - Atrial Fibrillation Clinical Trials

Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status

PIVA
Start date: January 8, 2018
Phase:
Study type: Observational

The aim of this study is to determine the effects of fluid alternations, hemodynamic changes, mechanical ventilation, pharmacologic agents, positional changes, and comorbidities on the Peripheral Intravenous waveform Analysis (PIVA) signal.

NCT ID: NCT03382613 Terminated - Atrial Fibrillation Clinical Trials

A Study to Quantify Use of Anticoagulation to Improve Management of Atrial Fibrillation

QUANTUM AF
Start date: December 29, 2017
Phase:
Study type: Observational

The purpose of this study is to evaluate the impact of a hospital quality improvement (QI) program on the use of guideline-recommended oral anticoagulants (OAC) in hospitalized patients with atrial fibrillation (AF) at risk for ischemic stroke. Specifically, the study will determine whether the intervention, compared to Usual Care, will result in a greater increase in the proportion of patients with AF at risk for ischemic stroke who are appropriately treated with OAC.

NCT ID: NCT03377751 Terminated - Atrial Fibrillation Clinical Trials

Does VoltagE Guided Additional Ablation Improve Procedural Outcome of Atrial Fibrillation Ablation?

Start date: February 15, 2018
Phase: N/A
Study type: Interventional

This study is designed to investigate whether pulmonary vein isolation(PVI) plus stepwise additional ablation approach based on the degree of low voltage area versus PVI only can improve procedure outcome in persistent atrial fibrillation(AF) patients.

NCT ID: NCT03370536 Terminated - Atrial Fibrillation Clinical Trials

ECGi Ibutilide: Effect of Ibutilide on AF Source Location and Organization

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

This is a prospective, multi-center, non-randomized, un-blinded, observational trial.

NCT ID: NCT03349476 Terminated - Clinical trials for Paroxysmal Atrial Fibrillation

Model Based Fast Anatomical Mapping

MFAM
Start date: April 16, 2018
Phase: N/A
Study type: Interventional

This prospective, multicenter observational study will examine the ability of model based fast anatomical mapping (mFAM) to create left atrial (LA) geometry for atrial fibrillation ablation.

NCT ID: NCT03274401 Terminated - Atrial Fibrillation Clinical Trials

Screening for Atrial Fibrillation in Pulmonary Embolism Study -SAFE-PE Study

SAFE-PE
Start date: September 13, 2017
Phase: N/A
Study type: Interventional

Patients with newly diagnosed pulmonary embolism and high thromboembolic risk will be randomized to screening for atrial fibrillation or standard of care using intermittent ECG registration for at least two weeks.