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Asthma clinical trials

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NCT ID: NCT06422689 Recruiting - Asthma Clinical Trials

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care

ANCHOR
Start date: May 10, 2024
Phase: Phase 4
Study type: Interventional

ANCHOR is a prospective, multi-center, phase IV, interventional, single-arm, open-label study of 2,000 adult participants with symptomatic asthma requiring the use of rescue therapy aimed to compare the asthma exacerbation rates before and after switching from albuterol or levalbuterol to albuterol plus budesonide inhalation aerosol as rescue therapy.

NCT ID: NCT06422663 Recruiting - Clinical trials for Moderate-to-Severe Asthma

A Study To Evaluate The Treatment Pattern Of Moderate-to-Severe Asthma Patients In China

PRESENT
Start date: March 22, 2024
Phase:
Study type: Observational

This is a Prospective, Observational, Multicentre Study to describe treatment pattern changes of uncontrolled moderate-to-severe asthma patients in China. Sponsor by Astrazeneca Investment(China) Co., LTD.

NCT ID: NCT06419413 Recruiting - Asthma Clinical Trials

A Translational Study to Describe Clinical Characteristics, Biomarkers and to Identify Phenotypes and Endotypes Associated With Differential Outcomes in Chinese Population

Start date: January 18, 2024
Phase:
Study type: Observational

A Translational Study to Describe Asthma Patient Clinical Characteristics, Treatment Patterns, Biomarkers and to Identify Phenotypes and Endotypes associated with Differential Outcomes that may Support Future Development of Personalised Treatment Strategies in Chinese Population

NCT ID: NCT06407154 Recruiting - Stroke Clinical Trials

Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study, 2nd Wave

CLIMATE-II
Start date: May 21, 2024
Phase:
Study type: Observational

The CLIMATE-II Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and benefit perception, self-efficacy, health literacy, degree of urbanisation of the patients' administration district and characteristics of the patients' neighborhood are associated with these effects.

NCT ID: NCT06407011 Recruiting - Asthma; Status Clinical Trials

Effects of Swedish Massage Prior Circuit Breathing Training on Asthma

Start date: January 15, 2024
Phase: N/A
Study type: Interventional

The objective of this study was to determine the effects of Swedish massage prior circuit breathing training on asthma control and respiratory function in patients with asthma.

NCT ID: NCT06388460 Recruiting - Childhood Asthma Clinical Trials

Asthma Link Effectiveness Trial: Cluster Randomized Controlled Trial

Start date: April 4, 2024
Phase: N/A
Study type: Interventional

The goal of this cluster RCT is to determine the effectiveness of Asthma Link, a school supervised asthma therapy program, compared with an educational asthma workbook, in improving asthma symptoms for children with poorly controlled asthma aged 5-14.

NCT ID: NCT06385236 Recruiting - Clinical trials for Moderate to Severe Asthma

Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping

EPIPHANY
Start date: February 19, 2024
Phase: Phase 4
Study type: Interventional

In this study, a new method will be used to evaluate response to 2 approved biologic therapies, and assess how well each patient responds to each asthma treatment. This study will measure the response to these treatments using genomic and biologic measurements obtained from participants biosamples. By evaluating response to 2 different biologic therapies, this study has the potential to provide an in-depth understanding of the mechanisms underlying severe asthma that will inform and change treatment decisions, and may ultimately lead to a change in the way that asthma patients are evaluated for potential personalized therapies and maximize the probability that the subject will respond to treatment.

NCT ID: NCT06376045 Recruiting - Asthma Clinical Trials

A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma

Start date: May 24, 2024
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to describe the efficacy of rocatinlimab in reducing asthma exacerbations.

NCT ID: NCT06372496 Recruiting - Asthma Clinical Trials

Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma

Start date: April 16, 2024
Phase: Phase 4
Study type: Interventional

The goal of this study is to assess and compare the effectiveness of fluticasone furoate/umeclidinium bromide/vilanterol trifenatate (FF/UMEC/VI) with inhaled corticosteroids/long-acting beta-2 agonists (ICS/LABA) in adult participants with uncontrolled asthma

NCT ID: NCT06372249 Recruiting - Asthma in Children Clinical Trials

A Clinical Trial of Soluble Fiber for Asthma

Start date: April 2, 2024
Phase: Phase 2
Study type: Interventional

Randomized controlled trial of soluble fiber (NOVELOSETM 3490). Participants will complete an ASA 24 dietary recall questionnaire to access their fiber intake. If eligible for the study, participants will be supplemented to their target fiber dosage with either soluble fiber (NOVELOSETM 3490) or placebo. Collection of blood serum, fecal samples, and nasal wash will aid in analyzing the microbes present in one's gut and how fiber and diet may impact it. Thus, allowing researchers to better understand the pathways that may connect diet and asthma and if it is possible to improve asthma by altering one's diet.