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Arthritis of Hip clinical trials

View clinical trials related to Arthritis of Hip.

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NCT ID: NCT05957822 Not yet recruiting - Prostate Cancer Clinical Trials

Goal-directed vs Preemptive Tranexamic Acid Administration in Non-cardiac Surgery

Start date: November 1, 2023
Phase: Phase 4
Study type: Interventional

The present study is a multi-center randomized prospective non-inferiority trial. The study's primary objective is to compare the coagulation profile upon using two different TXA administration strategies: empirical TXA administration vs. viscoelastic test-based goal-directed TXA administration in high-risk non-cardiac surgery. The secondary objectives include comparing the amount of bleeding, incidents of hyper-fibrinolysis, thromboembolic complications, and postoperative seizures. Researchers assumed that goal-directed tranexamic acid (TXA) administration using viscoelastic field tests would not be inferior to the empirical TXA administration strategy in reducing postoperative bleeding and hyper-fibrinolysis. It also would be beneficial in lowering TXA-induced thromboembolic complications and seizures.

NCT ID: NCT05956769 Not yet recruiting - Arthritis of Hip Clinical Trials

Goal-directed vs Preemptive Tranexamic Acid Administration in Total Hip Arthroplasty

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

The present study is a multi-center randomized prospective placebo-controlled non-inferiority trial. The study's primary objective is to compare the amounts of postoperative bleeding using two different TXA administration strategies: empirical TXA administration vs. viscoelastic test-based Goal-directed vs Preemptive Tranexamic Acid Administration in total hip arthroplasty. The secondary objectives include comparing the incidents of hyper-fibrinolysis, thromboembolic complications, and postoperative seizures. Researchers assumed that goal-directed tranexamic acid (TXA) administration using viscoelastic field tests would not be inferior to the empirical TXA administration strategy in reducing postoperative bleeding and hyper-fibrinolysis. It also would be beneficial in lowering TXA-induced thromboembolic complications and seizures.

NCT ID: NCT05736016 Not yet recruiting - Clinical trials for Surgical Procedure, Unspecified

Medial Wedge Insoles to Improve Gait in Persons After Total Hip Replacement

Start date: February 2024
Phase: N/A
Study type: Interventional

The study will test the hypothesis, that the use of medial wedge insoles in people participating in comprehensive rehabilitation between 1-6 months after total hip replacement, and not having a varus deformity of the knee or symptomatic arthrosis of the medial knee compartment, will improve patient's functioning, the symmetry of gait and stance compared to persons using sham insoles. The participants will undergo a 6-week program of in-patient rehabilitation aimed at: pharmacologic and non-pharmacologic pain management, improvement of vascular function, cardiopulmonary function, functions of skeletal muscles, range of motion and stability of peripheral joints, gait function, body position. The rehabilitation program will also address individual needs with psychotherapy and vocational therapy. The study will help to identify correlations between gait parameter change and functional improvement during the rehabilitation following THR. Study participants will be provided with individually made corrective medial wedge insoles or sham insoles and instructed to use them during gait training and everyday activities. Functional parameters will be examined at the study entry, at the end of 6 weeks of intervention, and 6 weeks following discharge.

NCT ID: NCT05366712 Recruiting - Hip Osteoarthritis Clinical Trials

Nexus Evaluation Primary Trident II Uncemented Shell

NEPTUNE
Start date: June 1, 2022
Phase: N/A
Study type: Interventional

This is a prospective cohort study assessing the survival of a new acetabula component which is based on the original Trident acetabular system (cementless shell) which is used for Total Hip Arthroplasty. The manufacturer recently introduced the evolution of this product, the Trident® II acetabular shell which was launched in 2017. This implant is CE marked and is now widely available for the UK market, however has minimal clinical outcomes data to support its use. As part of a stepwise introduction of devices to orthopaedic practice. This study will report the 10 year implant survival and patient functional outcomes of this new implant.

NCT ID: NCT05065775 Completed - Anesthesia Clinical Trials

Bioavailability of Intranasal Dexmedetomidine

INDEX
Start date: November 1, 2021
Phase: Phase 4
Study type: Interventional

Aim of this study is to characterize the pharmacokinetics of dexmedetomidine in supine, anesthetized adult patients after intranasal dosing.

NCT ID: NCT04928924 Enrolling by invitation - Arthritis of Hip Clinical Trials

Immediate Post-THA Functional Assessment

Start date: April 26, 2021
Phase:
Study type: Observational

The objective of this study is to investigate the feasibility of functional 3D biomechanical assessment and EMG analysis of gait and a sit to stand tasks in the immediate post-operative phase following total hip arthroplasty.

NCT ID: NCT04441112 Completed - Arthritis Knee Clinical Trials

Intraarticular Injections of the Hip and Knee With Triamcinolone Versus Ketorolac: A Randomized Controlled Trial

Start date: May 20, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

Clinicians commonly utilize intraarticular injections to treat symptomatic primary arthritis. Steroid injections are common yet have immune-modulating effects and can alter gene expression which may delay definitive arthroplasty and further damage cartilage. Non-steroidal anti-inflammatory (NSAID) injections may offer a safer profile due to their differing mechanism of action; however, there is a relative dearth of information regarding their efficacy. This non-inferiority study compares the effectiveness of triamcinolone versus ketorolac in treating symptoms of moderate to advanced primary osteoarthritis of the hip and knee.

NCT ID: NCT03602105 Active, not recruiting - Arthritis of Hip Clinical Trials

Better Before - Better After: Prehabilitation Program for Older Patients Awaiting Total Hip Replacement

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Health professions need to prepare for the large increase in the number of older people with OA requiring health services including TJA surgery. Older age and poor physical function influences the postoperative prognosis of TJA. At discharge from hospital after TJA, studies have shown that gait speed can be severely impaired among older patients. The investigators hypothesize that an exercise program of 6-12 weeks will be beneficial for patients that are undergoing TJA.

NCT ID: NCT03540667 Completed - Clinical trials for Osteoarthritis, Knee

Study of Hip and Knee Arthroplasty in South Africa

Start date: May 7, 2018
Phase:
Study type: Observational

This multi-site, observational, prospective study aims to investigate current practice and associated outcomes for patients scheduled for elective unilateral total hip or knee arthroplasty in South Africa.This information will provide baseline values, against which effects of implementing a multidisciplinary enhanced care protocol for arthroplasty patients will be compared (the subsequent study).

NCT ID: NCT03375112 Completed - Arthritis of Hip Clinical Trials

Fascia Iliaca Blocks for Pain Control After Total Hip Arthroplasty

Start date: July 31, 2017
Phase: Phase 4
Study type: Interventional

The fascia iliaca compartment block (FICB) is a regional block that anesthetizes the femoral, obturator, and lateral femoral cutaneous nerves around the hip. The purpose of this study is to determine whether FICB can reduce postoperative pain and increase progress with physical therapy after total hip arthroplasty (THA). This randomized, double-blind, clinical trial will randomize patients to receive either a FICB or placebo after THA. The primary outcomes will be pain scores reported by the patient post-operatively.