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Arrhythmias, Cardiac clinical trials

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NCT ID: NCT04937621 Completed - Clinical trials for SARS-CoV-2 Infection

Study of Arrhythmia and ECG Abnormalities in Patients With COVID-19

RYTHMO-COV
Start date: June 2, 2020
Phase:
Study type: Observational

Cardiac involvement has been described in Severe Acute Respiratory Syndrome - Coronavirus-2 (SARS-CoV-2) infection. Although there are no approved drugs to prevent or treat SARS-CoV-2 infection at present time, several medications used have the potential to increase QT interval and eventually provoke torsades de pointe. The investigators therefore create a study that include all patients with SARS-CoV-2 infection having an electrocardiogram (ECG). The investigators evaluate the percentage of patients with ECG abnormalities, describe the abnormalities and evaluate the occurrence of syncope, ventricular arrhythmia and corrected QT (cQT) interval modification in patients receiving treatment.

NCT ID: NCT04922281 Recruiting - Clinical trials for Cardiovascular Diseases

Insertable Cardiac Monitor-Guided Early Intervention to Reduce Atrial Fibrillation Burden Following Catheter Ablation

ICMREDUCE-AF
Start date: February 28, 2022
Phase: Phase 4
Study type: Interventional

To prospectively investigate the efficacy of an insertable cardiac monitor-guided atrial fibrillation (AF) management in reducing subsequent AF burden in patients with persistent or paroxysmal AF undergoing atrial catheter ablation (CA).

NCT ID: NCT04921501 Recruiting - Clinical trials for Ventricular Arrhythmias

Evaluation of Electrocardiographic Measurements by High Density Electrode ECG (ECG-HD)

ECG-HD
Start date: April 6, 2021
Phase: N/A
Study type: Interventional

Cardiac electrical activity is detected on the body surface with conventional electrocardiography involving 12 leads (ECG 12). A limitation of the current ECG technique is that recordings are obtained from only 6 independent precordial leads pairs ; which may miss cardiac potentials from spatially limited regions. More extensive sampling of the body surface may contribute to additional clinical information. The present study investigates the additional sensitivity of ECG using 128 body surface leads (High Density (HD) ECG) in measuring global or regional cardiac activity.

NCT ID: NCT04919902 Recruiting - Atrial Fibrillation Clinical Trials

Prague Registry of Electric Cardioversion

PRAGUE-ECV
Start date: January 1, 2020
Phase:
Study type: Observational [Patient Registry]

This single-center observational registry follows contemporary efficacy and short-term complications of elective electric cardioversion.

NCT ID: NCT04918303 Completed - Clinical trials for Ventricular Tachycardia

Skin Sympathetic Nerve Activity and Cardiac Arrhythmia

SKNA
Start date: May 3, 2021
Phase: N/A
Study type: Interventional

Sympathetic tone is important in cardiac arrhythmogenesis. The simultaneous recording of sympathetic nerve activity (SNA) and electrocardiogram (ECG) was obtained by invasive method. The purpose of this protocol is to further develop this recording method to turn it into a new non-invasive tool for arrhythmia prediction and detection. This method may also be useful in validating the results of surgical procedures aimed at sympathetic denervation

NCT ID: NCT04904809 Completed - Arrhythmia Clinical Trials

Perclose Multi-Access Duplex Ultrasound (DUS) Study

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The aim of this prospective, single-arm, United States (US) multi-center, descriptive clinical study is to evaluate the safety of multiple access site closure in a single vein with the SMC System by scheduled DUS at discharge and at 30 days (if vascular complications observed at discharge) in asymptomatic or non-visible subjects.

NCT ID: NCT04899596 Completed - Neonatal Arrhythmia Clinical Trials

High Risk Factor, Clinical Feature, and Follow up of Neonatal Arrhythmia

Start date: October 1, 2019
Phase:
Study type: Observational

This study included 189 newborns (77 male,112 female) diagnosed with arrhythmia in the NICU of Children's Hospital of Chongqing Medical University, China, from January 2015 through December 2019. To investigate the high-risk factors, clinical manifestations, and clinical outcomes of neonatal arrhythmia.

NCT ID: NCT04884607 Completed - Clinical trials for Cardiovascular Diseases

Autonomic Nerve Stimulation Using External Auditory Canal Electrodes

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

- Purpose of the study This study aimed to investigate electrocardiogram measurement and subthreshold low-level autonomic nerve stimulation using external auditory canal electrodes among healthy adult participants - Study design Prospective, single-center, interventional, single-arm design - Study participants A total of 12 healthy adult participants without cardiovascular diseases will be recruited. - Study methods 1. Participant enrollment Study participants will be recruited by advertisement posters announced at the lobby of the hospital 2. Evaluation of electrocardiogram measurement from external auditory canal electrodes Participants are required to attach specially designed external auditory canal electrodes to their both ears to record electrocardiogram. Both electrocardiogram from the precordium and the ear would be simultaneously recorded and compared. 3. Evaluation of low-level autonomic nerve stimulation using external auditory canal Using the electrodes described above, Arnold's nerve will be stimulated with low-level electric impulses using TENS device. During and after the stimulation, heart rate variability will be measured to investigate the impact of nerve stimulation on autonomic function modulation on the heart.

NCT ID: NCT04884100 Completed - Atrial Fibrillation Clinical Trials

enHEART - Exploring Full Content of Optical Signals to Enhance Cardiac Arrhythmia Screening

enHEART
Start date: September 15, 2021
Phase: N/A
Study type: Interventional

This research will investigate the PPG signal morphology related to physiological and non- physiological changes in arrhythmia-related heart rate as well as the performance of the PPG-based features previously developed within the framework of the Mini-Holter study to discriminate between several cardiac arrhythmias. To this end, clinical data will be recorded on patients by using a wrist-based PPG monitor simultaneously with 12-lead ECG and intracardiac electrogram (EGM) signals at the university hospital in Lausanne. Importantly, this study will remain purely observational as it will not change the diagnostic and therapeutic management of the included patients, nor will it interfere with the time course of the procedures. The aim of enHEART study is to validate on a larger database the ability of several previously developed PPG-based features to detect a variety of cardiac arrhythmias.

NCT ID: NCT04876963 Active, not recruiting - Clinical trials for Cardiovascular Diseases

HOLT-ED: Holter-monitoring in End-stage Renal Disease

Start date: September 1, 2021
Phase:
Study type: Observational [Patient Registry]

The main objective of this prospective cohort study is to assess arrhythmia burden and glycemic variability in a multicenter cohort of patients with end-stage renal disease using a sufficient observation period in order to identify arrhythmia burden and type and characterize associations with patient characteristics and dialysis treatment, glycemic variability and subsequent risk of adverse outcomes.