Combined Effects of Energy Density and Eating Rate on Appetite

Appetite Clinical Trial

Official title:

Combined Effects of Energy Density and Eating Rate on Energy Intake and Biomarkers of Satiety

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01406886
• Other study ID #: H09-28
• Status: Completed
• Phase: N/A
• First received: July 5, 2011
• Last updated: October 15, 2017
• Start date: December 2009
• Est. completion date: June 2010

Study information

• Verified date: October 2017
• Source: United States Army Research Institute of Environmental Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study will examine the independent and combined effects of energy density and eating rate on appetite and endocrine mediators of appetite. Increasing eating rate and energy intake are expected to additively increase energy intake.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: June 2010
• Est. primary completion date: June 2010
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 55 Years

Eligibility

Inclusion Criteria:

• BMI 18-27 kg/m2

• Weight stable

Exclusion criteria:

• Chronic used of OTC or prescription drugs known to affect metabolism

• Chronic disease

• Gastric bypass surgery

• Disordered eating

• Pregnant or breastfeeding

Related Conditions & MeSH terms

• Appetite

Intervention

Behavioral:
• Eating rate

Locations

Country	Name	City	State
United States	USARIEM	Natick	Massachusetts

Sponsors (1)

Lead Sponsor	Collaborator
United States Army Research Institute of Environmental Medicine

Country where clinical trial is conducted

United States, 

References & Publications (1)

Karl JP, Young AJ, Rood JC, Montain SJ. Independent and combined effects of eating rate and energy density on energy intake, appetite, and gut hormones. Obesity (Silver Spring). 2013 Mar;21(3):E244-52. doi: 10.1002/oby.20075. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Energy intake		1 meal
Secondary	Subjective appetite		0-180 min
Secondary	Postprandial peptide-YY response		0-180 min
Secondary	Postprandial ghrelin response		0-180 min
Secondary	Postprandial glucagon-like peptide-1 response		0-180 min
Secondary	Postprandial pancreatic polypeptide response		0-180 min