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Appendicitis clinical trials

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NCT ID: NCT05571566 Completed - Appendicitis Clinical Trials

The Impact of a Patient Education Tool for Appendicitis

Start date: December 3, 2019
Phase: N/A
Study type: Interventional

Hypothesis/Study question (brief introduction of the question studied; about 5 lines) Appendicitis is the most common acute surgical admission to the pediatric surgery service at the MCH. The need for surgery can provoke anxieties for patients. Patient education materials are meant to improve knowledge, set expectations, and improve the overall hospital experience for patients and their families, and are already being widely implemented for elective surgeries in the context of ERAS pathways. This study aims to develop an effective patient and family education tool, with the goal of improving patient education and satisfaction with care in the emergency surgery setting. Study objectives 1. Utilize evidence-based methods to evaluate the success of implementation of a patient and family-centered education tool for appendicitis. 2. Develop and validate a pre- and post- education patient satisfaction and experience survey in the realm of pediatric surgery. 3. Inform the development of the education tool and survey through multidisciplinary and patient/family input. 4. Implement a patient/family-centered education tool in an emergency surgical setting.

NCT ID: NCT05511194 Not yet recruiting - Appendicitis Clinical Trials

Safety and Efficacy of ERAS Therapeutic Protocol for Complicated Appendicitis in Children

ERAS
Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Complicated appendicitis in pediatrics is frequent, potentially serious and complex to manage. The implementation of a ERAS model would allow optimizing perioperative care, offering a shorter hospital stay, reducing complications associated with medical care and costs, although adequate multidisciplinary management is necessary. The objective of the study is to evaluate the safety and efficacy of the application of a ERAS therapeutic protocol and compare them with the safety and efficacy of conventional management in children with complicated appendicitis.

NCT ID: NCT05488080 Not yet recruiting - Pain Clinical Trials

PAINED: Project Addressing INequities in the Emergency Department

PAINED
Start date: August 1, 2024
Phase: N/A
Study type: Interventional

Racial and ethnic inequities in health care quality have been described across a broad range of clinical settings, patient populations, and outcomes. Our overarching goal is to eradicate health care inequities through evidence-based interventions. The objectives of this proposal are to develop and test the impact of two interventions on overcoming clinician implicit bias and mitigating inequities in the management of pain among children seeking care in the emergency department for the treatment of appendicitis or long bone fractures.

NCT ID: NCT05473325 Not yet recruiting - Obesity Clinical Trials

Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)

BRANCH-P
Start date: January 1, 2023
Phase:
Study type: Observational

This research programme seeks to combine the resources of NHS primary care, with the leading spectroscopic work in low-magnetic fields of the Wilson Group (Nottingham Trent University) to demonstrate the potential for benchtop Nuclear Magnetic Resonance (NMR) spectroscopy in human clinical pathology. This is an instrument assessment study for point of care viability which will also result in enhanced patient care (pending their consent) in blood screenings and metabolic health data.

NCT ID: NCT05470517 Completed - Acute Appendicitis Clinical Trials

Antibiotic Instillation in Appendicitis

Start date: January 5, 2023
Phase: Phase 2
Study type: Interventional

Appendicitis (inflammation of the wall of the appendix, causing pain and tenderness in the abdomen) has a range of severity that goes from simple to complicated. Complicated appendicitis may present with infected fluid inside of the abdomen or a perforation or hole in the intestines. This research is being done to determine if placing an antibiotic solution in the abdomen at the time the appendix is removed is a safe procedure in patients between the ages of 3 and 18 years old with findings of complicated appendicitis. Johns Hopkins All Children's Hospital (JHACH)'s current standard of care for patients with complicated appendicitis includes suctioning the infected fluid out of the abdomen at the time the appendix is removed. As part of this study, the investigators would like to see if patients with complicated appendicitis will benefit from routine care plus leaving an antibiotic solution inside the abdomen, after fully suctioning the infected fluid out of the abdomen.

NCT ID: NCT05434988 Completed - Obesity Clinical Trials

Outcome and Quality of Life in Obese Patients Underwent Laparoscopic vs. Open Appendectomy

Start date: March 1, 2020
Phase:
Study type: Observational

Although obesity is a popular reason for choosing laparoscopic appendectomy (LA) versus open appendectomy (OA), however, the question of whether there is a difference remains. The goal of the present study is to investigate if there is a difference between OA and LA in obese patients. In the present study, Fifty-eight obese patients were diagnosed with acute appendicitis according to Alvarado score at the department of surgery at Suez Canal university hospitals from March 2020 till August 2021were included. The study participants were assigned to two groups, after their approval: LA and OA. The investigators hypothesized that evaluating the Outcome and Quality of life of laparoscopic appendectomy for the obese patients would be a potential step for standardization of the laparoscopic approach for obese patients who are arranged for appendectomy.

NCT ID: NCT05430633 Completed - Appendicitis Clinical Trials

Laparoscopic Versus Open Appendectomy in Pregnancy

Start date: November 1, 2021
Phase:
Study type: Observational

The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.

NCT ID: NCT05427266 Not yet recruiting - Pain Clinical Trials

Laparoscopic Transversus Abdominis Plane Block (LTAP) for Appendicectomy Versus Standard Port Site Treatment

TapBlock
Start date: July 2022
Phase: N/A
Study type: Interventional

This study aims to compare Laparoscopic assisted LTAP (Transversus Abdominis Plane) to standard port-site infiltration in terms of post-operative visual analogue scores (VAS) for pain at 3, 6, 12 and 24 hours following laparoscopic appendicectomy Tap Block is a standard conventional analgesia protocol for laparoscopic appendicitis used in Beaumont Hospital, and other hospitals throughout Ireland. The medicinal product for both groups is the same - Bupivacaine. The mode of administration is what this study is reviewing: Control group (Standard port site infiltration) and Study Group - Laparoscopic Transversus Abdominis Plane Block

NCT ID: NCT05401188 Completed - Appendicitis Clinical Trials

Clinical Trial for a Outpatient Clinical Management of Urgent Laparoscopic Appendectomy

ASI
Start date: June 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the safety and efficacy of outpatient management of uncomplicated acute appendicitis. For this purpose, a randomized clinical trial was designed. Selected patients who have undergone surgery for acute appendicitis are randomized into two groups. One group with hospitalization and another group without admission.

NCT ID: NCT05391269 Completed - Appendicitis Clinical Trials

Review of the Pathological Results of Appendectomy Specimens

Start date: January 1, 2021
Phase:
Study type: Observational

This is a retrospective review study to evaluate the histopathological findings post appendectomy