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Aortic Aneurysm clinical trials

View clinical trials related to Aortic Aneurysm.

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NCT ID: NCT05266781 Completed - Clinical trials for Thoracoabdominal Aortic Aneurysms

A PROpensity Score Matching Analysis on ENDovascular vs Open Thoraco-Abdominal Aortic Aneurysm Repair (PRO-ENDO TAAA Study)

PRO-ENDO TAAA
Start date: April 1, 2022
Phase:
Study type: Observational

The purpose of the registry is to compare the surgical and endovascular approaches to the treatment of thoracoabdominal aortic aneurysms.

NCT ID: NCT05247944 Completed - Vascular Diseases Clinical Trials

F-BEVAR vs Open Surgery for Complex Abdominal Aortic Aneurysm

Start date: January 2010
Phase:
Study type: Observational

The aim of the present study was to investigate outcomes of a propensity matched series of patients treated with F-BEVAR and open surgery repair for complex abdominal aortic aneurysm in two aortic high-volume centres.

NCT ID: NCT05234892 Recruiting - Clinical trials for Abdominal Aortic Aneurysm

ALTo endogrAft Italian Registry

ALTAIR
Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

The aim of present study is to evaluate intraoperative, peri-operative, and post-operative results in patients treated by the ALTO stent graft (Endologix Inc. Irvine, Calif) for elective Abdominal Aortic Aneurysm repair in a multicentric consecutive experience.

NCT ID: NCT05230264 Not yet recruiting - Surgery Clinical Trials

Sex-specific Differences in the Stress Response to Abdominal Aortic Aneurysm Repair

SSStressAAA
Start date: February 1, 2022
Phase:
Study type: Observational

It is recognised that women are at greater risk of death, complications and longer hospital stay following intact abdominal aortic aneurysm (AAA) repair, and the reason for this is not yet established. This disparity in outcomes for women compared to men is also recognised in other forms of cardiovascular surgery, which raises the question of whether women and men are reacting differently to the stress of operative repair. This study aims to examine whether there are differences baseline stress markers and in the stress response to AAA repair between men and women. It will also examine whether markers of stress are associated with poor clinical outcomes and slower recovery (indicated by longer hospital stay). The study will take the form of an observational cohort study. It will not alter any of the treatment that men and women receive, but will monitor their stress levels using physiological markers (through ECG (electrocardiogram) monitoring using a non-invasive holter, biochemical markers using blood samples (which will be taken at the same time as routine testing, so as not to require further invasive procedures), and psychological testing, using short forms that the patient will be able to fill out independently at different stages of their recovery. Clinical data will be used to look for relevant factors (clinical history or medications) which may alter the stress markers we are observing, and to compare outcomes with markers of stress. Patients will be asked for their consent to share their data with the research team in order to participate in the study. It will be made clear that there will be no change in their clinical or operative management if they participate in the study and they will be able to withdraw consent for further participation at any time.

NCT ID: NCT05224219 Recruiting - Clinical trials for Thoracoabdominal Aortic Aneurysm

Modified Preloaded System for Renal Arteries in Fenestrated Endografting (MPSRA)

MPSRA
Start date: January 1, 2019
Phase:
Study type: Observational

Advanced Endovascular repair of aneurysms and dissections involving thoraco-abdominal (type I-IV) and complex abdominal (juxta and para-renal) aorta is a ground-gaining procedure allowing favorable results in high surgical risk patients. The availability of iliac vessels navigation and the major role of lower leg perfusion in order to decrease the risk of spinal cord ischemia during these complex procedures, led to the development of devices with lower sheaths sizes and to the improvement of the technique with preloaded devices for visceral vessels in order to navigate in hostile anatomies or when an iliac access is not available. The aim of the study is to evaluate in a prospective single center observational setting, the outcomes, safety and efficacy of the modified preloaded system for renal arteries in fenestrated endografting in the routine treatment of paravisceral and thoraco-abdominal aortic pathologies.

NCT ID: NCT05197543 Active, not recruiting - COVID-19 Clinical Trials

AAA Rupture Risk Assessment in COVID-19 Pandemic

Start date: March 12, 2020
Phase:
Study type: Observational

The acute phase of the COVID-19 pandemic requires a redefinition of healthcare system to increase the number of available intensive care units for COVID-19 patients. This leads to the postponing of elective surgeries including the treatment of abdominal aortic aneurysm (AAA). The probabilistic rupture risk index (PRRI) recently showed its advantage over the diameter criterion in AAA rupture risk assessment. Its major improvement is in increased specificity and yet has the same sensitivity as the maximal diameter criterion. The objective of this study was to test the clinical applicability of the PRRI diagnostic method in a quasi-prospective observational patient cohort study.

NCT ID: NCT05195905 Recruiting - Clinical trials for Thoracoabdominal Aortic Aneurysm

PMEG for Repair of Pararenal and Thoracoabdominal Aortic Aneurysm

Start date: June 6, 2023
Phase: N/A
Study type: Interventional

The primary objective is to evaluate the safety and effectiveness of surgeon modified endografts for the treatment of pararenal and thoracoabdominal aortic pathology in patients who are not candidate for traditional open repair due to comorbid issues and their anatomy is not amenable to commercially available endografts.

NCT ID: NCT05183373 Recruiting - Coronary Disease Clinical Trials

Inflammation and Clotting Abnormalities in Aneurysmal Coronary Artery Disease

CARE-ANUERYSM
Start date: January 10, 2022
Phase:
Study type: Observational

The main objective of the CARE-ANEURYSM project is to evaluate inflammation and clotting abnormalities in patients with aneurysmal coronary artery disease in relation to patients with abdominal aortic aneurysm or coronary artery disease (acting as controls).

NCT ID: NCT05179967 Recruiting - Clinical trials for Juxtarenal Abdominal Aortic Aneurysm

Safety and Efficacy Study of WeFlow-JAAA Stent Graft System for Complex Abdominal Aortic Aneurysm(GREAT Study)

Start date: February 23, 2022
Phase: N/A
Study type: Interventional

A prospective, multi-center, objective performance criteria clinical trial to evaluate the safety and efficacy of WeFlow-JAAA stent graft system manufactured by Hangzhou Endonom Medtech Co., Ltd. for the complex abdominal aortic aneurysm.

NCT ID: NCT05172830 Recruiting - Clinical trials for Abdominal Aortic Aneurysm

Hellenic Registry of Ovation Alto™ Abdominal Stent Graft System

Start date: January 1, 2021
Phase:
Study type: Observational [Patient Registry]

This is a Hellenic Registry including both retrospective and prospective subjects receiving the Ovation Alto™ Abdominal Stent Graft System ("Ovation Alto™ Abdominal Stent Graft System Post-Market Study") in the treatment of abdominal aortic aneurysms (AAA). The Ovation Alto™ Hellenic Registry is intended to expand the clinical knowledge base by collecting data on subjects treated with the Ovation Alto™ Abdominal Stent Graft System in actual clinical practice during the first post-operative year.