Anterior Cruciate Ligament Injury Clinical Trial
Official title:
Long-term Follow-up of Anterior Cruciate Ligament Injury
Anterior cruciate ligament (ACL) rupture is one of the most common sports-related knee
injuries. Because it is such a significant injury - requiring a long period of rehabilitation
before the injured person is ready to return to physical activity, the burden of injury is
high. This can help to explain why so much of orthopaedic research is devoted to evaluating
the outcomes of ACL injury. However, while there has been extensive study of short-term (up
to 5 years after injury) outcomes, few studies have followed patients beyond 15 years after
their ACL injury. This is important because long-term follow-up can provide key insights to
guide the information provided to newly injured patients (e.g. to help set realistic
expectations of what the injured person can expect of their knee function in the future), and
help us evaluate the efficacy of previous treatments.
The primary aim is to assess the influence of an acute ACL injury on knee function and
quality of life, 32-37 years after the index injury. Approximately 300 patients injured
between 1980 and 1985 will be invited to participate in the study. Patient- and
clinician-reported outcomes, and radiographic osteoarthritis will be evaluated.
Patients injuring their ACL between 1980 and 1985 have periodically been followed since the
injury. Now, we plan to contact all patients and invite them to participate. The patients
will be asked to
1. complete a questionnaire battery
2. visit the movement laboratory at Linköping University for an objective assessment of
knee function and
3. have an x-ray of both knee joints.
Baseline information including associated injuries, treatment and activity level exist for
all the patients. At that time, rehabilitation was normally completed after 4-6 months for
non-operatively treated patients, and nine months after ACL surgery.
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