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Angina, Stable clinical trials

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NCT ID: NCT02294942 Completed - Clinical trials for Stable Angina Pectoris

Extended-Release RANCAD in the Patients With Stable Angina Pectoris

Start date: October 2014
Phase: Phase 3
Study type: Interventional

A double-blind, randomized, placebo-controlled, parallel study to evaluate the effects of add-on RANCAD on exercise tolerance and angina frequency in patients with stable angina pectoris.

NCT ID: NCT02291484 Completed - Clinical trials for Coronary Artery Disease

Comprehensive Cardiac CT Versus Exercise Testing in Suspected Coronary Artery Disease (2)

CRESCENT2
Start date: August 2013
Phase: Phase 3
Study type: Interventional

Multi-center, randomized-controlled trial comparing a comprehensive cardiac CT protocol with standard stress testing in patients with stable chest pain complaints.

NCT ID: NCT02285322 Active, not recruiting - Stroke Clinical Trials

Predictors of Blood Pressure Control and Associations With Cardiovascular Diseases in Individuals With High Blood Pressure: a CALIBER Study

Start date: January 2014
Phase: N/A
Study type: Observational

Current guidelines for the clinical management of hypertension in adults recommend to achieve and maintain blood pressure levels of <140/90 mmHg. However, it is uncertain what proportion of individuals identified with high blood pressure in primary care actually reach blood pressure control, what factors are associated with attainment of control and to what extent blood pressure control attainment is associated with cardiovascular diseases in a contemporary population of individuals diagnosed with high blood pressure. The aim of this study is to investigate the extent to which patients achieve blood pressure control and associated risk factors, time to attainment of blood pressure control and whether this time is associated with an increased risk of CVD onset, all-cause and cardiovascular disease and end-stage renal disease.

NCT ID: NCT02280850 Not yet recruiting - Angina, Stable Clinical Trials

Efficacy and Safety Study of Guanxin Shutong Capsule to Treat Chronic Stable Angina

Start date: October 2014
Phase: Phase 4
Study type: Interventional

Compared with placebo, assess of the efficacy and safety of Guanxin Shutong capsule to treat chronic stable angina (syndrome of blood stasis resistance), and the result will be used for the basis of later Ⅳ clinical trial.

NCT ID: NCT02279342 Terminated - Clinical trials for Coronary Artery Disease

the Effect of Febuxostat on Coronary Plaque Volume in Patients With Chronic Stable Angina and Hyperuricemia

Start date: October 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate the effects of febuxostat on coronary plaque volume in patients with chronic stable angina and hyperuricemia.

NCT ID: NCT02254252 Completed - Stable Angina Clinical Trials

Effects of Nicorandil on Angina Symptoms in Patients With Coronary Slow Flow

Start date: March 2012
Phase: Phase 4
Study type: Interventional

Slow coronary flow is an angiographically diagnosed phenomenon defined as delayed opacification of epicardial arteries in the absence of significant arterial narrowing and blockade. Endothelial dysfunction at the level of microarteries have been proposed as the main pathological mechanism in this regard. Available evidence suggest that standard anti-angina medications (e.g. nitroglycerin) that solely target large coronary trunks might not provide adequate symptomatic relief in patients with slow coronary flow phenomenon. It is hypothesized that anti-angina medications which exert vasodilatory effects in large coronary arteries as well as small dividing branches might be superior to nitroglycerin in amelioration of angina symptoms. The present randomized clinical trial was thus designed and conducted to compare the short-term efficacy of nicorandil (a dual-acting anti-angina medication with effects on both large and small coronary vessels) with nitroglycerin in a group of patients with slow coronary flow presented with frequent angina episodes.

NCT ID: NCT02252406 Completed - Metabolic Syndrome Clinical Trials

Impact of Ranolazine in Blood Markers in Women With Angina and Metabolic Syndrome

IRMA
Start date: September 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the effects of ranolazine on different markers of cardiometabolic disease in women with stable angina.

NCT ID: NCT02244853 Active, not recruiting - Stroke Clinical Trials

Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease

Start date: September 2013
Phase: N/A
Study type: Observational

The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study. CALIBER links patient records from four different data sources: Clinical Practice Research Database (CPRD), MINAP (Myocardial Ischaemia National Audit Project registry) Hospital Episodes Statistics (HES), the Office for National Statistics (ONS).

NCT ID: NCT02232607 Completed - Angina Pectoris Clinical Trials

Efficacy and Safety of Lacidipine in Chronic Stable Angina

Start date: April 1998
Phase: Phase 2
Study type: Interventional

The aim of this study was to explore whether lacidipine at doses of 2 mg, 4 mg and 6 mg decreased the symptoms of angina, compared to placebo in patients with chronic stable angina

NCT ID: NCT02228603 Completed - Clinical trials for Cardiovascular Diseases

Exercise as a Life-long Medicine in Patients With Coronary Artery Disease

Start date: August 2014
Phase: N/A
Study type: Interventional

Exercise training is a core component in cardiac rehabilitation. Exercise adherence is, however, low after rehabilitation and the transition from supervised to unsupervised exercise is problematic for many patients with coronary artery disease. Therefore, it is important to provide extended services to improve exercise adherence and healthy lifestyle changes. The aim of this study is to assess the effect of a time-limited intervention following out-patient cardiac rehabilitation on exercise adherence and cardiovascular risk reduction.