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Aneurysm clinical trials

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NCT ID: NCT06446778 Enrolling by invitation - Safety Issues Clinical Trials

Haemodynamic Mechanisms and Multicentre Prospective Cohort Study of the Pipeline Flow-diverting Device for the Treatment of Intracranial Aneurysms. Evaluation of the Safety and Efficacy of the Pipeline Flow-diverting Device for the Treatment of Intracranial Aneurysms

Start date: September 1, 2022
Phase:
Study type: Observational [Patient Registry]

This study aims to collect clinical, laboratory, and imaging data from patients with unruptured intracranial aneurysms, and collect blood or urine samples for cotinine testing. The enrolled patients underwent Pipeline implantation. The purpose is to study the effect after Pipelineline implantation.

NCT ID: NCT06403423 Enrolling by invitation - Quality of Life Clinical Trials

Screening for Aortic Aneurysms in Inland Norway

NOR-AORTA
Start date: May 14, 2024
Phase:
Study type: Observational

The number of AAA-surgeries performed per capita is 3-4 times higher in Innlandet county, as compared to Oslo. The last three years the annual incidence of AAA requiring treatment has been 21.5 / 100 000 inhabitants in Innlandet, as compared to 6.6 / 100 000 in Oslo. The indication for surgery is the same in both regions. In Oslo, a screening program was established in 2011, reporting a prevalence of AAA of 2.6 %, but in Innlandet county all AAA are either symptomatic or incidental findings and the prevalence is unknown. The aetiology of the major difference in AAA prevalence between these two regions has not been previously explored.

NCT ID: NCT06380595 Enrolling by invitation - Clinical trials for Abdominal Aortic Aneurysm

Complex EVAR in Inflammatory and Infective Abdominal and Thoracoabdominal Aortic Aneurysms

CEVARII
Start date: February 21, 2024
Phase:
Study type: Observational

Complex endovascular aortic repair in inflammatory and infective perivisceral abdominal aortic aneurysms and thoracoabdominal aortic aneurysms (CEVARII) study is a collaborative international effort among vascular surgeons to establish a database on the global experience in the management of INAAs and IAAs. Ethical approval for the study was obtained from the Colorado Multiple Institutional Review Board (COMIRB) under protocol number 23-1533.

NCT ID: NCT06364293 Enrolling by invitation - Clinical trials for Intracranial Aneurysm

An Early Warning Model of Unfavorable Outcomes Following Endovascular Interventional Treatment of Intracranial Aneurysm

Start date: January 1, 2024
Phase:
Study type: Observational

Endovascular treatment has become one of the primary treatment methods for intracranial aneurysms. The unfavorable outcomes during follow-up included aneurysm recurrence and long-term incomplete-occlusion, which would bring a high risk of rebleeding and retreatment. Previous studies have tried to predict the outcomes of aneurysms following endovascular treatment based on aneurysm characteristics including morphology, embolization packing degree, etc, but the conclusion was inconsistent. Hemodynamics of aneurysms and parent artery played a greater role in predicting outcomes following endovascular treatments. Investigators also found that the outcomes were determined by many factors, in which the demography, clinical indicators, treatment methods, and material selection can not be ignored, and the mechanism of unfavorable imaging outcomes should be explored using large samples of clinical cases and numerous variable parameters. The pre-experiment of investigators confirmed that artificial intelligence technology can meet the calculation requirements for deep mining and analysis of large sample data. This study aims to use the deep learning model to identify relevant risk factors and weights, establish a stable and accurate prediction model, then incorporate the prospective study to verify the model. The results will be very helpful in accurately predicting the adverse outcomes such as recurrence and long-term non-occlusion after endovascular treatment and help to improve the therapeutic strategy and avoid risk factors. Besides, the occurrence of ischemic or hemorrhagic complications during follow-up may affect the final follow-up outcome, so the analysis was included as one of the outcome events to evaluate the prognosis after intervention.

NCT ID: NCT06215105 Enrolling by invitation - Aneurysm Cerebral Clinical Trials

Complex Aneurysm Registry - Real-World Evidence Data Collection Intracranial Aneurysm Treatment Devices

CAR
Start date: January 8, 2024
Phase:
Study type: Observational [Patient Registry]

To collect real-world evidence allowing assessment of functional, imaging, and safety outcomes of commercially available MicroVention devices used for the endovascular treatment of intracranial aneurysms (IA) at the direction of the treating physician.

NCT ID: NCT05800743 Enrolling by invitation - Aortic Dissection Clinical Trials

Evaluation of the GORE® Ascending Stent Graft

ARISEII
Start date: November 28, 2023
Phase: N/A
Study type: Interventional

The primary objective of ARISE II is to assess the safety and effectiveness of the GORE® Ascending Stent Graft device in the treatment of lesions involving the ascending aorta and aortic arch.

NCT ID: NCT05659641 Enrolling by invitation - Clinical trials for Cardiovascular Diseases

The Branch-based Intraoperative Stent System in the Treatment of Stanford A Aortic Dissection(BROAD)

BROAD
Start date: January 18, 2023
Phase: N/A
Study type: Interventional

The purpose of the study was to evaluate the safety and efficacy of a branched type intraoperative stent system for the treatment of Stanford type A aortic dissection

NCT ID: NCT05453240 Enrolling by invitation - Clinical trials for Intracranial Aneurysms

Post-Market Surveillance Study to Evaluate the Long-Term Safety and Effectiveness of the LVIS Device

LVIS PAS
Start date: November 17, 2020
Phase:
Study type: Observational

The proposed study is a multi-center single arm retrospective and prospective data collection, of patients treated with the LVIS device of specific sizes of 3.5mm, 4.0mm, 4.5mm, 5.5mm with up to 5 years follow-up. Information collected during the study will be standardized across centers to include pre-treatment baseline characteristics of patients including aneurysm(s) symptoms, procedural information, prespecified clinical safety events of interest, and follow-up imaging, clinical visits or telephone calls.

NCT ID: NCT05441618 Enrolling by invitation - Trauma, Brain Clinical Trials

Post Market Clinical Follow-Up Study on the Performance and Safety of Lyoplant®

LYOPLACE
Start date: April 2, 2024
Phase:
Study type: Observational

Retrospective, single center, single arm PMCF study on the performance and safety of Lyoplant® used for the replacement and extension of connective tissue structures in neurosurgery.

NCT ID: NCT05406869 Enrolling by invitation - Clinical trials for Coronary Calcified Disease

Clinical Trials of Pulsed Sonic Balloon Dilatation Catheter and Pulsed Sonic Generater

Start date: May 6, 2022
Phase: N/A
Study type: Interventional

The prospective, multicenter, single- arm study is designed to verify the safety and efficacy of pulsed sonic balloon dilatation catheter and pulsed sonic generater in the treatment of coronary calcification lesions.