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Anesthesia clinical trials

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NCT ID: NCT05427292 Completed - Anesthesia Clinical Trials

Combination of Serratus Anterior and Pectoral Nerve Blocks (PECS II) as Main Anesthetic Method in Breast Cancer Surgery

Start date: July 7, 2022
Phase:
Study type: Observational [Patient Registry]

Aim of this study is to determine the success of combined serratus anterior and PECS-2 block as the main anesthetic method in breast cancer surgery and also to investigate the patient acceptability of this combination and its relationship with surgeon satisfaction.

NCT ID: NCT05414721 Completed - Anesthesia Clinical Trials

The Effects of Low Flow and Normal Flow Desflurane Anesthesia

Start date: May 28, 2021
Phase: N/A
Study type: Interventional

Aging is a physiological process. In the elderly, loss of functional reserve in all organ system, regression in anabolic processes and increase in catabolic processes are observed s (1). The number of geriatric patients is also increasing in our country. Technological developments in anesthesia and surgery technics show that we will provide medical services to more elderly patients over time(2). Cystatin C is excreted only by the kidney (7, 8). Serum cystatin C level is not affected by body muscle mass, age and gender. The half-life is short. Because of all these features, it is thought to be more sensitive than creatinine in evaluating kidney functions (8,9). In this study, it was aimed to compare the effects of low flow and normal flow desflurane anesthesia applied in geriatric patients on postoperative liver and kidney functions and serum cystatin C levels.

NCT ID: NCT05406609 Completed - Anesthesia Clinical Trials

Cost Comparison Between General Anesthesia and Regional Anesthesia in Shoulder Operations

Start date: June 7, 2022
Phase:
Study type: Observational

Shoulder surgery can be done not only arthroscopy but also open technic. General or regional anaesthesia can be used at this surgery. Anaesthetic choice can be changed by comorbidity factors, patients or surgeons choice etc. At this study we aimed compare the general and regional anesthesia costs during operating room.

NCT ID: NCT05401526 Completed - Anesthesia Clinical Trials

Fluid Responsiveness in Prone Position

Start date: June 5, 2022
Phase:
Study type: Observational

We are planning to measure hemodynamic parameters (Heart Rate, Mean Arterial Pressure, Stroke Volume Index, Stroke Volume Variation, and Pulse Pressure Variation) and ventilatory parameters at four times (T1, T2,T3, and T4) during spinal operation at prone position. First measurement (T1, First baseline) will be performed in the prone position after performing tracheal intubation and confirming hemodynamic stability (defined as mean arterial pressure <10% for 3 minutes). After the T1 measurement, additional 5 cmH2O PEEP (Positive end-expiratory pressure) will be applied for 30 seconds which will be called as "short term low PEEP challenge (SLPC)". At the end of the SLPC and prior to PEEP lowering, T2 measurement will be performed and recorded. After the T2 measurement, PEEP will be decreased to the initial value (5 cmH2O) and three minutes later, a second baseline (T3) measurement will be performed. Thereafter, 500 ml isotonic saline will be loaded in 10 minutes. T4 measurement will be performed again three minutes after volume loading. All of the measurements will be completed before surgery start and surgical stimulus. Patients exhibiting an increase in stroke volume index more than 15% after fluid loading (between T3 and T4) will be classified as volume responders. Absolute pulse pressure variation change due to SLPC, Absolute Stroke volume variation change due to SLPC, stroke volume index percentage change due to SLPC, and stroke volume index percentage change after fluid loading will be calculated and compared. Our aim is to observe if short term low PEEP challenge has the ability to predict fluid responsiveness better than pulse pressure variation and stroke volume variation for patients operated in prone position.

NCT ID: NCT05386082 Completed - Anesthesia Clinical Trials

Anesthesia Core Quality Metrics Consensus Delphi Study

Start date: September 26, 2022
Phase:
Study type: Observational

To develop a ranked list of up to 20 metrics, which can be used to evaluate the quality of anesthesia, perioperative care, and acute pain management for adult inpatient non-cardiac surgical patients for use in quality improvement and quality assurance, research, and continuing medical education in the Canadian care context.

NCT ID: NCT05353218 Completed - Anesthesia Clinical Trials

Ultrasound-Guided Intermediate Versus Deep Cervical Plexus Block for Carotid Endarterectomy

Start date: June 7, 2022
Phase: N/A
Study type: Interventional

Cervical plexus blocks are regional methods used in carotid endarterectomy. Cervical plexus blocks consist of three blocks: superficial, intermediate and deep. These three blocks can be used alone or combined. The aim of this study is to evaluate the effectiveness of ultrasound-guided intermediate and deed cervical plexus block in patients undergoing carotid endarterectomy.

NCT ID: NCT05348980 Completed - Anesthesia Clinical Trials

Intramuscular Phenylephrine HCL for Prevention of Spinal Anesthesia Induced Hypotension

Start date: January 1, 2020
Phase: Phase 4
Study type: Interventional

Background: Spinal anesthesia (SA) is preferred over general anesthesia in Cesarean section (CS) due to its better safety profile but SA induced hypotension remains a big challenge for the clinical Anesthetist. Different methods including 15° left lateral table tilt, leftward uterine manual displacement, fluid pre-and co-loading have been used but drop in Systolic Blood Pressure (SBP) jeopardizing maternal and fetal well-being still occurs. Timely administered Phenylephrine HCL, an α-1 adrenergic agonist, is a recommended remedy. Subjects and methods: Sixty parturients of American Society of Anaesthesiologists (ASA) physical status 1 and 2, scheduled for elective CS under SA were enrolled in this prospective double-blinded study and randomly divided into two equal groups, P4 and P8. They received intramuscular (IM) Phenylephrine HCL 04 mg and 08 mg respectively before SA. Spinal block up to T6 was achieved with 12.5 mg 0.5% Bupivacaine HCl heavy. The incidence and intensity of hypotension, rescue doses of Phenylephrine HCL and any adverse event, were recorded. Data collected was analyzed using Epi lnfo ™ version 7.2.

NCT ID: NCT05346588 Completed - Depression Clinical Trials

THRIVE Feasibility Trial

THRIVE
Start date: September 29, 2022
Phase: Phase 3
Study type: Interventional

To evaluate the feasibility of a pragmatic, large scale, comparative effectiveness, randomized evaluation of patient experience of intravenous propofol versus inhaled volatile anesthesia.

NCT ID: NCT05345665 Completed - Anesthesia Clinical Trials

Comparison of Three Methods of Anesthesia to Achieve a Nerve Block Anesthesia.

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Evaluation of three methods for the realization of a neuronal blockade.

NCT ID: NCT05340751 Completed - Anesthesia Clinical Trials

The Effect of Hypotensive Anesthesia on Hemoglobin Levels During Total Knee Arthroplasty

Start date: January 1, 2014
Phase:
Study type: Observational

The current study investigates the effect of hypotensive anesthesia on patient hemoglobin levels during primary total knee arthroplasty. Considering that because of the tourniquet there is no blood loss during the first 60 minutes of the procedure changes in hemoglobin during the first 60 minutes should be primarily related to decrease in blood pressure and secondary to fluid loading during hypotensive anesthesia.