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Anemia, Iron Deficiency clinical trials

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NCT ID: NCT04016922 Not yet recruiting - Fetal Conditions Clinical Trials

The Effect of Maternal Iron Deficiency Anemia on Fetal Hemodynamic and Neonatal Outcome

Start date: July 2019
Phase:
Study type: Observational [Patient Registry]

This study will be conducted to show the effect of different degrees of maternal iron deficiency anemia on fetal hemodynamics and neonatal outcome and to evaluate the effect of treatment.

NCT ID: NCT04008147 Recruiting - Clinical trials for Gestational Diabetes

Hepcidin and Glucose Metabolism

Start date: July 3, 2019
Phase: N/A
Study type: Interventional

Gestational diabetes mellitus (GDM), defined as hyperglycemia with blood glucose values above normal but below those diagnostic of DM, and iron deficiency (ID) with or without anemia (IDA) are common during pregnancy. Both disease patterns are associated with an increased risk of complications during pregnancy and at delivery and may have a variety of negative effects on different aspects of child development. Thus, GDM and ID/IDA during pregnancy should be prevented. Whether iron supplementation with high oral doses acutely increases hepcidin during pregnancy, and whether this acute iron-induced increase in hepcidin decreases insulin sensitivity, is uncertain.

NCT ID: NCT03993288 Completed - Clinical trials for Mild and Moderate Iron-deficiency Anaemia

Study to Test the Hypothesis of Non-inferior Efficacy and Safety of Ferrum Lek® (Iron (III) Hydroxide Polymaltosate), 100 mg Chewable Tablets (Lek d.d., Slovenia), as Compared With MALTOFER® (Vifor S.A., Switzerland), in Subjects With Mild and Moderate Iron Deficiency Anemia.

Start date: June 27, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate non-inferiority for efficacy and safety of Ferrum Lek® (iron (III) hydroxide polymaltosate), 100 mg chewable tablets (Lek d.d., Slovenia), compared to MALTOFER® (Vifor S.A., Switzerland), in the treatment of patients with mild and moderate iron-deficiency anaemia.

NCT ID: NCT03991000 Terminated - Clinical trials for Cardiovascular Diseases

Iron in Patients With Cardiovascular Disease

iCHF-2
Start date: February 28, 2019
Phase: Phase 3
Study type: Interventional

It is now recognized that iron deficiency in cardiovascular disease contributes to impaired clinical outcome.

NCT ID: NCT03988712 Completed - Colorectal Cancer Clinical Trials

Measures to Increase the Effectiveness of Fast Track Colorectal Clinics for Iron Deficiency Anaemia.

Start date: April 1, 2018
Phase:
Study type: Observational

A retrospective cohort study was conducted from 2016-18 in a single busy district general hospital providing services to a population of 700,000 people. In the study, patients with true IDA (low MCV and ferritin) were found to be more likely to have Colorectal cancer compared to any other type of anaemia which confirmed the latest guidelines for management of IDA. Compared to symptoms, only the presence of a mass on abdominal examination and rectal examination was found to be more likely associated with cancer.

NCT ID: NCT03961074 Completed - Clinical trials for Iron Deficiency Anemia of Pregnancy

Iron Deficiency Anemia Among Chinese Pregnant Women: a Multi-center Prospective Cohort Study

IRONWOMEN
Start date: May 10, 2019
Phase:
Study type: Observational [Patient Registry]

Iron deficiency anemia during pregnancy, which may lead to adverse pregnancy outcomes, was a serious health problem in China. Various iron supplements used in different regions of China, however, the effects have not been well investigated. The objective of this study is to investigate the diagnosis, treatment and prognosis of iron deficiency and iron deficiency anemia in Chinese pregnant women.

NCT ID: NCT03957187 Recruiting - Atrial Fibrillation Clinical Trials

Prevalence and Clinical Associates of Iron Deficiency in Patients With Atrial Fibrillation

AID-AF
Start date: October 1, 2019
Phase:
Study type: Observational

To estimate the prevalence of iron deficiency (ID) in patients with atrial fibrillation

NCT ID: NCT03957057 Completed - Iron-deficiency Clinical Trials

Intravenous Iron Carboxymaltose, Isomaltoside and Oral Iron Sulphate for Postpartum Anemia

Start date: September 10, 2020
Phase: Phase 3
Study type: Interventional

Anemia affects between 20 and 50 % of women in the postpartum period. It is associated with several adverse health consequences, such as impaired physical work capacity, deficits in cognitive function and mood, reduced immune function and reduced duration of breastfeeding. Postpartum anemia has also been shown to be a major risk factor for postpartum depression and to significantly disrupt maternal-infant interactions. Iron deficiency is the principal cause of anemia after delivery. Oral iron supplementation with ferrous sulfate has been considered the standard of care with blood transfusion reserved for more severe or symptomatic cases. In the last decade, two new intravenous iron compounds have been registered for clinical use: ferric carboxymaltose (Iroprem®) and iron isomaltoside (Monofer®). No study to date compared efficacy of iron carboxymaltose to iron isomaltoside for treatment of postpartum anemia. The objective of the study is to compare efficacy of intravenous iron carboxymaltose to intravenous iron isomaltoside and oral iron sulphate for treatment of postpartum anemia.

NCT ID: NCT03944733 Withdrawn - Clinical trials for Iron Deficiency Anemia

Iron Status, Maternal Depressive Symptoms, and Mother-child Interactions

IDinteract
Start date: December 1, 2019
Phase: N/A
Study type: Interventional

This study aims to examine the relation between iron status and maternal-child interactions as well as maternal depressive symptoms in mothers from central Pennsylvania.

NCT ID: NCT03940430 Completed - Clinical trials for Iron Deficiency Anemia

Lactoferrin Versus Ferrous Sulfate in Management of Iron Deficiency Anemia Among Female Medical Ain Shams Students

Start date: September 10, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This study aims to compare the efficacy of lactoferrin versus iron supplementation versus two combined supplementation on iron deficiency anemia in female medical Ain Shams students by using iron profile.