Pain, Postoperative Clinical Trial
Official title:
Can we Predict Postoperative Analgesic Requirement by Intraoperative Nociception?
If the individual patient's pain is assessed and the amount of analgesic needed after surgery is predicted, appropriate injection of pain control and excessive injection of narcotic analgesic can be prevented. Therefore, investigators try to evaluate the degree of pain during surgery and the amount of analgesic use for management of postoperative pain.
Post-operative pain not only alleviates patient discomfort, but also delays recovery and thus
prolongs the hospital stay. There are many ways to control postoperative pain, but analgesic
infusion through venous route, patient controlled analgesia (PCA), especially narcotic
analgesics, is often used to control the infusion when needed. However, because PCA is based
on only age, weight, and underlying diseases, there are limitations in effective analgesia,
and excessive sedation due to excessive infusion. Therefore, if the individual patient's pain
is assessed and the amount of analgesic needed after surgery is predicted, appropriate
injection of pain control and excessive injection of narcotic analgesic can be prevented. The
noxious stimuli during surgery may have a negative effect on the healing process and surgical
outcome of the wound due to stress reaction and catabolism, secretion of pituitary hormone,
activation of the sympathetic nervous system, and immunological changes. Therefore, proper
analgesia is needed during general anesthesia. A non-invasive, non-invasive analgesic device
is currently available for Surgical pleth index (SPI) to assess the status of intraoperative
analgesia. SPI = 100- (0.3 * heart beat interval + 0.7 * photoplethysmographic pulse wave
amplitude) is automatically and continuously calculated from the waveform of peripheral
oxygen saturation.
In the postoperative pain prediction study with SPI, the SPI value at the end of the
operation was found to be proportional to the pain in the recovery room. However, only the
pain score immediately after the operation was confirmed in these studies. Therefore,
investigators try to evaluate the degree of pain during surgery and the amount of analgesic
use for management of postoperative pain.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05480111 -
The Role of Quadratus Lumborum Blocks Following Minimally Invasive Hysterectomy
|
Phase 4 | |
Completed |
NCT06129305 -
Erector Spina Muscle Distance From the Skin at Different Thoracal Elevations
|
||
Completed |
NCT04401826 -
Micro-surgical Treatment of Gummy Smile
|
N/A | |
Recruiting |
NCT04020133 -
the Role of Popliteal Plexus Block in Pain Management After Anterior Cruciate Ligament Reconstruction.
|
N/A | |
Completed |
NCT03023462 -
Efficacy of an Anterior Quadratus Lumborum Block vs. a TAP-block for Inguinal Hernia Repair
|
N/A | |
Completed |
NCT03652103 -
Efficiency of Erector Spinae Plane Block For Patients Undergoing Percutaneous Nephrolithotomy
|
Phase 4 | |
Completed |
NCT03546738 -
Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery
|
N/A | |
Withdrawn |
NCT03528343 -
Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy
|
Phase 1/Phase 2 | |
Terminated |
NCT03261193 -
ITM + Bupivacaine QLB vs. ITM + Sham Saline QLB for Cesarean Delivery Pain
|
Phase 3 | |
Completed |
NCT02525133 -
Phase 3 Study of Efficacy and Safety of the XaraColl® Bupivacaine Implant After Hernioplasty
|
Phase 3 | |
Completed |
NCT03244540 -
Regional Analgesia After Cesarean Section
|
Phase 4 | |
Enrolling by invitation |
NCT05316168 -
Post Operative Pain Management for ACL Reconstruction
|
Phase 3 | |
Recruiting |
NCT04130464 -
Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
|
Phase 4 | |
Enrolling by invitation |
NCT04574791 -
Addition of Muscle Relaxants in a Multimodal Analgesic Regimen for Analgesia After Primary Total Knee Arthroplasty
|
N/A | |
Completed |
NCT04526236 -
Influence of Aging on Perioperative Methadone Dosing
|
Phase 4 | |
Completed |
NCT04073069 -
Scalp Infiltration With Diprospan Plus Ropivacaine for Postoperative Pain After Craniotomy in Adults
|
Phase 4 | |
Recruiting |
NCT05351229 -
Intrathecal Morphine for Analgesia in Video-assisted Thoracic Surgery
|
Phase 4 | |
Enrolling by invitation |
NCT05543109 -
Ultrasound Guided Psoas Compartment Block vs Suprainguinal Fascia Iliaca Compartment Block
|
N/A | |
Completed |
NCT05346588 -
THRIVE Feasibility Trial
|
Phase 3 | |
Completed |
NCT04919317 -
Combination Dexamethasone and Bupivacaine Pain Control in Reduction Mammaplasty
|
Phase 2 |