Theory-Driven Manualized Approach to Improving New Learning and Memory in Healthy Aging and MCI

Aging Clinical Trial

Official title:

Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in Healthy Aging and Mild Cognitive Impairment

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06269939
• Other study ID #: R-1253-24
• Status: Not yet recruiting
• Phase: N/A
• Start date: March 1, 2024
• Est. completion date: March 30, 2025

Study information

• Verified date: February 2024
• Source: Kessler Foundation
• Contact: Nancy Moore
• Phone: 19733248450
• Email: nbmoore[@]kesslerfoundation.org
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in an aging population.

Description:

Memory enhancing techniques have been incorporated into an 8-session treatment protocol, Strategy Based Training to Enhance Memory (STEM), designed to teach participants about each of the techniques, train them on how to apply the techniques in daily life and practice their application to daily life memory demanding situations. The protocol includes teaching participants over age 60 how to restructure a memory demanding situation in order to make optimal use of the techniques.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 40
• Est. completion date: March 30, 2025
• Est. primary completion date: March 30, 2025
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• Inclusion Criteria:

• read and speak English fluently

Exclusion Criteria:

• prior stroke or neurological injury/disease (i.e. traumatic brain injury, Multiple Sclerosis, or Stroke).

• history of significant psychiatric illness (for example, bipolar disorder, schizophrenia, or psychosis).

• significant alcohol or drug abuse history (inpatient treatment).

• Benzodiazepines and steroid use

• Diagnosis of dementia

Related Conditions & MeSH terms

• Aging

Intervention

Behavioral:
• STEM
Memory technique training

Locations

Country	Name	City	State
United States	Kessler Foundation	East Hanover	New Jersey

Sponsors (1)

Lead Sponsor	Collaborator
Kessler Foundation

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Verbal Leaning task	Change in total score from Open-Trial Selective Reminding Test (OT-SRT)	Three points in time: pre-treatment, immediately following treatment, and 6- months after treatment is completed]
Primary	Participation in Everyday life	Change in total score from Participation Assessment with Recombined Tools	Three points in time: pre-treatment, immediately following treatment, and 6- months after treatment is completed]
Secondary	Functional Neuroimaging	Change in total scores from memory task during fMRI scan	Two points in time: pre-treatment, immediately following treatment