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NCT05309161 Clinical Trial

Efficacy Testing of Crassocephalum Rabens Extract Capsules

Aging Clinical Trial

Official title:
Efficacy Testing of Crassocephalum Rabens Extract Capsules

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05309161
Other study ID # 21-129-A
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date March 14, 2022
Est. completion date June 30, 2022

Study information
Verified date March 2022
Source Greenyn Biotechnology Co., Ltd.
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study is to investigate the improveing effects of the Crassocephalum rebens extract on skin conditions in normal people.

Recruitment information / eligibility
Status Completed
Enrollment 40
Est. completion date June 30, 2022
Est. primary completion date June 30, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 20 Years and older
Eligibility Inclusion Criteria: 1. Age over 20 years 2. Healthy people Exclusion Criteria: 1. Non-volunteer 2. Pregnant and lactating women 3. Hypersensitivity to the assigned product 4. Diagnosed with skin diseases, liver diseases, kinedy disease, and other severe diseases 5. Cosmetic, drug, or food allergies 6. Concurrent aesthetic treatments (e.g., intense pulse light, medical peelings, or laser therapy) 7. Aceepted aesthetic treatments one month ago before the study 8. Chronic sun exposure (over 3 hours/day) 9. The members of the research team

Study Design

Related Conditions & MeSH terms

Intervention

Dietary Supplement:
• Crassocephalum rabens extract
dosage: a capsule (180 mg)/day; duration: 1 month

Locations
Country Name City State
Taiwan Chia Nan University of Pharmacy & Science Tainan

Sponsors (2)
Lead Sponsor Collaborator
Greenyn Biotechnology Co., Ltd. Chia Nan University of Pharmacy & Science

Country where clinical trial is conducted

Taiwan, 

Outcome
Type Measure Description Time frame Safety issue
Primary Measurement of skin hydration Corneometer CM825 is used to measure the moisture of upper cheek (unit: Corneometer® unit) Week 0
Primary Measurement of skin hydration Corneometer CM825 is used to measure the moisture of upper cheek (unit: Corneometer® unit) Week 4
Primary Measurement of skin brightness Chroma Meter MM500 is employed to measure the brightness of upper cheek (unit: L* value (L* range: 0-100)). Week 0
Primary Measurement of skin brightness Chroma Meter MM500 is employed to measure the brightness of upper cheek (unit: L* value (L* range: 0-100)). Week 4
Primary Measurement of skin texture Visia® skin analysis system is used to measure the skin texture of full face (unit: number of fine lines) Week 0
Primary Measurement of skin texture Visia® skin analysis system is used to measure the skin texture of full face (unit: number of fine lines) Week 4
Primary Measurement of skin spots Visia® skin analysis system is used to measure the skin spots of full face (unit: number of spots) Week 0
Primary Measurement of skin spots Visia® skin analysis system is used to measure the skin spots of full face (unit: number of spots) Week 4
Primary Measurement of collagen content DermaLab® Series SkinLab Combo (Cortex) is employed to measure skin collagen content of upper cheek (unit: collagen density) Week 0
Primary Measurement of collagen content DermaLab® Series SkinLab Combo (Cortex) is employed to measure skin collagen content of upper cheek (unit: collagen density) Week 4
Primary Measurement of Crow's feet Visia® skin analysis system is used to measure the skin spots of full face (unit: number of Visia® skin analysis system is used to measure the skin spots of full face (unit: number of fine lines around eyes) Week 0
Primary Measurement of Crow's feet Visia® skin analysis system is used to measure the skin spots of full face (unit: number of Visia® skin analysis system is used to measure the skin spots of full face (unit: number of fine lines around eyes) Week 4
Primary Measurement of skin elasticity Cutometer® is used to measure the skin elasticity of upper cheek (unit: mm) Week 0
Primary Measurement of skin elasticity Cutometer® is used to measure the skin elasticity of upper cheek (unit: mm) Week 4
Primary Measurement of skin wrinkles Visia® skin analysis system is used to measure the skin wrinkles of full face (unit: number of wrinkles) Week 0
Primary Measurement of skin wrinkles Visia® skin analysis system is used to measure the skin wrinkles of full face (unit: number of wrinkles) Weeks 4
Primary Measurement of skin pores Visia® skin analysis system is used to measure the skin spots of full face (unit: number of pores) Week 0
Primary Measurement of skin pores Visia® skin analysis system is used to measure the skin spots of full face (unit: number of pores) Week 4
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