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Clinical Trial Summary

This study will evaluate changes in blood vessels around the heart (e.g., aorta and carotid arteries) and in the brain with the loss of female sex hormones (e.g., estrogen) during the menopause transition. The menopause transition is associated with declines in blood vessel function and increased risk for cardiovascular disease and Alzheimer's disease. Increasing evidence supports an early role for declines in blood vessel function and future development of Alzheimer's disease in aging men and women. This study will learn about the effects of changes in female sex hormones, such as estrogen, during the menopause transition on blood vessel around the heart and in the brain in women.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05057546
Study type Interventional
Source University of Colorado, Denver
Contact Lyndsey DuBose, PhD
Phone 720-848-5596
Email [email protected]
Status Not yet recruiting
Phase Phase 4
Start date October 1, 2021
Completion date September 30, 2024

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