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Age-related Differences in Response to Pituitary Stimulation Tests

Aging Clinical Trial

Official title:
Age-related Differences in the Response to a Combined Pituitary Stimulation Test With TRH, LHRH and ACTH

Clinical Trial Summary

The purpose of this study to age-related differences to the response of a combined pituitary stimulation test with TRH, LHRH and ACTH.

Clinical Trial Description

Participants will be recruited in three different age intervals: 18-45 years, 55-80 years and 80+ years. These participants will all undergo the same stimulation test with 0.1 mg LHRH, 0.2 mg TRH, and 0.25 mg ACTH (Synachten). The tests will be perfomed at the same time of day for all particpants (between 08:15 and 08:45) and participants will be fasting for the test. Blood samples will be taken just before and at 10, 20, 30, 45, 60, 90 and 120 minutes following the stimulation test. Serum from blood samples will be stored at -20 degrees until analysis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04572139
Study type Observational
Source Aalborg University Hospital
Contact Johannes R Jensen, Bsc. med
Phone 97665185
Email johannes.j@rn.dk
Status Recruiting
Phase
Start date September 23, 2020
Completion date December 31, 2024
View Details
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