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Cardiovascular Responses to Heat Waves in the Elderly

Aging Clinical Trial

Official title:
Heat Waves in the Elderly: Reducing Thermal and Cardiovascular Consequences

Clinical Trial Summary

The purpose of this study is to assess the cardiovascular responses of the elderly to heat wave conditions

Clinical Trial Description

Heat waves are lethal and cause a disproportionate number of deaths in the elderly relative to any other age group. It is important to note that such deaths are primarily cardiovascular, not hyperthermia itself, in origin. Nevertheless, we know relatively little about the effects of aging on cardiovascular function during actual heat wave-like conditions. The central hypothesis of this work is that the elderly exhibit greater cardiovascular stress during heat wave conditions. Aim 1 will test the hypothesis that recognized impairments in thermoregulatory capacity in the elderly will culminate in heightened cardiovascular stress during prolonged exposure to heat wave conditions. Comprehensive cardiovascular and thermal responses in the elderly, relative to younger adults, will be evaluated during exposure to two prolonged heat wave conditions: hot and humid (replicating the 1995 Chicago heat wave), very hot and dry (replicating the 2018 Los Angeles heat wave). The expected outcome from this body of work will re-shape our understanding of the consequences of aging on cardiovascular function during heat waves ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04538144
Study type Observational
Source University of Texas Southwestern Medical Center
Contact
Status Active, not recruiting
Phase
Start date January 19, 2021
Completion date August 31, 2026
View Details
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