Study of Microbiota in Longevity County, Yongfu

Aging Clinical Trial

— SoMiLY  

Official title:

Study of the Feature of Intestinal Microbiota and Its Role in Healthy Aging in Southern Chinese From a Longevity County, Yongfu

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04210934
• Other study ID #: 20170307
• Status: Completed
• Start date: May 22, 2016
• Est. completion date: May 31, 2016

Study information

• Verified date: December 2019
• Source: Beijing Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study is an observational study designed to adopt a cross-sectional study design. In the context of China's longevity town (East Asian population), Yongfu, Guangxi, the background of non-medical care and antibiotic use was explored, and the intestinal microecological balance increased with age and natural health. Longevity relationship. This study was completed using a household survey. Through routine clinical examinations and analysis of biochemical laboratory indicators, at the same time, a questionnaire for ADL(activities of daily living), cognitive function, and related elderly information was carried out on the elderly to comprehensively provide health information for each elderly. Based on the remaining stool samples and serum samples, the second-generation sequencing technology and other omics-based technologies were explored. No additional collection of human specimens and information is involved.

In addition, this study also hopes to explore the transmission rules of age-related bacteria in long-lived families, and the relationship with health phenotypes such as blood sugar, blood lipids, and cognitive function. Potential impact. In summary, this study will provide data support for exploring the relationship between healthy longevity and intestinal microecological balance based on the characteristic population of the longevity hometown.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 160
• Est. completion date: May 31, 2016
• Est. primary completion date: May 31, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 22 Years to 111 Years

Eligibility

Inclusion Criteria:

• Obtained informed consent signed by volunteer or guardian

• Local lived for more than 50 years

Exclusion Criteria:

• Subjects being treated with antibiotic in 3 months

• People who cannot cooperate with completing the survey

• Severe gastrointestinal disorders

Related Conditions & MeSH terms

• Aging
• Healthy Aging

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Beijing Hospital	BGI-Shenzhen

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Aging-related fecal microbiota annotation	Taxonomy of bacteria(family,genus,species),Gene of bacteria	0 week
Secondary	interface of microbiota and other biomarkers in aging and related conditions	to study the correlation between microbiota and circulating biomarkers, including metabolite, and the shifts in various aging and related conditions	0 week