Short-term Postural Training for Older Adults

Aging Clinical Trial

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Official title:

The Use of Neuro-cognitive Strategies to Power Generalization Effect After Short-term Postural Training for Older Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04137952
• Other study ID #: MOST 108-2314-B-006-071 -
• Status: Completed
• Phase: N/A
• Start date: August 1, 2019
• Est. completion date: December 30, 2022

Study information

• Verified date: June 2021
• Source: National Cheng-Kung University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Generalization refers to skill transfer under various working spaces following motor practice. The extent of generalization effect links causal to in-depth recognition of error properties during motor practice. Idiom says "imperfect practice makes perfect". It could be beneficial for the elderly to gain superior capacity of balance transfer skill under the short-term productive failure learning environments. In contrast to traditional visual feedback that uses error avoidance training to optimize target balance task, the present 3-year proposal is to propose three potential neuro-cognitive strategies to improve motor skill transfer following stabilometer training. The strategies are expected to enhance opportunities of error experience and motor exploration via modified visual feedback, underlying facilitations of attentional resource and error-related neural networks. In the first year, the neuro-cognitive strategy for balance practice is progressive augmentation of visual error size to improve balance skill transfer. In the second year, the neuro-cognitive strategy for balance practice is visual feedback with virtual uncertainness of motor goal. In the third year, the neuro-cognitive strategy for balance practice is stroboscopic vision. EEG and central of pressure will be processed with non-linear approaches. Graph theory will characterize EEG functional connectivity and brain network efficiency regarding to brain mechanisms for practice-related leaning transfer. Trajectories of central of pressure will be analyzed with stabilogram diffusion analysis to reveal behavior mechanisms for practice-related variations in feedback and feedforward process for error corrections.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 150
• Est. completion date: December 30, 2022
• Est. primary completion date: December 30, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• Age above 60 years old healthy older adults without a history of falls.

• Able to understand and give informed consent.

• The Mini-Mental State Examination test score above 25-30.

• Lower limb muscle strength is evaluated as G grade

• The corrected visual acuity was within the normal range.

Exclusion Criteria:

• Any known history of mental illness

• Any neuromuscular or degenerative neurological disease(ex:stroke?SCI?TBI...etc)

• Any known history of cerebral cerebellar disease or intracranial metal implants.

• Weak of hearing or wearing a hearing aid

Related Conditions & MeSH terms

• Aging
• Balance

Intervention

Behavioral:
• size of error visual feedback
The strategies are expected to enhance opportunities of error experience and motor exploration via modified visual feedback, underlying facilitations of attentional resource and error-related neural networks.

Locations

Country	Name	City	State
Taiwan	National Chen Kong University Hospital	Taian	Eastern District

Sponsors (2)

Lead Sponsor	Collaborator
National Cheng-Kung University Hospital	Ministry of Science and Technology, Taiwan

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	EEG graph analysis	Graph theory will characterize EEG functional connectivity and brain network efficiency regarding to brain mechanisms for practice-related leaning transfer.	through study completion, an average of 1 year
Secondary	stabilogram diffusion analysis of central of pressure	Trajectories of central of pressure will be analyzed with stabilogram diffusion analysis to reveal behavior mechanisms for practice-related variations in feedback and feedforward process for error corrections.	through study completion, an average of 1 year
Secondary	root mean sqaure error of stabilometer	The root-mean-square value of the tracking trajectory of stabilometer and the target signal.	through study completion, an average of 1 year