Resistance Exercise Training at Different Intensities

Aging Clinical Trial

Official title:

Resistance Exercise Training at Different Intensities in Healthy and Frail Older People: A Feasibility Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04053920
• Other study ID #: 236559
• Status: Completed
• Phase: N/A
• Start date: March 1, 2018
• Est. completion date: December 18, 2019

Study information

• Verified date: March 2020
• Source: University of Glasgow
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of the current study, therefore, is to determine the feasibility of recruitment and adherence to resistance exercise training interventions performed at low and high loads, to volitional muscular failure, in a trial population that includes both healthy and frail older people.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: December 18, 2019
• Est. primary completion date: December 18, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Over age of 65 years

Exclusion Criteria:

• Current participation in an exercise programme

• Exercise deemed unsafe by clinical team

Related Conditions & MeSH terms

• Aging
• Frailty
• Sarcopenia

Intervention

Behavioral:
• Low Load Resistance exercise
leg extension, leg press, leg curl and calf press
• High Load Resistance exercise
leg extension, leg press, leg curl and calf press

Locations

Country	Name	City	State
United Kingdom	GRI Clinical Research Facility	Glasgow

Sponsors (1)

Lead Sponsor	Collaborator
University of Glasgow

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Muscle strength	Knee extensor maximal torque during an isometric MVC	Change from baseline to 8 weeks
Secondary	Vastus lateralis muscle thickness	Measured via ultrasound	Change from baseline to 8 weeks
Secondary	Muscle strength	Knee flexor maximal torque during an isometric MVC	Change from baseline to 8 weeks
Secondary	One-repetition maximum	leg extension, leg curl, leg press and calf press	Change from baseline to 8 weeks
Secondary	Biomechanics during walking and stair climbing	Motion analysis	Change from baseline to 8 weeks
Secondary	Short performance physical battery test	SPPB - balance, walking pace and chair rise	Change from baseline to 8 weeks
Secondary	Quality of life measure	EQ-5D-5L questionnaire	Change from baseline to 8 weeks