Krill Oil and Muscle in Older Adults

Aging Clinical Trial

Official title:

Effects of Krill Oil Supplementation on Muscle Function in Older Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04048096
• Other study ID #: 200170067
• Status: Completed
• Phase: N/A
• Start date: March 7, 2018
• Est. completion date: March 10, 2020

Study information

• Verified date: November 2020
• Source: University of Glasgow
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is to determine the effects of krill oil supplementation on muscle mass in function in older adults. Half of the participants will receive krill oil supplements and the other half a placebo.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 102
• Est. completion date: March 10, 2020
• Est. primary completion date: March 10, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• BMI less than 35kg/m2

Exclusion Criteria:

• Diabetes

• severe cardiovascular disease

• seizure disorders

• uncontrolled hypertension (>150/90mmHg at baseline measurement)

• cancer or cancer that has been in remission <5 years

• ambulatory impairments which would limit ability to perform assessments of muscle function

• dementia

• taking medication known to affect muscle (e.g. steroids)

• have an implanted electronic device (e.g. pacemaker/defibrillator/insulin pump)

• on anticoagulant therapy

• allergies to seafood

• regular consumption of more than 2 portions of oily fish per week.

Related Conditions & MeSH terms

• Aging
• Sarcopenia

Intervention

Dietary Supplement:
• Krill Oil
Aker Biomarine Superba Krill Oil
• Placebo
Mixed vegetable oil

Locations

Country	Name	City	State
United Kingdom	Stuart Robert Gray	Glasgow

Sponsors (1)

Lead Sponsor	Collaborator
University of Glasgow

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in Muscle strength	knee extensor muscle strength	Change from baseline to 6 months
Secondary	Change in Grip strength	Grip strength	Change from baseline to 6 months
Secondary	Change in Muscle thickness	Vastus lateralis muscle thickness	Change from baseline to 6 months
Secondary	Change in Short performance physical battery test	SPPB	Change from baseline to 6 months
Secondary	Change in Body Fat	Measured by BIA	Change from baseline to 6 months
Secondary	Change in Lean Mass	Measured by BIA	Change from baseline to 6 months
Secondary	Change in Fasting glucose	Fasting glucose	Change from baseline to 6 months
Secondary	Change in Blood lipids	Blood lipids	Change from baseline to 6 months
Secondary	Change in CRP	CRP	Change from baseline to 6 months
Secondary	Change in Erythrocyte fatty acid profile	Erythrocyte fatty acid profile	Change from baseline to 6 months