Power During Functional Tasks in Older Adults

Aging Clinical Trial

Official title:

Power During Functional Tasks in Older Adults: Reliability, Reference Values and Relationship With Other Outcome Measurements Related to Sarcopenia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04019132
• Other study ID #: S62540
• Status: Completed
• Start date: January 20, 2020
• Est. completion date: March 1, 2022

Study information

• Verified date: May 2022
• Source: Universitaire Ziekenhuizen Leuven
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The primary aim of this study is to optimize the methodology to measure lower limb power in older adults, so that clinicians are able to detect functional problems in this population earlier.

Description:

Aging is associated with slower movement patterns, a higher fall risk and a restriction in functionality. This will lead to an increase in the number of dependent elderly and a high socio-economic burden. From the age of 40, a systematic loss of muscle mass and muscle force, also known as sarcopenia, will occur. In addition, performing daily tasks requires the production of muscle force at a certain speed. The product of force and speed, power, decreases even earlier and faster than muscle force.

This power is typically measured with specialized equipment, which limits the large-scale applicability. With the help of accelerometry there is the possibility to measure power during more functional tasks and movements, which benefits the applicability, but the reliability, reference values and link with other outcome measurements related to sarcopenia has to be investigated.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 284
• Est. completion date: March 1, 2022
• Est. primary completion date: March 1, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• Age >20

Exclusion Criteria:

• Unstable cardiovascular diseases

• Fever or acute infection

• Cognitive or physical malfunctioning that hinders the understanding or performance of tests and/or instructions

Related Conditions & MeSH terms

• Aging

Intervention

Diagnostic Test:
• Muscle function test
Body measurements, power and strength tests of the knee extensor muscle, handgrip strength, functional capacity tests, objective measurement of physical activity (subgroup of older adults, n=50)

Locations

Country	Name	City	State
Belgium	KU Leuven - Department of Movement Sciences	Leuven	Vlaams-Brabant

Sponsors (1)

Lead Sponsor	Collaborator
Universitaire Ziekenhuizen Leuven

Country where clinical trial is conducted

Belgium, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Lower limb muscle power during a stair climb test	The power (watt) needed to perform stair climbing is calculated using a 3D accelerometer (DynaPort MoveTest, McRoberts), worn at the back of the participant	1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Primary	Lower limb muscle power during a sit-to-stand test	The power (watt) needed to perform 5 sit-to-stand transitions and a 30 sec. sit-to-stand test is calculated using a 3D accelerometer (DynaPort MoveTest, McRoberts), worn at the back of the participant	1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Primary	Reliability of power measurements measured with a 3D accelerometer	Reliability of power measurements (watt) measured with a 3D accelerometer (DynaPort MoveTest, McRoberts) worn during functional activities (stair climbing, sit-to-stand test) three times within a period of 2 weeks	1 test moment of approximately 30 minutes, planned between September 2019 and July 2020
Primary	Rate of power (force-velocity) development	Participants perform a test protocol on a Biodex Dynamometer. The rate of power development (watt/s) is defined as the linear slope of the power-time curve and is measured from the onset of movement till peak power.	1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Primary	Handgrip strength	Handgrip strength (kg) evaluated with a Jamar dynamometer	1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Primary	Jumping height	Jumping height (in cm) measured during a standardized jump test	1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Primary	Physical activity	Objective measurement of physical activity in a subgroup of older participants (n=50) by means of accelerometry	1 week
Primary	Number of steps/stairs a day	Objective measurement of physical activity in a subgroup of older participants (n=50) by means of accelerometry	1 week
Secondary	Number of repetitions during a 30s sit-to-stand test	Number of complete sit-to-stand transitions in 30 sec.	1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Secondary	6min walk distance	The walk distance (in m) covered in 6 min.	1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Secondary	Balance	Number of seconds a participant can hold a tandem stand, a semi-tandem stand or with the feet together	1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Secondary	Maximal gait speed	The average speed to walk 3m as fast as possible (in m/s)	1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Secondary	Usual gait speed	The average speed to walk 4m at a usual pace (in m/s)	1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Secondary	Maximal isometric strength	Maximal strength (Nm) is measured by means of unilateral isometric knee-extensor tests on a Biodex Dynamometer	1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Secondary	Maximal isokinetic strength	Maximal strength (Nm) is measured by means of unilateral isokinetic knee-extensor tests on a Biodex Dynamometer	1 test moment of approximately 1 hour, planned between September 2019 and July 2020