Aging Clinical Trial
Official title:
The DART Study: Exercise Strategies to Improve Physical Function in Older Adults
This study evaluates the effect of three different exercise strategies on physical function in older adults. Participants will be randomly assigned to one of three exercise groups: resistance training, moderate-intensity continuous cycling on a stationary bicycle, and high-intensity interval training on a stationary bicycle.
This project is confronting age-related physical disability by optimizing exercise strategies
for older adults. Aerobic training is recommended to improve cardiorespiratory (heart and
lung) function, while strength training is recommended for muscular function. These exercise
effects are necessary for building healthier lives and reducing mortality and disability
risk, but most older adults who do exercise typically only perform one type of exercise. In
doing so they are missing a key component for healthy aging. This study will address whether
stationary-cycling high-intensity interval training results in both cardiorespiratory and
muscular improvements, and it will be the first controlled study comparing adaptations to
high-intensity interval, aerobic, and strength training in sedentary older adults.
It is unclear whether the lack of muscular adaptations to traditional aerobic training is due
to the low intensity/high volume model that is currently prescribed, and thus the central
hypothesize of the study is that stationary-cycling high-intensity interval training can
improve both cardiorespiratory and muscular function. To test this hypothesis, the
investigators will measure heart, lung, and muscle function, as well as physical performance
in sedentary older adults, before and after 12 weeks of supervised training using one of
three exercise strategies; stationary-cycling high-intensity interval training,
stationary-cycling moderate-intensity continuous training, or strength training. By comparing
the outcomes across these three groups, the investigators will be able to confirm if short
intervals of high-intensity exercise can elicit both cardiorespiratory and muscular benefits.
This work will demonstrate that older adults can improve their cardiovascular health and
muscular strength with a single exercise strategy. Establishing in detail the cardiovascular
and muscular benefits of this exercise can lead to the implementation of new and improved
exercise guidelines for cardiovascular health and reduced physical disability in older
adults. Incidentally, it will also provide a framework for future studies to investigate the
importance of intensity in exercise. At the end of this study the investigators will be able
to disseminate a new evidence-based exercise protocol that will address a significant barrier
to healthy aging.
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