Functional Mobility in the Elderly: Influence of Morphological, Neuromuscular and Training Parameters

Aging Clinical Trial

Official title:

Functional Mobility in the Elderly: Influence of Morphological, Neuromuscular and Training

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03206580
• Other study ID #: UFRGS 2.034.508
• Status: Completed
• Phase: N/A
• Start date: October 15, 2016
• Est. completion date: December 31, 2018

Study information

• Verified date: June 2024
• Source: Federal University of Rio Grande do Sul
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Life expectancy and elderly population are increasing. Health professionals try to provide longevity with good quality of life for this population, through the functional independence maintenance. In this context, physical exercise has an important role, specially the strength training. The ability to produce muscle strength is positively associated with the functionality and independence of older people. Different types of strength training can lead to different neuromuscular and functional gains. These types of interventions can help health professionals to determine characteristics of training for the elderly, aiming the maintenance of their functional independence. Thus, the purpose of this study is to determine the effects of a concentric strength training versus a concentric-eccentric strength training for knee flexors and extensors on structural, neuromuscular and functional parameters in older people, as well as to investigate the effect of a detraining period. Additionally, the investigators will try to identify which structural and neuromuscular parameters of lower limbs are better related to the functionality.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 11
• Est. completion date: December 31, 2018
• Est. primary completion date: December 31, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 65 Years to 85 Years

Eligibility

Inclusion Criteria:

• Male;

• 65 years of age or more;

• able to walk independently;

• not engaged in regular physical exercise.

Exclusion Criteria:

• Auditory, vestibular, visual and/or neuromusculoskeletal impairments that could influence the tests and the training;

• severe cognitive impairment;

• lower limb surgery;

• osteoporosis;

• lower limb pain.

Related Conditions & MeSH terms

• Aging

Intervention

Other:
• Concentric training
Subjects will be submitted to 8 weeks (16 sessions) of a concentric training for knee flexors and knee extensors. This training will be performed in an isokinetic dynamometer at 70% of the subject's maximal voluntary isometric contraction.
• Concentric-Eccentric training
Subjects will be submitted to 8 weeks (16 sessions) of a concentric-eccentric training for knee flexors and knee extensors. This training will be performed in an isokinetic dynamometer at 70% of the subject's maximal voluntary isometric contraction.

Locations

Country	Name	City	State
Brazil	Exercise Research Laboratory, School of Physical Education, Federal University of Rio Grande do Sul	Porto Alegre	Rio Grande Do Sul

Sponsors (1)

Lead Sponsor	Collaborator
Federal University of Rio Grande do Sul

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pennation angle of rectus femoris, vastus lateralis and biceps femoris, bilaterally.	Pennation angle at rest	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Thickness of rectus femoris, vastus lateralis and biceps femoris, bilaterally.	Muscle thickness at rest	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Fascicle length of rectus femoris, vastus lateralis and biceps femoris, bilaterally.	Fascicle length at rest	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Echo intensity of rectus femoris, vastus lateralis and biceps femoris, bilaterally.	Echo intensity determined from a gray scale analysis of the muscles at rest	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Countermovement vertical jump	Maximal vertical height in the countermovement jump	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Timed-up-&-go	Time to rise from a chair, walk 3 meters, turn, walk back and sit again	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Unipodal static balance	Range in anterior-posterior and medio-lateral center of pressure movement during unipodal evaluation during 30 seconds	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Gait speed	Gait speed for walking 10 meters at self-selected speed	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Stair ascent and descent time	Time to stair ascent and descent stairs	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	6-minutes walking test	The distance that the subjects can walk during 6 minutes	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Sit-to-stand	Maximal number of repetitions during 30 seconds	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Power of knee extensors and knee flexors	Power during maximal concentric and eccentric contractions	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Rate of torque production of knee extensors and knee flexors	Rate of torque production during maximal isometric contractions	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Strength of knee extensors and knee flexors	Maximal isometric strength	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Strength of knee extensors and knee flexors	Maximal concentric strength	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining
Primary	Strength of knee extensors and knee flexors	Maximal eccentric strength	First evaluation, change from first evaluation to baseline, change from baseline to 8 weeks of training, change from 8 weeks of training to 4 weeks of detraining and change from 4 weeks of detraining to 8 weeks of detraining