Technical Development of Multi-Parametric Renocerebral MRI

Aging Clinical Trial

Official title:

Technical Development of Multi-Parametric Renocerebral MRI

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02831335
• Other study ID #: 1603M85492
• Status: Recruiting
• Start date: July 1, 2024
• Est. completion date: December 31, 2025

Study information

• Verified date: January 2024
• Source: University of Minnesota
• Contact: Xiufeng Li, Ph.D.
• Phone: 6126258258
• Email: lixx1607[@]umn.edu
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of the study is to investigate the associations of the age-related changes in the brain, kidneys and cognitive performance in healthy adults by utilizing multiple anatomic and functional MRI methods along with a battery of cognitive tests.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 120
• Est. completion date: December 31, 2025
• Est. primary completion date: December 31, 2025
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 21 Years to 80 Years

Eligibility

Inclusion Criteria:

1. English-speaking as primary language

2. No hearing loss or uncorrected vision

Exclusion Criteria:

1. Lacking capacity to consent

2. Having known history of cardiovascular diseases (e.g., clinical stroke)

3. Having acute and chronic obstructive pulmonary disease

4. Having known history of renal diseases (e.g., acute kidney injury)

5. Having known history of cognitive disorder or psychiatric illness

6. Having known history of chemical dependence (e.g., alcohol and narcotics)

7. Being treated with stimulant medications, anticonvulsants, antihypertensives or ß-adrenergic blockers

Related Conditions & MeSH terms

• Aging

Intervention

Other:
• MRI
Perform MRI studies
• MRI
Perform MRI studies
• MRI
Perform MRI studies
• Group 4
Perform MRI studies

Locations

Country	Name	City	State
United States	Center for Magnetic Resonance Research	Minneapolis	Minnesota

Sponsors (1)

Lead Sponsor	Collaborator
University of Minnesota

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	MRI measured perfusion for each group	MRI measurements will be summarized for each group by using mean and standard deviation or standard error.	Baseline
Primary	MRI measured vascular reactivity for each group	MRI measurements will be summarized for each group by using mean and standard deviation or standard error.	Baseline
Primary	Cognitive performance for each group	The total cognitive performance scores will be summarized for each group by using mean and standard deviation or standard error.	Baseline