Functional Impact of a Memory Intervention Program

Aging Clinical Trial

Official title:

Functional Impact of a Memory Intervention Program

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02087137
• Other study ID #: 14-21
• Status: Completed
• Phase: N/A
• First received: March 12, 2014
• Last updated: January 12, 2016
• Start date: May 2014
• Est. completion date: October 2015

Study information

• Verified date: January 2016
• Source: Baycrest
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: Ethics Review Committee
• Study type: Interventional

Clinical Trial Summary

Normal aging is associated with decline in some aspects of memory, and this can be a risk factor for reductions in everyday functioning. The Baycrest Memory and Aging Program teaches positive adaptation to age-related memory changes, including strategies for minimizing the everyday impact of normal memory change and positive lifestyle change to maximize brain health. Prior research has shown that the Memory and Aging program is effective in increasing participants' knowledge about memory, use of memory strategies, and confidence in memory function, as well as adoption of healthier lifestyle practices and reduction in intention to use unneeded health care resources.

Although not one of the stated goals of the program, informal feedback from participants suggests that the educational content and skills training in the Memory and Aging Program has led some participants to change behaviours in ways that lead to significant improvements in their everyday functioning. For example, graduating participants often volunteer examples of how they have applied what they have learned to succeed in everyday memory tasks such as learning a new name or keeping track of future plans. Based on this participant feedback, it is hypothesized that the knowledge, skills, and confidence gained by Memory and Aging Program participants may lead to positive behaviour changes that, in turn, lead to improved everyday functioning. The present study will test this hypothesis using a randomized controlled pretest-posttest design.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 69
• Est. completion date: October 2015
• Est. primary completion date: October 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 50 Years to 90 Years

Eligibility

Inclusion Criteria:

• Age 50-90

• Available to participate in all testing and intervention sessions (located in Toronto, Canada)

Exclusion Criteria:

• health conditions with major effects on cognition, including a current or previous history of stroke, brain surgery, or diagnosed neurological disorder

• dependence in instrumental activities of daily living

• cognitive impairment, defined as performance below cutoff for cognitive impairment on a standardized cognitive test, the Telephone Interview for Cognitive Status (Brandt, Spencer, & Folstein, 1988).

• affective impairment, defined as performance below cutoff for depression on standardized depression screen, the Geriatric Depression Scale (Yesavage et al., 1983)

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Aging

Intervention

Behavioral:
• Memory and Aging Program

Locations

Country	Name	City	State
Canada	Baycrest	Toronto	Ontario

Sponsors (1)

Lead Sponsor	Collaborator
Baycrest

Country where clinical trial is conducted

Canada, 

References & Publications (10)

Brandt, J., Spencer, M., & Folstein, M. (1988). The Telephone Interview for Cognitive Status. Neuropsychiatry, Neuropsychology, & Behavioral Neurology, 1(2), 111-117.

Gordon J, Rockwood K, Powell C. Assessing patients' views of clinical changes. JAMA. 2000 Apr 12;283(14):1824-5. — View Citation

Kiresuk, T. J., Smith, A., & Cardillo, J. E. (1994). Goal attainment scaling: Applications, theory, and measurement. Hillsdale, NJ: Lawrence Erlbaum Associates.

Troyer AK, Häfliger A, Cadieux MJ, Craik FI. Name and face learning in older adults: effects of level of processing, self-generation, and intention to learn. J Gerontol B Psychol Sci Soc Sci. 2006 Mar;61(2):P67-74. — View Citation

Troyer AK, Rich JB. Psychometric properties of a new metamemory questionnaire for older adults. J Gerontol B Psychol Sci Soc Sci. 2002 Jan;57(1):P19-27. — View Citation

Troyer, A. K. (2001). Improving memory knowledge, satisfaction, and functioning via an education and intervention program for older adults. Aging, Neuropsychology, and Cognition, 8(4), 256-268.

Walker SN, Sechrist KR, Pender NJ. The Health-Promoting Lifestyle Profile: development and psychometric characteristics. Nurs Res. 1987 Mar-Apr;36(2):76-81. — View Citation

Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992 Jun;30(6):473-83. — View Citation

Watson D, Clark LA, Tellegen A. Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol. 1988 Jun;54(6):1063-70. — View Citation

Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1982-1983;17(1):37-49. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Change in memory knowledge as measured by Memory knowledge quiz (modified from Troyer, 2001).		Baseline, Week 8, week 14	No
Other	Change in self-perceived memory as measured by Multifactorial Metamemory Questionnaire (Troyer & Rich, 2002)		Baseline, 8 weeks, 14 weeks	No
Other	Change in prospective memory function (Prospective telephone-call task, Troyer, 2001; actual week, Rendell & Craik, 2001)		Baseline, 8 weeks, 14 weeks	No
Other	Change in name learning (Name-learning task, based on Troyer, Häfliger, Cadieux, & Craik, 2006)		Baseline, 8 weeks, 14 weeks	No
Primary	Change from baseline in healthy lifestyle behaviours as measured by Health Promoting Lifestyle Profile II (Walker, Sechrist, & Pender, 1987)		Baseline, Week 8, week 14	No
Primary	Change from baseline in memory strategy use as measured by the Memory Strategy Toolbox (modified from Troyer, 2001)		Baseline, Week 8, week 14	No
Primary	Attainment of individualized goals for (a) lifestyle change, (b) memory strategy use, and (c) functional outcomes of memory strategy use as measured by Goal Attainment Scaling (Gordon, Powell, & Rockwood, 2000; Kiresuk, Smith, & Cardillo, 1994)		Baseline, Week 8, week 14	No
Secondary	Change in positive and negative affect as measured by Positive and Negative Affect Schedule (Watson, Clark, & Tellegen, 1988)		Baseline, Week 8, week 14	No
Secondary	Change in general health status as measured by the RAND 36-Item Short-Form Health Survey (Ware & Sherbourne, 1992).		Baseline, Week 8, week 14	No
Secondary	General Self-Efficacy Scale (Schwarzer & Jerusalem, 1995)		Baseline, Week 8, week 14	No
Secondary	Prospective and Retrospective Memory Questionnaire (Smith, Della Sala, Logie, & Maylor, 2000)		Baseline, Week 8, week 14	No
Secondary	Self-report health status, lifestyle changes, attitudes about aging		Baseline, Week 8, week 14	No

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