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NCT00823589 Clinical Trial

Immune Status of Elderly Population Admitted in an Acute Geriatric Unit

Aging Clinical Trial

Official title:
Immune Status of Elderly Population Admitted in an Acute Geriatric Unit

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00823589
Other study ID # 2008 -21
Secondary ID
Status Completed
Phase N/A
First received January 14, 2009
Last updated February 24, 2014
Start date January 2009
Est. completion date February 2012

Study information
Verified date February 2014
Source Assistance Publique Hopitaux De Marseille
Contact n/a
Is FDA regulated No
Health authority France: Ministry of Health
Study type Interventional

Clinical Trial Summary

Ageing is associated with vulnerability against infections leading to increased morbidity with risk of death. Innate and adaptive immunities are altered with ageing responsible of deficits in immune response against pathogens and after vaccination, and favouring the elderly vulnerability against a new pathogen with increased bacterial, viral, and fungal infections.

If immunity has been widely studied in immunosenescence, there are few prospective, comparative studies with elderly ill patients. Moreover among these studies, pathologies are not well defined.

The main objective of our project is to compare the immune state of elderly hospitalised subjects in an acute geriatric unit to the immune state of elderly healthy subjects selected with strict criteria, in order to precise the impact of polypathology and of various pathologies on immunity state.

Recruitment information / eligibility
Status Completed
Enrollment 78
Est. completion date February 2012
Est. primary completion date February 2012
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 75 Years and older
Eligibility Inclusion Criteria:

- Subject of 75 or more years old, female or male

- Subject admitted in the service of short stay gériatrique of the hospital Holy Marguerite, whatever is the motive for admittance

- Subject not being under supervision(guardianship), nor guardianship

- Subject benefiting from a benefit system

- Subject having given its assent of participation or for which the reliable person gave her assent in the case of vulnerable person

Exclusion Criteria:

- Subject of less than 75 years old

- Subject refusing to participate in the study or for whom(which) the reliable person refuses the participation of the subject

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label

Related Conditions & MeSH terms

Intervention

Other:
• Blood test and clinical test
Blood test and clinical test

Locations
Country Name City State
France HOPITAL DE SAINTE MARGUERITE Service de Gériatrie Sud Marseille Paca

Sponsors (1)
Lead Sponsor Collaborator
Assistance Publique Hopitaux De Marseille

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary compare the immune state of elderly hospitalised subjects in an acute geriatric unit to the immune state of elderly healthy subjects 2 years No
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