Aging Clinical Trial
Official title:
Ameliorating Disability Through Power Training
Verified date | July 2010 |
Source | National Institute on Aging (NIA) |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Interventional |
The purpose of this study is to evaluate two types of exercise therapy designed to improve muscle power and mobility: weighted vest exercise vs. progressive resistance training.
Status | Completed |
Enrollment | 160 |
Est. completion date | September 2007 |
Est. primary completion date | September 2007 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 65 Years and older |
Eligibility |
Inclusion Criteria: - Community dwelling men and women aged 65 or older - Ability to provide informed consent - Impairment in physical performance, based on a score between 4 and 10 inclusive on the SPPB (Short Physical Performance Battery), which evaluates standing balance, walking speed, and chair-rise time - Score of 24 or greater on the Folstein mini-mental status exam - Exhibit independent stair-climbing ability Exclusion Criteria: - Unstable acute or chronic disease - Neuromusculoskeletal impairment interfering with independent stair climbing - Abdominal aortic aneurysm - Exertional angina - History of ventricular arrhythmia - Inguinal or abdominal hernia - Symptomatic valvular heart disease |
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | Spaulding Cambridge Outpatient Center | Cambridge | Massachusetts |
Lead Sponsor | Collaborator |
---|---|
National Institute on Aging (NIA) | Spaulding Rehabilitation Hospital PM&R |
United States,
Bean J, Herman S, Kiely DK, Callahan D, Mizer K, Frontera WR, Fielding RA. Weighted stair climbing in mobility-limited older people: a pilot study. J Am Geriatr Soc. 2002 Apr;50(4):663-70. — View Citation
Bean JF, Herman S, Kiely DK, Frey IC, Leveille SG, Fielding RA, Frontera WR. Increased Velocity Exercise Specific to Task (InVEST) training: a pilot study exploring effects on leg power, balance, and mobility in community-dwelling older women. J Am Geriatr Soc. 2004 May;52(5):799-804. — View Citation
Bean JF, Kiely DK, Herman S, Leveille SG, Mizer K, Frontera WR, Fielding RA. The relationship between leg power and physical performance in mobility-limited older people. J Am Geriatr Soc. 2002 Mar;50(3):461-7. — View Citation
Bean JF, Vora A, Frontera WR. Benefits of exercise for community-dwelling older adults. Arch Phys Med Rehabil. 2004 Jul;85(7 Suppl 3):S31-42; quiz S43-4. Review. — View Citation
Fielding RA, LeBrasseur NK, Cuoco A, Bean J, Mizer K, Fiatarone Singh MA. High-velocity resistance training increases skeletal muscle peak power in older women. J Am Geriatr Soc. 2002 Apr;50(4):655-62. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Leg power | |||
Primary | leg strength | |||
Primary | mobility | |||
Primary | endurance | |||
Primary | balance measured at baseline, 8 weeks, and 16 weeks | |||
Secondary | Disability |
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