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Age clinical trials

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NCT ID: NCT05208463 Completed - Pain Clinical Trials

Osteoarthritis Outcomes in Different Ages

Start date: January 1, 2019
Phase:
Study type: Observational

We aim to study if there are differences in outcomes between different age groups for persons with knee or hip osteoarthritis during treatment in digitally delivered exercise and education treatment.

NCT ID: NCT04973631 Completed - Gastric Cancer Clinical Trials

The Effects of Sex and Age Differences on Gastric Cancer : a Retrospective Study

Start date: May 2003
Phase:
Study type: Observational

Gastric cancer (GC) is more prevalent in males than in females. One of these differences could be the effect of sex hormones such as estrogens. However, few reports have been reported regarding sex and age differences of incidence and survival of GC. The aim of this study was to evaluate the effect of sex and age on the incidence and survival of GC. And we would like to further analyze single GC and synchronous multiple GC, EBV, etc.

NCT ID: NCT04686851 Recruiting - Cancer Clinical Trials

Predictive Value of Geriatric Oncology Screening and Geriatric Assessment in Older Patients With Solid Cancers

PROGNOSIS-RCT
Start date: November 1, 2020
Phase: N/A
Study type: Interventional

A Randomized Clinical Trial examining the effects of Comprehensive Geriatric Assessment as an add on to oncologic treatment. Participants included are cancer patients found eligible for oncologic treatment, age 70 or more, and screened frail with the Geriatric 8 screening tool.

NCT ID: NCT04644874 Completed - Cancer Clinical Trials

Geriatric Oncology Screening of Older Patients With Solid Cancers

PROGNOSIS-G8
Start date: June 3, 2020
Phase:
Study type: Observational

Older patients with cancer constitute a heterogeneous group with varying comorbidity; therefore, geriatric assessment with initial screening is recommended. The Geriatric 8 (G8) has been established as a promising screening tool. Currently, there are no guidelines for oncogeriatric screening in older cancer patients in Denmark. We hypothesize that by screening persons age 70 years or more with newly diagnosed cancer, with the G8, we can assess the prognostic value and identify a subgroup of patients who will benefit from a CGA. Aims: - Determine whether Danish cancer patients, with a G8 score of ≤14, experience poorer quality of life (QoL), receive less recommended standard cancer treatment, experience more treatment-related toxicity, stop treatment earlier, and experience shorter survival than patients with a G8 score >14. - Ascertain whether the standard G8 cut-off score of ≤14 is the most relevant cut-off score, with respect to treatment adherence, treatment-related toxicity, QoL, and survival, when focusing on the older Danish cancer patient population. - Establish whether the performance and prognostic value of the G8 can be strengthened through the addition of a functional measure, the 30-second chair stand test (30-CST), and/ or the handgrip strength test (HGST). - Evaluate the prognostic value of the modified Geriatric 8 (mG8) Methods: A prospective, descriptive study of all outpatients with newly diagnosed solid tumors at the Department of Oncology, Odense University Hospital, age 70 years or more. Patients will be screened with the G8, mG8, 30-CST, HGST, and QoL questionnaires at baseline with subsequent one-year follow-up, to determine the prognostic value of the G8 and the mG8. An initial two-month pilot study will help determine inclusion rates and highlight necessary practical adjustments to ensure optimal study participation. Baseline characteristics will be compared with descriptive statistics. Our primary endpoint; Global Health status/ QoL (EORTC QLQ-C30 & QLQ-ELD14), and secondary endpoints; treatment adherence, and treatment-related toxicity, will be assessed using logistical regression; while secondary endpoints; overall survival, cancer-specific survival, will be assessed using the Kaplan Meier analysis and Cox proportional hazard models. Post hoc diagnostic performance analysis will be conducted to determine the optimal G8 cut-off and whether functional measures (30-CST and HGST) can enhance screening accuracy.

NCT ID: NCT04141722 Recruiting - Sleep Clinical Trials

Age-Related Changes in Sleep-Dependent Emotional Memory

Start date: December 11, 2018
Phase: N/A
Study type: Interventional

Memory influences emotional well being. Research has shown that having a negative emotional bias contributes to both emotion dysregulation and depression. Conversely, reactivating positive memories has been shown to reduce stress and symptoms of depression. In young adults, sleep is widely implicated in emotional processing, including consolidation of emotional memories. Evidence suggests that aging is associated with changes in emotion, including a positive memory bias and enhanced emotional well-being. These changes have been termed the "age-related positivity effect." However, the influence of sleep on these measures has not been investigated in healthy older individuals. The objective of this research is to understand the role of sleep in emotional memory consolidation and emotional well-being across adulthood. We hypothesize that sleep contributes to the age-related positivity effect in memory and affect. Our alternative hypothesis is that age-related decreases in sleep are responsible for reduced emotional memory processing over healthy aging.

NCT ID: NCT03507309 Active, not recruiting - Clinical trials for Acute Coronary Syndrome

National Institute for Health Research (NIHR) Health Informatics Collaborative Troponin Study

NHIC-Troponin
Start date: January 2016
Phase:
Study type: Observational [Patient Registry]

The NHIC Cardiovascular Project is an observational, multi-centre and longitudinal study of clinical data from collaborating hospitals. A dataset of the longitudinal record for patients who presented with a suspected acute coronary syndrome, characterised by the request of a troponin test, has been developed (NHIC-Troponin Study).

NCT ID: NCT03361904 Completed - Colon Cancer Clinical Trials

Colonoscopic Adenoma and Advanced Neoplasia Detection Rates According to Age

Start date: January 1, 2016
Phase: N/A
Study type: Observational [Patient Registry]

Current recommendations for colonoscopy screening programs usually involve patients older than 50 years of age. However, little is known about polyp or adenoma detection rates under 50. We compared these detection rates according to age in a large series of patients in common practice. Methods: All colonoscopies performed in 2016 in our unit were prospectively recorded. We determined adenoma detection rate (ADR), polyp detection rate (PDR), mean number of polyps (MNP), and advanced neoplasia detection rate (ANDR).

NCT ID: NCT03237598 Completed - Metabolic Syndrome Clinical Trials

Gender Difference of Metabolic Syndrome and Its Association Between Dietary Diversity at Different Ages

Start date: January 1, 2009
Phase: N/A
Study type: Observational

With the development of economics in China, the dietary diversity got higher. Meanwhile, the prevalence of metabolic syndrome (MetS) raised up as well. To investigate the gender difference of getting MetS and its various associations with dietary diversity at different ages.Data of adults(n=4308) aged 18+ y with three consecutive 24-h recalls and complete co-variates information were extracted from Chinese Nutrition and Health Survey in 2009. Modified Dietary Diversity Score (DDS) was adopted to capture the diversity of diet. MetS was defined by the harmonized criteria. Multivariable adjusted logistic regression was carried out to detect the association between DDS and MetS and its components for young, middle aged and elderly adults by a cross-sectional study. More detailed information can be found in Pubmed,PMID: 24341753 (The China Health and Nutrition Survey, 1989-2011.).

NCT ID: NCT02195778 Active, not recruiting - Adult Clinical Trials

Assessment of Health Literacy Among Adult Patients in the United Arab Emirates to Facilitate Clinical Trials Recruitment.

LIT
Start date: June 2013
Phase: N/A
Study type: Observational [Patient Registry]

Health Literacy is the ability to understand health information and to use that information to make good decisions about health and medical care. Health informatin can overwhelm even people with advanced literacy skills. About one third of the adult population in the United States has limited health literacy.

NCT ID: NCT02190864 Unknown status - Gender Clinical Trials

Patient-Defined Treatment Success and Preferences in Stage IV Lung Cancer Patients

Start date: December 2013
Phase: N/A
Study type: Observational

Our long-term goal is to integrate non-small cell lung cancer patient treatment preferences into clinical treatment planning.