Clinical Trials Logo

Affective Symptoms clinical trials

View clinical trials related to Affective Symptoms.

Filter by:

NCT ID: NCT03796247 Completed - Multiple Sclerosis Clinical Trials

Alexithymia Frequency and Interhemispheric Transfer in Patients With a First Demyelinating Event

ALEXCIS
Start date: May 2, 2011
Phase:
Study type: Observational

Prevalence of alexithymia in multiple sclerosis (MS) is closed to 50% but is unknown in clinically isolated syndrome (CIS).The present study sought to characterize alexithymia in CIS patients and his link between psycho behavioral and cognitive disturbances. In this context, the objectives of the present study were to (a ) define the prevalence of alexithymia in CIS patients, (b ) to study this relation between psycho behavioral and cognitive disorders frequently encountered in MS.

NCT ID: NCT03450135 Completed - Stress Clinical Trials

Neurophysiology, Estrogen, and Stress Exposure in the Emergence of Depression in Adolescent Girls

EVOLVE
Start date: February 25, 2018
Phase:
Study type: Observational

The prevalence of adolescent depression is steadily rising in the U.S., especially among adolescent girls. Currently 20% of adolescent girls experience major depression compared with 6% of boys (National Institute of Mental Health, 2016). The profound gender disparity in depression that emerges at puberty, but not before, implicates a role of ovarian steroid hormones in promoting affective (mood) symptoms in adolescent girls. In addition to dramatic physical maturation and a rapidly changing reproductive hormone environment at puberty, adolescence is also a time of exposure to substantial psychosocial stress, particularly in girls. It is well documented that stress interferes with the maturation of neurodevelopmental trajectories and is a critical precipitating factor in the pathway to psychopathology. However, the neuropathophysiological mechanisms linking stress exposure and sensitivity to ovarian hormone fluctuations at puberty to the onset and maintenance of depression symptoms in adolescence have yet to be elucidated, and is the purpose of this research.

NCT ID: NCT03443206 Completed - Clinical trials for Adolescent - Emotional Problem

Loves Company: Combatting Emotional Disturbance in the Digital Age

Start date: June 20, 2020
Phase: N/A
Study type: Interventional

The goal of this study is to determine whether a community-based website that is intended to provide support for adolescents experiencing psychological distress can improve members' mental health outcomes. The investigators want to understand if a digital platform can help young people who are suffering and may be unlikely to access more traditional forms of mental health services.

NCT ID: NCT03442439 Completed - Developmental Delay Clinical Trials

Stamford Group Family Nurture Intervention

Start date: January 31, 2018
Phase: N/A
Study type: Interventional

The purpose of this current study is to investigate the efficacy of a group model of Family Nurture Intervention in ameliorating behavioral problems in preschool-aged children. The behavioral, neurobiological and clinical insights gained from this project may eventually lead to better treatment of emotional, behavioral, and developmental disorders. The investigator hypothesizes that the children who are treated with Family Nurture Intervention (FNI), which incorporates interactive touch with vocal soothing, and family practice in comforting, will show increased emotional connection and mother child co-regulation with better results in the outcome measures in the short term and long term.

NCT ID: NCT03414463 Completed - Clinical trials for Traumatic Brain Injury

Training to Reconnect With Emotional Awareness Therapy

TREAT
Start date: May 8, 2018
Phase: N/A
Study type: Interventional

To decrease emotional self-awareness deficits and improve emotional self-regulation, particularly anxiety, anger, depression, and positive affect, through the treatment of alexithymia.

NCT ID: NCT03348813 Completed - HIV Clinical Trials

HIV/STI Prevention Among Black Adolescents With Mental Illnesses (Project GOLD)

Start date: August 1, 2014
Phase: N/A
Study type: Interventional

Despite advances in HIV/sexually transmitted infection (STI) prevention, Black youth account for the largest number of new HIV infections among heterosexual youth. Having a mental illness contributes to HIV/STI risk among heterosexually active Black youth, as some use sex as a means to manage psychological distress, regulate emotions and receive validation or acceptance. Current intervention models focus on cognitive-behavioral strategies to reduce risk among adolescents; however, these approaches in isolation do not address the psychopathology that further potentiates risk behaviors among adolescents with mental illnesses. This randomized controlled trial evaluated the effects of "Project GOLD", a theoretically-driven, gender and culturally relevant, developmentally and psychologically appropriate HIV/STI risk reduction intervention on the sexual behaviors of Black male and female adolescents in Philadelphia (aged 14-17). In addition to evidence-based HIV/STI preventions strategies (e.g., role playing), Project GOLD includes unique emotion regulation content to address the relationship between psychological distress and HIV/STI risk behaviors. The research team approached and screened 704 adolescents. Eighty-two participated in the elicitation research activities (e.g., focus groups, intervention dress rehearsal). Another 173 underwent a structured demographic and mental health diagnostic interview to determine RCT eligibility. Project GOLD was then tested with 108 Black youth in comparison to a general health promotion control condition (intervention n = 52; control n = 56). Youth who were not in psychiatric treatment were also included, as the investigators hypothesized that they would also benefit from the targeted psychoeducational content; post-hoc analyses examined differences in the intervention effects based on whether or not youth were in psychiatric treatment. The intervention had high feasibility and acceptability. These findings underscore the need to encourage HIV/STI testing and risk reduction efforts among Black youth, including those with mental illnesses.

NCT ID: NCT03336827 Completed - Breast Cancer Clinical Trials

Improving Emotion Regulation at the End of Breast Cancer Treatment

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The end of treatment marks the beginning of a challenging period for breast cancer patients. While this period often provokes a sense of relief, it can also be a source of apprehension and vulnerability regarding the future. Patients may be brought to feel contradictory thoughts and emotions impacting their quality of life such as anxiety linked to uncertainty and fear of cancer recurrence. In order to accompany breast cancer patients during this transition period and to address these emotional difficulties, the Institut Jules Bordet has launched an 8-session psychological multi-component group intervention. Its objective is to bring patients tools and competencies (e.g., hypnosis, treatment of intrusive thoughts, learning to cope with uncertainty, attention reorientation toward positive thoughts) to promote emotion management and well-being.

NCT ID: NCT03312673 Completed - Asthma Clinical Trials

Asthma, Smoking, Emotional Deficits

ASTADEM
Start date: November 22, 2017
Phase:
Study type: Observational

The objective of the study is to determine whether poor control of asthma is related to an emotional deficit such as alexithymia. The hypothesis is that there is a correlation between the severity of asthma, its control, and the degree of emotional deficits.

NCT ID: NCT03183947 Completed - Depression Clinical Trials

Symptom Based Treatment Affects Brain Plasticity - Cognitive Training in Patients With Affective Symptoms

APIC-II
Start date: August 29, 2017
Phase: N/A
Study type: Interventional

The aim of the study is the examination of brain plasticity on on affective symptoms after neuromodulation with fMRI (functional magnetic resonance imaging) neurofeedback. During the fMRI neurofeedback training, patients with depression as well as patients with schizophrenia are trained to consciously regulate the activity of areas which are associated with the cognitive reappraisal of emotional stimuli.The aim is to improve the patients' subjective emotional processing and perception in everyday life as well as to investigate the impact of neurofeedback on resting-state networks in the brain. Healthy participants will be investigated as control group.

NCT ID: NCT03092700 Completed - COPD Clinical Trials

Pulmonary Rehabilitation, Dyspnoea and Emotional Cognition in COPD

READ-COG BPCO
Start date: April 5, 2017
Phase:
Study type: Observational

To evaluate whether pulmonary rehabilitation improves emotional cognition, using facial emotions recognition and smile production, by improving the emotional dimension of dyspnoea in patients with chronic obstructive pulmonary disease (COPD).To evaluate whether pulmonary rehabilitation improves emotional cognition, using facial emotions recognition and smile production, by improving the emotional dimension of dyspnoea in patients with chronic obstructive pulmonary disease (COPD).