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Adolescents clinical trials

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NCT ID: NCT02561780 Completed - Mental Disorders Clinical Trials

Impact of a Mental Health Curriculum for High School Students on Knowledge and Stigma

Start date: October 2011
Phase: N/A
Study type: Interventional

This study examines the effectiveness of a school based mental health literacy intervention for high school students, on improving mental health knowledge and reducing stigma. Twenty-four high schools in the regional area of Ottawa, Canada were randomly assigned to either the curriculum or control condition at a two to one ratio. The educational curriculum was integrated within grade 11 and 12 Provincial "Healthy Living" courses, delivered by teachers, and replaced existing educational content on mental health.

NCT ID: NCT01558973 Completed - Alcoholism Clinical Trials

FMRI of Stress and Addictive Disorders

Start date: August 2005
Phase: N/A
Study type: Observational

The purpose of this study is to explore whether frontal brain activation in response to stress varies as a function of the presence or extent of early trauma and whether or not this effect is greater in women compared to men. To examine the effect of stress on thinking and remembering. To examine the separate and interactive effects of stress, addiction, withdrawal, and genetics; and to examine fMRI brain activation associated with stressful, reward-related-cue and neutral/relaxing audiotaped scripts,visual images and emotional video clips in addicted individuals and in healthy controls.

NCT ID: NCT01379924 Completed - Adolescents Clinical Trials

Young Parents Program, Project Connect

YPPProCon
Start date: September 2007
Phase: N/A
Study type: Interventional

1. Specific Aims 1. To evaluate the effects of life skills/parenting groups that are embedded within a comprehensive multidisciplinary clinic for adolescent parents (the Young Parents Program), using a randomized control design. Specifically, the effect of group participation on the following adolescent parent outcomes will be investigated: - Parenting attitudes and skills including empathy, non-violent discipline, role appropriateness and developmentally appropriate expectations. - Skills of daily living, social relationships, and work/study at follow-up, as measured by the Ansell-Casey Life Skills Assessment Scale. - Depression and perceived social support using the CESD-C and Duke Social Support scale. - Repeat pregnancy rates at 12 and 24 months after first delivery. 2. To evaluate the overall Young Parents Program service delivery as required by the Office of Adolescent Pregnancy Programs (project funder) using a cross cutting evaluation of health services utilization, social needs and work/educational outcomes.

NCT ID: NCT01086670 Completed - Cerebral Palsy Clinical Trials

Physical, Functional and Neural Effects of Two Lower Extremity Exercise Protocols in Children With Cerebral Palsy

Start date: March 30, 2010
Phase: Phase 1/Phase 2
Study type: Interventional

Background: - Many people who have cerebral palsy (CP) have spastic diplegia, which affects the legs and causes difficulty with leg movement and walking. Research has shown that exercise can help those with CP learn to move their arms better, but more research is needed to determine whether exercise programs can improve leg movements in people with CP. - Walking on a treadmill with the help of a physical therapist has improved the treatment outcomes of some individuals with spinal cord injuries. Many children with CP already have physical therapy but still have trouble with walking and leg coordination. Two other kinds of exercise machines, a stationary bicycle and an elliptical machine, used in the home, may be able to help children with CP walk better and move their legs better. Objectives: - To see how children with cerebral palsy (CP) move their legs differently from children without CP. - To see if an exercise program can improve leg coordination in children with CP. Eligibility: - Children between 5 and 17 years of age who either have spastic diplegia CP or are healthy volunteers. Design: - Children who are able and willing will have magnetic resonance imaging (MRI) scans at the start and the end of the study. - During Part I of the study, participants will demonstrate their leg and muscle function with the following tests: - Measurement of leg size and movement - Combined camera motion study and electrical impulse evaluation to assess how well the participant walks (with or without an assistive device, as needed) - Leg movement tests on an exercise bicycle and elliptical machine - Tests of leg muscle strength, stiffness, and effectiveness - Ultrasound scans of leg muscle - Parents of participants will complete computer-based questionnaires about their child s motor abilities. - A smaller group of participants will continue to Part II of the study, which involves regular exercise of 20 minutes a day, 5 days a week, for 3 months, on a stationary bicycle or elliptical trainer. Half of the group will start this exercise program immediately after the first part of the study, while the other half will wait 3 months before beginning the exercise program. - During Part II, participants will return to the clinical center for two more sets of the tests and evaluations performed in Part I.

NCT ID: NCT00623493 Completed - Adolescents Clinical Trials

Detecting Risk of Suicide in a Pediatric Emergency Department

Start date: February 7, 2008
Phase:
Study type: Observational

Objective: The ultimate goal of this project is to enhance the capacity of non-mental health clinicians working in an Emergency Departments (ED) to recognize and initiate further evaluation of children and adolescents at risk for suicide. Aim 1: To re-validate the Risk of Suicide Questionnaire (RSQ), a screening tool that assists non-psychiatric clinicians in rapidly detecting suicide risk in pediatric patients, in a pediatric ED mental health population in the Children s National Medical Center (CNMC) ED. Aim 2: To determine the utility of a suicide screening tool, a revised version of the Risk of Suicide Questionnaire, to detect suicide risk in pediatric patients presenting to the CNMC ED for non-mental health reasons. Study population: The study population includes all patients admitted to the CNMC Emergency Department, ages 10 to 21, during the data collection weeks of the study period. Both patients admitted for mental health and non-mental health reasons will be included in the study. Design: This will be a prospective instrument development /validation study. During a designated study week, all mental health patients and a random subset of non-mental health patients admitted to the CNMC ED will be approached after their triage assessment. Following informed consent and assent, a 17-item suicide assessment tool created for this research project (RSQ-Revised), as well as a brief background questionnaire will be administered. These questions will be validated against a gold standard suicide assessment questionnaire, which will be administered to the subjects directly after the RSQ-Revised. The study aims to develop a brief suicide screening tool to be used at triage for all patients entering the ED. Measures Measures include the proposed 17-item screening questionnaire and a gold standard assessment of suicidal ideation in adolescents, the Suicide Ideation Questionnaire (SIQ).

NCT ID: NCT00571311 Completed - Adolescents Clinical Trials

Parental Permission and Adolescent Assent and Decision-Making in Clinical Research

Start date: December 10, 2007
Phase:
Study type: Observational

This study will evaluate how adolescents enrolled in clinical research and their parents: - Understood the study information presented before they agreed to participate - Made decisions about enrolling in the study - Experienced the process of assent and consent - Perceive the experience of participating in research The study will determine how adolescents and their parents evaluate risk and benefit, what information they use in making their research enrollment decisions, and how these decisions are made. In recent years the medical community and the federal government have increasingly recognized the need to conduct pediatric research. Several initiatives have resulted in an expanding number of studies that include children. With more pediatric research comes the need to ensure that protections for the rights and safety of children enrolled in research are performing well. Adolescent patients between 13 and 18 years of age who are enrolled in a research study at the NIH involving cancer, diabetes mellitus, vaccines, obesity, bipolar disorder, and HIV, as well as healthy adolescent controls, may be eligible. One parent of each adolescent also participates. Participants are interviewed at the NIH Clinical Center. Each interview will last about 30 minutes and consists of questions in the following areas: - Demographics (age, sex, ethnicity, education, socioeconomic status, etc.) - Brief medical history of the adolescent - Experience and satisfaction with the parental permission/assent process - Motivations for participating in clinical research - Decision-making process - Willingness to accept certain types and levels of hypothetical risks in a study, including those of side effects and invasive procedures - Willingness to enroll with different chances of possible benefit - Comparison with other activities - General understanding of research