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Adenoma clinical trials

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NCT ID: NCT05445570 Completed - Colorectal Cancer Clinical Trials

Non-invasive Identification of Colorectal Cancer and Adenomas in Early Stages

NICE
Start date: May 13, 2022
Phase:
Study type: Observational

The NICE study is a prospective, multi-site study to train and validate a blood-based, glycoproteomic test for the early detection of advanced adenoma and colorectal cancer by collecting blood samples and associated relevant clinical information from average-risk participants who undergo routine screening colonoscopy as well as participants undergoing colonoscopy for surveillance or diagnostic indications

NCT ID: NCT05422820 Completed - Colorectal Cancer Clinical Trials

The Argentina Brief Colonoscopy Difficulty Score (ABCD)

ABCD
Start date: July 1, 2022
Phase:
Study type: Observational [Patient Registry]

Colonoscopy completion by caecal intubation seldom represents a significant effort for the endoscopist. In this situation, additional techniques are necessary to achieve this goal: patients' manual abdominal compression, postural changes, and endoscopist relay. To date, no tool allows colonoscopy technical difficulty grading. This study pursues to describe the frequency of additional techniques for caecal intubation in a large sample of Argentinians in different centres who undergo colonoscopy for attending purposes, to develop a novel score for assessing colonoscopy technical difficulty.

NCT ID: NCT05389397 Completed - Polyp of Colon Clinical Trials

De-implementation of Outdated Colonoscopy Surveillance Interval Recommendations Among Patients With Low-risk Adenomas

DESIRE
Start date: May 12, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effectiveness of three standard of care outreach approaches (i.e., mailed letter, secure message, and telephone call) on patient adoption of the new 10-year colonoscopy surveillance interval recommendation for a random sample of health plan members who have a now-outdated 5-year surveillance interval due to a finding of 1-2 small adenomas at their prior colonoscopy. The primary study endpoint is the proportion of patients in each outreach arm who adopt the new 10-year colonoscopy surveillance interval.

NCT ID: NCT05361083 Completed - Clinical trials for Adrenocortical Carcinoma

First-in-human Evaluation of [18F]CETO

Start date: September 1, 2019
Phase: Early Phase 1
Study type: Interventional

Purpose of this clinical phase 1 trial was to determine if para-chloro-2-[18F]fluoroethyletomidate positron emission computed tomography ([18F]CETO-positron emission computed tomography(PET)/computed tomography(CT)) can be used in diagnostics of adrenal tumors and if the biochemical/pharmacological states conditions in humans with various illnesses, compared to healthy humans, such as the radio tracer is suitable?

NCT ID: NCT05275556 Completed - Colon Polyp Clinical Trials

Gastroenterology Artificial INtelligence System for Detecting Colorectal Polyps (The GAIN Study)

GAIN
Start date: March 1, 2022
Phase: N/A
Study type: Interventional

This is a prospective, multicenter, randomized controlled study to evaluate the effect of the Computer-Assisted Detection (CADe) Device on Adenomas Per Colonoscopy and Positive Percent Agreement for routine colonoscopies. The control arm is colonoscopy performed with High Definition White Light Endoscopy (HD-WLE) per standard of care. The intervention arm is colonoscopy performed with HD-WLE per standard of care plus the Computer-Assisted Detection (CADe) Device.

NCT ID: NCT05236790 Completed - Colorectal Adenoma Clinical Trials

Evaluation of CAD-EYE/SCALE-EYE for Detection, Classification, and Measurement of Colorectal Polyps: a Prospective Study

Start date: June 20, 2022
Phase: N/A
Study type: Interventional

The investigators hypothesize that the clinical implementation of an AI system is an optimal tool to monitor, audit and improve the detection and classification of polyps during colonoscopy. The purpose of this prospective clinical cohort study is to evaluate the performance of the SCALE-EYE virtual scale for measuring polyp size when used during live colonoscopies. The investigators also wish to evaluate CAD-eye for detection and classification of polyp histology. It is hypothesized that CAD-eye and SCALE-EYE can function in real-time practice with high accuracy.

NCT ID: NCT05178095 Completed - Clinical trials for Gastrointestinal Neoplasms

Artificial Intelligence in Colonic Polyp Detection

Start date: September 30, 2020
Phase: N/A
Study type: Interventional

A randomized, controlled study investigating the potential benefits of artificial intelligence (AI) in the detection of colonic polyps during outpatient colonoscopy. Randomization between the use of AI and no AI is performed before the study procedure.

NCT ID: NCT05089071 Completed - Colonoscopy Clinical Trials

Effect of Two Colonoscopy AI Systems for Colon Polyp Detection

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Computer-aided detection (CADe) systems have been actively researched for polyp detection in colonoscopy. The investigators aim to identify the effect of two CADe systems according to the system performance on false positive rate

NCT ID: NCT05088252 Completed - Pituitary Neoplasms Clinical Trials

Desflurane and Anesthesia Recovery Period in Endonasal Endoscopic Pituitary Adenoma Resection

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Nasal packing is required after endoscopic pituitary adenoma resection. The patient can only breathe through the mouth. The blood and secretion in the nasal cavity may be inhaled into the trachea after the operation. GH-secreting pituitary adenoma causes pharyngeal soft tissue and tongue hypertrophy. These conditions increase the risk of respiratory obstruction and hypoxemia during anesthesia recovery. Propofol total intravenous anesthesia has a rapid effect and a low incidence of nausea and vomiting. Patients anesthetized with desflurane recover quickly is conducive to early recovery of respiratory function and orientation. This study intends to compare the effects of desflurane and propofol on the quality of anesthesia recovery period in patients undergoing endonasal endoscopic pituitary adenoma resection and to provide clinical evidence for the use of desflurane in neurosurgical anesthesia.

NCT ID: NCT05080088 Completed - Colorectal Cancer Clinical Trials

Retrospective Evaluation of 3 Colonic Adenoma Detection Strategies

COLODETECT
Start date: April 6, 2021
Phase:
Study type: Observational

Retrospective study, single blind (patient), allowing a posteriori clinical data collection of 90 patients during their passage to the ambulatory endoscopy circuit, to consider 3 groups and thus to deduce a colonic adenoma detection rate for each arm : - Colonoscopy Only Group - Artificial intelligence only group (IA GI GENIUS ™ alone) - Endoscopic Cap and Artificial Intelligence Group (endoscopy cap associated with the GI GENIUS ™ IA System)