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Adenoma clinical trials

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NCT ID: NCT06345105 Recruiting - Clinical trials for Artificial Intelligence

Real Time Effective Withdrawal Time and Adenoma Detection Rate

Start date: April 1, 2024
Phase:
Study type: Observational

The goal of this observational study is to assess the correlation between the artificial intelligence (AI) derived effective withdrawal time (EWT) during colonoscopy and endoscopists' baseline adenoma detection rate (ADR). The association between the AI derived EWT with ADR during the prospective colonoscopy series would also be determined. The colonoscopy video of participants will be monitored by the AI

NCT ID: NCT06342440 Recruiting - Colorectal Cancer Clinical Trials

Early Detection of Advanced Adenomas and Colorectal Cancer

AACRC
Start date: March 15, 2020
Phase:
Study type: Observational

This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.

NCT ID: NCT06326853 Not yet recruiting - Acromegaly Clinical Trials

Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical Models

Start date: March 2024
Phase:
Study type: Observational

The goal of this observational study is to evaluate, retrospectively and prospectively, the effect of different hormonal and neuropeptide dysfunctions on the body composition of patients suffering from hypothalamic-pituitary pathologies, and to evaluate the potential beneficial effect of surgical and medical treatments with agonists and antagonists of hypothalamic neuropeptides, currently available, on the development and treatment of adiposity and negative cross-talk between adiposity and muscle/bone tissue

NCT ID: NCT06322225 Not yet recruiting - Clinical trials for Colorectal Tubular Adenoma

Establishment of Big Data Platform and Biobank for Colorectal Tubular Adenoma Lesions

Start date: May 1, 2024
Phase:
Study type: Observational

Colorectal tubular adenoma is the most common precancerous lesion of colorectal cancer, and the point is that its precise prevention and treatment can reduce the incidence of colorectal cancer.However, the epidemiological characteristics of colorectal tubular adenoma in China are unclear, the rate of missed diagnosis by colonoscopy is high, and the existing diagnosis and treatment techniques are lack of unified quality control standards,which makes it difficult to diagnose and achieve accurate prevention and control. How to improve the precise prevention and treatment of colorectal tubular adenoma and reduce the incidence of colorectal cancer is a major clinical scientific problem that needs to be solved urgently. For this purpose, this study was conducted in colorectal guided by the needs of accurate prevention and treatment of tubular adenoma lesions,and a multi-center colorectal tubular adenoma data management platform and a high-risk population database covering a full range of data including demographic characteristics, lifestyle factors, clinical information, endoscopic data and pathological images were established, biological sample databases of patients with pathological changes and high-risk populations were established, and data quality control and sample quality control standards were formulated standards-based. The pathological prediction model and accurate risk assessment system of colorectal tubular adenoma were constructed by the pathological database.

NCT ID: NCT06307938 Not yet recruiting - Colorectal Cancer Clinical Trials

Circulating Tumor DNA in Patients Summoned for Colonoscopy; - a Liquid Biopsy for Detection, Characterization, Individualized Treatment and Follow-up of Colorectal Cancer

CoLiQ
Start date: January 2025
Phase:
Study type: Observational [Patient Registry]

CoLiQ is an observational study designed to evaluate the clinical usefulness of circulating tumor DNA (ctDNA) markers found in blood, as a liquid biopsy for diagnosis, prognosis and follow-up of colorectal cancer. The main questions it aims to answer are: 1) Can a panel of ctDNA markers identify CRC patients among the other patients summoned for colonoscopy? and 2) Does the type, number and level of ctDNA markers vary with the subtype and clinical course of CRC? Participants will be asked to answer a questionnaire and give a blood sample at inclusion. In addition, patients with CRC will be asked to give an extra test tube at their routine treatment and follow-up blood sampling.

NCT ID: NCT06301048 Completed - Clinical trials for Complication of Treatment

Effectiveness of Endoscopic Papillectomy With Stent for Treating Duodenal Papillary Adenoma

Start date: November 7, 2023
Phase:
Study type: Observational

This is a retrospective study, including 79 patients with duodenal papillary adenoma, who treated with Endoscopic Papillectomy (EP) at Beijing friendship hospital. The cohort included patients who underwent EP with or without Pancreatic Duct (PD) and Common Bile Duct (CBD) stent placement. The investigators assessed the outcomes of EP and the impact of stent placement on complications and recurrence rates.

NCT ID: NCT06297473 Not yet recruiting - Clinical trials for Non-Functional Pituitary Adenoma

Physical Attendance Versus Telephone or Video Follow-up in Patients With Non-functioning Pituitary Tumors.

PITCARE
Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The primary purpose of this study is to compare the safety of routine telephone assessment versus in-person assessment during a two-year period for patients with non-functioning pituitary adenomas. Secondly, to compare the quality of pituitary care in persons having biochemical assessment once versus twice a year. Thirdly, to assess the rationale of repeated assessment of pituitary function and imaging in patients with small pituitary tumors (microadenomas).

NCT ID: NCT06258434 Not yet recruiting - Colorectal Cancer Clinical Trials

Liquid Biopsy Based Multiomics Study for Colorectal Cancer Early Screening

COLO-LIMULOID
Start date: February 10, 2024
Phase:
Study type: Observational [Patient Registry]

The primary objective is to determine the diagnostic sensitivity and specificity of the newly developed liquid biopsy based multiomics Colorectal Cancer (CRC) screening test (CRC-Appareo) for detecting advanced neoplasia (including colorectal cancer and advanced adenomas) in high risk patients and patients with confirmed CRC, using colonoscopy as the reference method. The secondary objective is to compare the screening performance of the multiomics Colorectal Cancer (CRC) screening test with commercially available FIT (Fecal Immunochemical Test) assay in detecting advanced neoplasia.

NCT ID: NCT06251700 Not yet recruiting - Clinical trials for Screening Colonscopy

Longterm Effectiveness of Artificial Intelligence-assisted Colonoscopy on Adenoma Recurrence

ENDOAID-PRO
Start date: April 15, 2024
Phase: N/A
Study type: Interventional

We hypothesize that AI-assisted colonoscopy can reduce post-colonoscopy neoplasia incidence after 3 years, over standard colonoscopy. Moreover, this protective effect may allow surveillance intervals to be lengthened, by modifying long-term outcome of high-risk subgroup.

NCT ID: NCT06250699 Recruiting - Clinical trials for Primary Aldosteronism

A Single Center Randomized Controlled Study on the Promotion of Rapid Recovery

Start date: January 3, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to exploring the role of tubeless after adrenalectomy surgery. The main questions it aims to answer are: 1. The safety of tubeless laparoscopic adrenalectomy; 2. The role of tubeless therapy in rapid recovery after adrenalectomy surgery Participants will be randomly divided into two groups: the non drainage group and the drainage group after laparoscopic adrenal surgery, and their pain, first time out of bed, and intestinal recovery time will be observed.