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Clinical Trial Summary

In the acute posterior circulation strokes, the vertebrobasilar occlusions frequently related to worse outcomes than the anterior ones. However, few studies mentioned the benefit and safety of the emergent stenting in the successful recanalization at these complex occlusions. The investigators investigated whether the improvement of clinical outcome was achieved in postprocedural 3-month.

Clinical Trial Description

Acute ischemic stroke in posterior circulation account for nearly 20 - 25%, in which large vessel occlusions (LVOs) occur 0.8% - 5.7% of two circulation strokes. Although mechanical thrombectomy (MT) has recently been the gold standard in LVOs treatment, the futile recanalization (defined as unfavorable outcome despite early successful recanalization of target artery) rate was showed in posterior circulation higher than in anterior one. Multiple randomized controlled trials (BEST, BASICS, BAOCHE, ATTENTION) have recently reported the benefit of emergent stenting for acute vertebrobasilar occlusions stroke in order to support the successful recanalization in the setting of failure of mechanical thrombectomy. Moreover, the successful recanalization is one of the independent predictors of favorable outcomes. However, the use of the loading dose dual antiplatelet therapy and peri-procedural complications made the safety of emergent stenting remain uncertain. Therefore, the investigators aimed to investigate the impact of emergent stenting on the improved recanalization and clinical outcome in vertebrobasilar occlusions. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT06129721
Study type Interventional
Source Can Tho Stroke International Services Hospital
Contact Cuong Tran Chi, Doctor
Phone +84886559911
Status Recruiting
Phase N/A
Start date December 1, 2020
Completion date June 30, 2024

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