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Acute Stroke clinical trials

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NCT ID: NCT05499442 Recruiting - Acute Stroke Clinical Trials

EEG Motor Movement and Imagery Dataset for Stroke

Start date: January 1, 2022
Phase:
Study type: Observational

The investigators collect and analyze the alpha and beta wave of EEG activity at the motor cortices of the participants, When the motor task is being performed. The Brodmann area 10-20 method and portable EEG equipment was used in the single-center study.

NCT ID: NCT05469438 Recruiting - Acute Stroke Clinical Trials

IMAS Optimization and Applicability in an Acute Stroke Setting.

Start date: October 29, 2021
Phase:
Study type: Observational

The investigator will investigate our Integrated sensor-based Motion Analysis Suite (IMAS) to objectively and quantitatively measure acute stroke patient motor status.

NCT ID: NCT05454397 Recruiting - Acute Stroke Clinical Trials

A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients

Start date: September 1, 2022
Phase:
Study type: Observational

Stroke is the leading cause of premature death and disability, and early recognition and treatment of dysphagia is fundamental to stroke management. Early and full tube feeding in the acute phase of stroke helps to address nutritional problems resulting from dysphagia and impaired consciousness and helps to reduce morbidity and mortality and poor outcomes. Current guidelines for acute stroke management do not address the goal of tube feeding of enteral nutrition for energy and protein. In the treatment of acute stroke, there is a strong global focus on pharmacological thrombolysis or mechanical thrombolysis, with nutritional interventions being a less explored topic. Real-world evidence on large samples, feeding attainment and outcomes, and nutrition in the acute phase of stroke is lacking in China . The aim of this study was to understand the current status of nutritional therapy in stroke hospitalization in neurology and its impact on prognosis nationwide, and to improve the standardized management process of enteral nutrition therapy in the acute phase of stroke.

NCT ID: NCT05351073 Recruiting - Acute Stroke Clinical Trials

The Prehospital Administration of Normobaric Oxygen in Suspected Stroke

NO SUSPENSION
Start date: January 21, 2022
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to explore the feasibility and safety of normobaric oxygen therapy (NBO) under pre-hospital condition in patients with suspected stroke.

NCT ID: NCT05153642 Recruiting - Acute Stroke Clinical Trials

Emergent Microsurgical Intervention in Acute Stroke Patients After Mechanical Thrombectomy Failure Trial

EMIAS
Start date: January 1, 2016
Phase: N/A
Study type: Interventional

With all of the gains that have been achieved with endovascular mechanical thrombectomy revascularization and intravenous thrombolysis logistics, there is still a subgroup of patients with salvageable brain tissue for whom persistent emergent large vessel occlusion (ELVO) portends a catastrophic outcome. Study aims to test the safety and efficacy of emergent microsurgical intervention in acute ischemic stroke patients with symptomatic middle cerebral artery occlusion after failure of mechanical thrombectomy.

NCT ID: NCT05065216 Recruiting - Stroke Clinical Trials

Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)

ReMEDy2
Start date: September 24, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

This is a Phase 2/3 study evaluating the safety and efficacy of DM199 in treating participants presenting within 24 hours of Acute Ischemic Stroke (AIS) onset for whom fibrinolytics and/or a catheter-based procedure, mechanical thrombectomy (MT), are not medically appropriate or available due to constraints of clot location, comorbidity risks, and/or time from estimated onset of stroke. The double-blinded study will be randomized, placebo controlled at up to approximately 100 sites.

NCT ID: NCT04874454 Recruiting - Acute Stroke Clinical Trials

Evaluating Potential Risk of Choking by Laryngeal Ultrasound in Patients With Acute Stroke

Start date: July 14, 2023
Phase: N/A
Study type: Interventional

The investigators evaluate the vocal cord movement in patients with acute stroke by ultrasound. The occurrence of choking or aspiration pneumonia will be collected in one year after the index stroke.

NCT ID: NCT04824911 Recruiting - Acute Stroke Clinical Trials

Statin and Dual Antiplatelet Therapy to Prevent Early Neurological Deterioration in Branch Atheromatous Disease

SATBRAD
Start date: March 23, 2021
Phase: Phase 2
Study type: Interventional

Branch atheromatous disease (BAD) has been reported to contribute to small-vessel occlusion and is associated with a higher possibility of early neurological deterioration (END). Because the pathology of BAD is due to atherosclerosis, the investigators postulate that early intensive medical treatment with dual antiplatelet therapy(DAPT) and high-intensity statin may prevent END and recurrent stroke. The investigators hypothesise that intensive medical therapy can prevent END in BAD using aspirin, clopidogrel and high-intensity statin.

NCT ID: NCT04813445 Recruiting - Ischemic Stroke Clinical Trials

Analysing the Effects of Xingnaojing for Mild-to-severe Acute Ischemic Stroke

Start date: May 28, 2021
Phase: N/A
Study type: Interventional

The main purpose of this trial is to analyse the Effects of Xingnaojing for Mild-to-severe Acute Ischemic Stroke by Metabonomics, proteomics and clinical parameters.

NCT ID: NCT04801225 Recruiting - Acute Stroke Clinical Trials

Early Feasibility Study of the Nervive VitalFlow Stimulation for Acute Ischemic Stroke Patients

Start date: August 24, 2022
Phase: N/A
Study type: Interventional

This Early Feasibility Study (EFS) is a multi-center, open-label single-arm study in 10 acute ischemic stroke (AIS) patients treated with VitalFlow-IS stimulation within 6 hours of symptom onset. The purpose of the EFS is to evaluate initial clinical safety and device functionality in the clinical workflow setting for treatment of acute ischemic stroke patients that will inform design modifications and/or user interface in preparation for next steps consisting of (1) a full safety/feasibility clinical study and (2) randomized controlled pivotal trial with a surrogate endpoint (expedited Premarket Approval (PMA) pathway).