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Effect of PEEP Titration on the EELV Measured by the Nitrogen Dilution Technique in ARDS — TIPEX-VOLTEX  

Acute Respiratory Distress Syndrome Clinical Trial

Official title:
Effect of Positive End Expiratory Pressure Titration on the End-expiratory Lung Volume Measured by the Nitrogen Dilution Technique in Acute Respiratory Distress Syndrome

Clinical Trial Summary

Mechanical ventilation of the patient with acute respiratory distress syndrome is one of the first therapies.

Clinical Trial Description

The application of positive end expiratory pressure is recommended but the question remains "How to set the best positive end-expiratory pressure (PEEP) level for each patient? ". Different titration techniques have been studied on oxygenation and respiratory mechanics parameters without reaching a consensus. Currently we have a module that is connected to the ventilator to collect the patient's lung volume. It will therefore allow us to optimize the settings of the ventilator and to set the best level of positive end-expiratory pressure "best peep" in order to individualize our treatment for each patient. ;

Study Design

Related Conditions & MeSH terms

  • Acute Lung Injury
  • Acute Respiratory Distress Syndrome
  • Respiratory Distress Syndrome, Adult
  • Respiratory Distress Syndrome, Newborn
  • Syndrome
Clinical Trial Details
NCT number NCT04352725
Study type Interventional
Source Centre Hospitalier Intercommunal Aix-Pertuis
Contact Agathe BOULANT
Phone 0442335650
Email aboulant@live.fr
Status Recruiting
Phase N/A
Start date January 20, 2020
Completion date November 30, 2020
View Details
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