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Acute Pain clinical trials

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NCT ID: NCT00470652 Completed - Pain Clinical Trials

Management of Acute Pain in the Emergency Department

Start date: May 2007
Phase: N/A
Study type: Observational

Oligoanalgesia1 has been widely recognized as an issue in emergency department.The purpose of our study is to assess the impact of the implementation of a computer-assisted support program to improve pain management in our ED.

NCT ID: NCT00450099 Completed - Acute Pain Clinical Trials

Minimum Local Anesthetic Volume of Bupivacaine in Labour Epidurals

Start date: October 2005
Phase: N/A
Study type: Interventional

Different medications can be used as analgesics in labor epidurals. Bupivacaine is one of the most commonly used drugs for that purpose. The efficacy of a certain medication injected epidurally depends on the dose that is given. A certain dose can be administered in different concentrations, which will consequently mean different volumes. Our hypothesis is that for each concentration of a certain drug, there has to be a minimum effective volume that will be associated with the best possible performance of the drug. This study is being conducted to find the minimum volume of bupivacaine (a local anesthetic) that produces successful analgesia in 95% of patients in labor.

NCT ID: NCT00446797 Completed - Ankle Sprain Clinical Trials

Open Label Comparative Study On Celecoxib Efficacy And Safety Vs Non-Selective NSAID In Acute Pain Due To Ankle Sprain

Start date: May 2007
Phase: Phase 4
Study type: Interventional

To assess the efficacy of celecoxib loading dose of 400mg followed by 200 mg twice a day (BID) versus oral non-selective NSAIDs in acute pain due to ankle sprain.

NCT ID: NCT00404222 Completed - Pain Clinical Trials

A Study Comparing Vicodin® CR and NORCO® to Placebo in Subjects With Acute Pain Following Bunionectomy

Start date: November 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effectiveness (level of pain control) and safety of the administration of Extended Release Hydrocodone/Acetaminophen and Immediate Release Hydrocodone/Acetaminophen with placebo over a 12 hour dosing period in patients who have had a bunionectomy, and to assess the safety of the drug for 7 days after patients are discharged from the hospital.

NCT ID: NCT00402792 Completed - Pain Clinical Trials

A Study of Extended-Release Hydrocodone/Acetaminophen (Vicodin CR®) in Subjects With Acute Pain Following Bunionectomy

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effectiveness (level of pain control) and safety of the administration of Extended-Release Hydrocodone/Acetaminophen compared to placebo over a 48 hour dosing period in patients who have had bunionectomy surgery and to assess the safety of the drug for 7 days after patients are discharged from the hospital.

NCT ID: NCT00374881 Completed - Acute Pain Clinical Trials

A Study of the Safety and Efficacy of Combination Therapy With Morphine, Phenylephrine and Sorbitol in Human Subjects

Start date: September 2006
Phase: Phase 1/Phase 2
Study type: Interventional

Efficacy and Safety of the combined oral adjuvants phenylephrine and sorbitol on oral low dose morphine analgesia.

NCT ID: NCT00364247 Completed - Hallux Valgus Clinical Trials

A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) in the Treatment of Acute Pain From Bunionectomy Compared With Placebo Followed by a Voluntary Open Label Extension for Safety.

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effectiveness (level of pain control) and safety of the administration of 3 different dose levels of CG5503 compared with oxycodone and with placebo in patients who have had a bunionectomy, and to assess the safety of the drug for 9 days after patients are discharged from the hospital.

NCT ID: NCT00334165 Completed - Acute Pain Clinical Trials

Auricular Acupuncture for Analgesia During Total Hip Arthroplasty

Start date: June 2005
Phase: Phase 2/Phase 3
Study type: Interventional

The aim is to investigate whether auricular acupuncture is superior to sham acupuncture in relief of acute pain and in reduction of analgesics in patients during total hip arthroplasty

NCT ID: NCT00305110 Completed - Acute Pain Clinical Trials

Safety of Hydromorphone in Adult Patients Presenting to the Emergency Department With Acute Severe Pain

Start date: January 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and speed of onset of 2mg intravenous hydromorphone (Dilaudid) in patients weighing at least 150 lbs presenting to the emergency department with acute severe pain

NCT ID: NCT00305058 Completed - Acute Pain Clinical Trials

Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain

Start date: July 2005
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this research study is to determine which opiate pain medication (morphine or hydromorphone (Dilaudid)) is more effective in the treatment of acute pain in patients presenting to the emergency department.