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Acute Pain clinical trials

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NCT ID: NCT05244655 Completed - Postoperative Pain Clinical Trials

Early Postoperative Pain and 30-day Complications Following Major Abdominal Surgery: an Observational Study

Start date: December 1, 2021
Phase:
Study type: Observational [Patient Registry]

In this retrospective cohort study, we assess the relationship between the intensity of early postoperative pain and the risk of infectious- and non-infectious complications within 30 days after major abdominal surgery.

NCT ID: NCT05243940 Recruiting - Analgesia Clinical Trials

Opioid-free Anesthesia in Thyroidectomies

Start date: March 7, 2022
Phase: N/A
Study type: Interventional

The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective thyroidectomies. Recovery parameters and nociception levels throughout the operation will be evaluated

NCT ID: NCT05242328 Recruiting - Post-operative Pain Clinical Trials

Postoperative Analgesia y After Uniportal Video-assisted Thoracoscopic Surgery

Start date: January 5, 2021
Phase: N/A
Study type: Interventional

Ultrasound-guided erector spinae plane block (ESPB) is an interfascial blockade during thoracic anesthesia, first described by Forero in 2016, and is highlighted by technically feasibility and less complication rate. The patient is placed as decubitus position. The anesthesiologists use echo to identify the ipsilateral transverse process at T5 level, and insert the needle to 2-3 cm lateral to the spinous process until contact the transverse process. Then the injected local anesthetic will penetrate via erector spinae muscle to paravertebral space to affect and relieve pain.

NCT ID: NCT05239767 Completed - Acute Pain Clinical Trials

A Randomized Trial of NSAID Dosing Strategies

Start date: June 1, 2022
Phase: Phase 4
Study type: Interventional

This study will compare the efficacy of two different non-steroidal anti-inflammatory drugs (NSAIDs) ketorolac and ibuprofen for people with acute moderate or severe musculoskeletal pain. The investigators will also determine whether taking acetaminophen prior to the NSAID impacts efficacy

NCT ID: NCT05235893 Completed - Analgesia Clinical Trials

Effect of Reflexology on Pain Management in Newborns

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Introduction: Approximately 10-14 painful procedures per day are performed in preterm and term infants during the hospital stay in the first week. The investigators aimed to determine the effect of reflexology being applied to the sole during painful procedures on pain perception, behavioral responses, and physiological changes in newborns compared with other non-pharmacological methods. Material and Method: This study was planned as a randomized controlled trial in term infants being followed up in the Neonatal Intensive Care Unit (NICU) and maternity ward. To reduce pain during attempts to collect venous blood or heel lance which are routinely applied to term newborns before discharge; reflexology on the soles of the foot, 24% sucrose solution, kangaroo care, listening to classical music were applied to the babies and were compared to those who did not have any analgesic method.

NCT ID: NCT05235841 Completed - Blood Pressure Clinical Trials

Effect of Acupressure on Blood Pressure, Heart Rate and Pain Severity

Start date: July 15, 2018
Phase: N/A
Study type: Interventional

Objective: The aim of this study was to evaluate the effect of acupressure applied before CA procedure on systolic and diastolic blood pressure, mean arterial pressure, pulse and pain intensity parameters after CA. Design: The study is a randomized controlled trial. Setting: The study occurred at Cardiology Service (CS) of a Training and Research Hospital in Turkey. Participants: One hundred patients whomet the research criteria.

NCT ID: NCT05233683 Not yet recruiting - Anesthesia Clinical Trials

Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children

Start date: March 2022
Phase: Phase 3
Study type: Interventional

Circumcision is one of the most commonly performed operations in the pediatric population and is a painful procedure. Circumcision is performed with two popular techniques, Plastibell and conventional dissection method (CDM). For intra-operative (OP) and post-OP pain relief, two commonly used local anesthetic techniques are caudal block (CB) and dorsal penile block (DPNB) plus ring block (RB) at the base of the penis. There are very few randomized controlled trials comparing these two methods of intra-OP and post-OP pain relief, for different surgical techniques and there is a lack of well-conducted studies comparing the quality of analgesia, need for rescue analgesia in the early post-OP period, complications, and parental satisfaction comparing these blocks. Furthermore, there is a lot of contradiction in the literature regarding the duration of analgesia produced with these techniques.

NCT ID: NCT05229965 Completed - Clinical trials for Acute Pain Due to Trauma

Paracetamol Vs Caffeine Vs Codeine in the Management of Post Traumatic Pain in Emergencies

Start date: November 1, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to: Compare the effect of paracetamol alone against Paracetamol+Codeine association against the association of paracetamol + Cafeine in the treatment of post-traumatic acute pain of the limbs.

NCT ID: NCT05229055 Recruiting - Acute Pain Clinical Trials

Intranasal Ketamine Versus Subcutaneous Ketamine for Treatment of Post-traumatic Acute Pain in the Emergency Department ( INVESCK )

Start date: April 15, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

Pain is the most common complaint for emergency department (ED) visit. Intranasal ketamine has been shown to provide rapid, well-tolerated, effective analgesia to emergency department (ED) patients with acute pain. few trials have studied ketamine infusion subcutaneously for pain management in trauma patients.

NCT ID: NCT05225766 Completed - Clinical trials for Postoperative Pain, Acute

Comparison of Erector Spinae Plane Block and Rectus Sheath Block

Start date: February 25, 2021
Phase: N/A
Study type: Interventional

In study, The investigators aimed to compare the intraoperative and postoperative analgesic efficacy of erector spinae plane block and rectus sheath block, which investigators routinely perform in surgeries with abdominal lover midline-upper midline incision, morphine consumption with patient-controlled analgesia, as well as patient and surgeon satisfaction.