C-arm Cone Beam CTP Guided Cerebrovascular Interventions

Status Not yet recruiting

Clinical Trial Summary

The study objective for the Phase 2 of this research is to demonstrate and confirm the substantial time savings that can be obtained using cone beam computed tomography (CB-CT) for both complete image acquisition and rapid image reconstruction in a Direct to Angio paradigm (One Stop Shop) for selected acute ischemic stroke (AIS) patients.

Clinical Trial Description

Phase 2 of this research is aimed at validating the feasibility and time savings of bringing selected acute ischemic stroke patients with suspected large vessel occlusion directly on hospital arrival to the angiography suite, avoiding the emergency room and conventional MD-CT imaging. In order to make this phase of the study more robust and to reduce bias on image assessment we will prospectively randomize the patients in a 2:1 fashion to either direct to angio for CB-CT imaging or MD-CT imaging in the emergency room. A total of 60 CB-CT subjects and 30 MD-CT subjects will comprise this cohort. Entrance criteria will be identical to those in Phase 1, except the NIHSS must be greater than 8 which is clinically correlative with a likely large vessel occlusion and, since this is standard of care imaging for acute ischemic stroke, GFR will be removed as an exclusionary criteria. The Phase 1 of this research was registered to NCT03232151. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05536895
Study type	Interventional
Source	University of Wisconsin, Madison
Contact	Gemma Gliori, MS
Phone	608-262-7269
Email	ggliori@uwhealth.org
Status	Not yet recruiting
Phase	N/A
Start date	August 2024
Completion date	April 2025

View Details

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