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Analysis of Telmisartan Administered With Antiretroviral Therapy (ART) in Patients With Acute HIV Infection — SEARCH018  

HIV Infections Clinical Trial

Official title:
Adjunctive Therapy With Telmisartan Instituted With ART During Acute HIV Infection to Reduce the Establishment of Central Nervous System Reservoirs of HIV and Lymph Node Fibrosis [Southeast Asia Research Collaboration With Hawaii (SEARCH) 018]

Clinical Trial Summary

This research project will study whether the drug telmisartan administered in conjunction with antiretroviral therapy (ART) will help reduce nervous system infection with HIV. The investigators are studying the effect of this treatment in people who have contracted HIV infection within the past three weeks, and thus have a form of HIV called acute HIV infection. The investigators will measure biological markers of immune activation in the blood and cerebrospinal fluid to see if telmisartan may reduce the spread of HIV reservoirs in affected patients.

Clinical Trial Description

Note regarding the primary purpose of the study: In the Study Design section, this protocol is classified as "Other", since it is specifically designed to examine the effect of telmisartan administered in conjunction with ART on the size of HIV reservoirs in the central nervous system. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02170246
Study type Interventional
Source Yale University
Contact
Status Completed
Phase Phase 1
Start date January 28, 2015
Completion date June 13, 2018
View Details
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