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Clinical Trial Summary

Investigators evaluate whether differences exsit in acute coronary syndrome(ACS) patients with ejection <45% between participants who take vericiguat regularly and those who donot.


Clinical Trial Description

Vericiguat, a novel soluble guanylate cyclase stimulator, reduced the incidence of cardiovascular death or hospitalization for HF in a population of high-risk patients with heart failure with reduced ejection fraction (HFrEF )who had recently been hospitalized or received intravenous diuretic therapy.Given the increasing incidence of patients with ACS and its challenges posing to life,investigators intend to conduct a prospective observational study. Investigators choose several meaningful endpoints including the time of cardiovascular death or heart failure(HF) hospitalization、inflammatory markers、the value of N-terminal pro-B-type natriuretic peptide(NT-proBNP)、results of echocardiogram and life quality score.By collecting these datas and work on a group of analysis ,investigators evaluate whether differences exsit in ACS patients with ejection <45% between participants who take vericiguat regularly and those who donot. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06321094
Study type Interventional
Source The First Affiliated Hospital with Nanjing Medical University
Contact LianSheng Wang
Phone 13390787111
Email drlswang@njmu.edu.cn
Status Recruiting
Phase Phase 4
Start date October 1, 2023
Completion date December 1, 2025

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