Symptoms of Acute Coronary Syndrome in Medical Regulation

Acute Coronary Syndrome Clinical Trial

— SCAST+  

Official title:

Symptoms of Acute Coronary Syndrome in Medical Regulation: a Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05902130
• Other study ID #: 2023-03Obs-CHRMT
• Status: Completed
• Start date: January 1, 2023
• Est. completion date: October 1, 2023

Study information

• Verified date: December 2023
• Source: Centre Hospitalier Régional Metz-Thionville
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The main objective was to analyze the impact of the gender of the attending physician in the differences in the management of ST+ ACS between men and women.

This study will be conducted in partnership with the interventional cardiology team of the CHR Metz-Thionville and SAMU (emergency call center) of Moselle, which has a detailed registry of coronary angiographies at the center. A retrospective observational study will be carried out over a "typical" period outside of covid at the CHR Metz Mercy (2021-2022) based on coronary angiographies performed in the context of ST+ ACS at the CHR of patients referred by the center 15.

The patient's medical record will be analyzed, going back to his call to the 15 via tape listening. The number of subjects required being calculated at 104 men and 104 women, these patients will be selected from the database of our cardiologist colleagues and we will match one man to one woman by comparing the delays of several items (1st medical contact, time of 1st ECG, medicalization or not, delay of call to the cardiologist, delay of coronary angiography...) according to the sex of the regulator. The consequences of a difference in management will be also evaluated by analyzing in-hospital mortality, mortality at 30 days of management, and functional sequelae at discharge (grades of dyspnea, disturbance of myocardial contractility, LVEF at discharge).

This study based on the differences in questioning according to the gender of the regulating physician would allow better identification of the factors that increase the delay in the management of ST+ ACS in women, and to find avenues of correction in order to limit the loss of opportunity for patients.

The patients included who are still alive will receive a notification of non-objection by mail.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 208
• Est. completion date: October 1, 2023
• Est. primary completion date: October 1, 2023
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• patient with emergency coronary angiography for ST+ ACS

• having made a call to the Emergency Center for the same reason

Exclusion Criteria:

• non-real ST+ ACS

Related Conditions & MeSH terms

• Acute Coronary Syndrome
• Syndrome

Intervention

Other:
• symptoms of a myocardial infarction
Analysis of the differences in symptoms of a myocardial infarction between a man and a woman

Locations

Country	Name	City	State
France	CHR Metz-Thionville/Hopital de Mercy	Metz

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Régional Metz-Thionville

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Delay between the call to the emergency center and the first contact with a physician	Delay (minutes:seconds)	End of the call to the emergency center, less than 10 min
Secondary	Delay between the call to the emergency center and the first electrocardiogram	Delay (hours:minutes)	At hospital discharge, an average of 2 hours
Secondary	Dispatch of a medical ambulance (Y/N)	Number (%)	End of the call to the emergency center, an average of 20 min
Secondary	Delay between the call to the emergency center and the first coronary angiography	Delay (minutes)	At hospital discharge, an average of 2 hours
Secondary	In-hospital mortality	Number (%)	30 days after the call to emergency center
Secondary	Day 30 mortality	Number (%)	30 days after the call to emergency center
Secondary	Left Ventricular Ejection Fraction	Percentage	At hospital discharge, less than 30 days