Acute Renal Insufficiency (ARI) Rate and Predictive Score of ARI in Hospitalized Patients for Acute Coronary Syndrome With ST-segment Elevation Needing Urgent Coronarography

Acute Coronary Syndrome Clinical Trial

— COROAKI  

Official title:

Acute Renal Insufficiency (ARI) Rate and Predictive Score of ARI in Hospitalized Patients for Acute Coronary Syndrome With ST-segment Elevation Needing Urgent Coronarography

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04481126
• Other study ID #: APHP201021
• Status: Recruiting
• Start date: July 1, 2020
• Est. completion date: December 2022

Study information

• Verified date: September 2021
• Source: Assistance Publique - Hôpitaux de Paris
• Contact: Paul GABARRE, MD
• Phone: +33 (0)1 49 09 56 45
• Email: paul.gabarre[@]aphp.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The primary objective of the study aims to evaluate frequence of acute renal insufficiency in patients with ST-segment elevation who need urgent coronary angiography in Ambroise Paré hospital.

The secondary objectives are:

• identify factors of risks associated with the occurrence of acute renal insufficiency after coronarography.

• establish a preprocedure score, predicting of acute renal insufficiency after urgent coronary angiography in patients with ST+ acute coronary syndrome.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 168
• Est. completion date: December 2022
• Est. primary completion date: December 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• patient aged = 18 years;

• evocative symptoms of myocardiac ischemia: typical chest pain; ST-segment elevation and 1 mm in two consecutive peripheral leads and 2 mm in two consecutive precordial derivations, or appearance of a bloc of left branch of novo;

• need urgent coronarography;

• Covered by french social security scheme included CMU.

Exclusion Criteria:

• dialysed patient for chronic renal insufficiency;

• cardio-resporatory arrest;

• cardiogenic choc state;

• prior emergency passage to hospital;

• patient under tutor, gardianship;

• patient covered by french AME scheme;

• pregnant women or breastfeeding;

• all medical, psychological or social situation which should influents the compliance to protocol according to investigator;

• patient refusal.

Related Conditions & MeSH terms

• Acute Coronary Syndrome
• Acute Kidney Injury
• Acute Renal Insufficiency
• Renal Insufficiency
• Syndrome

Locations

Country	Name	City	State
France	Nephrology department, Ambroise Paré hospital, APHP	Boulogne-Billancourt

Sponsors (1)

Lead Sponsor	Collaborator
Assistance Publique - Hôpitaux de Paris

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	incidence of acute renal failure	Acute renal failure is defined as an increase in plasma creatinine of at least 26.5µmol/l within 48 hours, or an increase in plasma creatinine of at least 1.5 times plasma creatinine within 48hours of hospitalisation	at baselin and at 48 hours