Acute Coronary Syndrome Clinical Trial
— AEGIS-IIOfficial title:
A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects With Acute Coronary Syndrome
| Verified date | May 2024 |
| Source | CSL Behring |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
This is a phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of CSL112 on reducing the risk of major adverse CV events [MACE - cardiovascular (CV) death, myocardial infarction (MI), and stroke] in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI), including those managed with percutaneous coronary intervention (PCI) or medically managed.
| Status | Completed |
| Enrollment | 18200 |
| Est. completion date | November 17, 2023 |
| Est. primary completion date | February 16, 2023 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria: - Male or female least 18 years of age - Evidence of myocardial necrosis, consistent with type I (spontaneous) MI - No suspicion of acute kidney injury - Evidence of multivessel coronary artery disease - Presence of established cardiovascular risk factor(s): 1. Diabetes mellitus on pharmacotherapy OR 2. 2 or more of the following: age = 65 years, prior history of MI, peripheral arterial disease Exclusion Criteria: - Ongoing hemodynamic instability - Evidence of hepatobiliary disease - Evidence of severe chronic kidney disease - Plan to undergo scheduled coronary artery bypass graft surgery as treatment for the index MI - Known history of allergies, hypersensitivity, or deficiencies to soy bean, peanut or albumin |
| Country | Name | City | State |
|---|---|---|---|
| Argentina | 0320069 - Hospital Italiano Regional del Sur | Bahía Blanca | |
| Argentina | 0320020 - Clinica Privada | Buenos Aires | |
| Argentina | 0320025 - Fundación Sanatorio Güemes | Ciudad Autonoma Buenos Aires | |
| Argentina | 0320019 - Hospital Británico de Buenos Aires | Ciudad Autónoma Buenos Aires | |
| Argentina | 0320029 - Instituto Cardiovascular de Buenos Aires | Ciudad Autónoma Buenos Aires | |
| Argentina | 0320033 - Corporacion Medica de San Martin | Ciudad Autónoma Buenos Aires | |
| Argentina | 0320034 - Clinica Adventista Belgrano | Ciudad Autónoma Buenos Aires | |
| Argentina | 0320041 - Clinica y Maternidad Suizo Argentina (CyMSA) | Ciudad Autónoma Buenos Aires | |
| Argentina | 0320012 - Sanatorio Allende | Córdoba | |
| Argentina | 0320015 - Clinica Chutro S.R.L. | Córdoba | |
| Argentina | 0320023 - Clínica Privada del Prado | Córdoba | |
| Argentina | 0320026 - Clínica Colombo | Córdoba | |
| Argentina | 0320036 - Hospital Italiano | Córdoba | |
| Argentina | 0320039 - Santatorio Parque S.A. | Córdoba | |
| Argentina | 0320063 - Clinica Romagosa | Córdoba | |
| Argentina | 0320013 - Hospital Municipal de Coronel Suárez | Coronel Suárez | |
| Argentina | 0320040 - Instituto de Cardiología de Corrientes | Corrientes | |
| Argentina | 0320022 - Hospital El Cruce | Florencio Varela | |
| Argentina | 0320014 - Hospital Italiano La Plata | La Plata | |
| Argentina | 0320016 - Sanatorio Modelo Quilmes | Quilmes | |
| Argentina | 0320017 - Entidades Vinculadas al Sanatorio Parque | Rosario | |
| Argentina | 0320044 - Instituto Medico de la Fundacion de Estudios Clínicos | Rosario | |
| Argentina | 0320071 - Hospital Provincial del Centenario | Rosario | |
| Argentina | 0320070 - Hospital Papa Francisco | Salta | |
| Argentina | 0320073 - Instituto Medico De Alta Complejidad - IMAC | Salta | |
| Argentina | 0320027 - Estudios Clínicos de los Arroyos | San Nicolás | |
| Argentina | 0320021 - Sanatorio Medico de Diagnostico y Tratamiento S.A. | Santa Fe | |
| Argentina | 0320032 - Hospital Dr. Jose Maria Cullen | Santa Fe | |
| Argentina | 0320038 - Sanatorio Mayo Privado S.A. | Santa Fe | |
| Argentina | 0320067 - Sanatorio Santa Rosa | Santa Rosa | |
| Argentina | 0320037 - Centro Privado de Cardiologia (CPC) | Tucuman | |
| Argentina | 0320054 - Clínica Privada de Especialidades Médicas de Villa María | Villa María | |
| Australia | 0360057 - Royal Adelaide Hospital | Adelaide | South Australia |
| Australia | 0360032 - Flinders Medical Centre | Bedford Park | South Australia |
| Australia | 0360063 - Cairns Base Hospital | Cairns | Queensland |
| Australia | 0360087 - Campbelltown Hospital | Campbelltown | New South Wales |
| Australia | 0360062 - The Prince Charles Hospital | Chermside | Queensland |
| Australia | 0360092 - Monash Medical Centre | Clayton | Victoria |
| Australia | 0360036 - The Northern Hospital | Epping | Victoria |
| Australia | 0360096 - Peninsula Health | Frankston | Victoria |
| Australia | 0360076 - Geelong Hospital | Geelong | Victoria |
| Australia | 0360061 - Royal Brisbane Hospital | Herston | Queensland |
| Australia | 0360084 - Royal Hobart Hospital | Hobart | Tazmania |
| Australia | 0360081 - Peninsula Heart Centre | Langwarrin | Victoria |
| Australia | 0360069 - Liverpool Hospital | Liverpool | New South Wales |
| Australia | 0360073 - The Alfred Hospital | Melbourne | Victoria |
| Australia | 0360080 - Fiona Stanley Hospital | Murdoch | Western Australia |
| Australia | 0360072 - John Hunter Hospital | New Lambton Heights | |
| Australia | 0360059 - Royal Perth Hospital | Perth | Western Australia |
| Australia | 0360060 - Gold Coast Hospital | Southport | Queensland |
| Australia | 0360070 - Royal North Shore Hospital | St. Leonards | New South Wales |
| Australia | 0360071 - Wollongong Hospital | Wollongong | New South Wales |
| Australia | 0360055 - Queen Elizabeth Hospital | Woodville South | South Australia |
| Austria | 0400035 - Landeskrankenhaus Feldkirch | Feldkirch | |
| Austria | 0400020 - LKH-Universität Hospital Graz | Graz | |
| Austria | 0400028 - Medizinische Universitaet Innsbruck - Universitaetsklinik für Innere Medizin | Innsbruck | |
| Austria | 0400034 - Klinikum Klagenfurt am Wörthersee | Klagenfurt | |
| Austria | 0400031 - Universitatsklinik fuer Innere Medizin II, Kardiol | Salzburg | |
| Belgium | 0560024 - Onze-Lieve-Vrouwziekenhuis VZW (OLV) | Aalst | |
| Belgium | 0560043 - Algemeen Stedelijk Ziekenhuis | Aalst | |
| Belgium | 0560027 - ZNA Middelheim | Antwerpen | |
| Belgium | 0560028 - AZ Klina | Brasschaat | |
| Belgium | 0560020 - AZ Sint-Jan Brugge-Oostende AV | Brugge | |
| Belgium | 0560015 - Clinique Saint Jean | Brussel | |
| Belgium | 0560023 - Centre Hospitalier Universitaire Brugmann | Brussels | |
| Belgium | 0560016 - Ziekenhuis Oost-Limburg | Genk | |
| Belgium | 0560037 - Universitair Ziekenhuis Gent | Gent | |
| Belgium | 0560045 - AZ Sint-Lucas | Gent | |
| Belgium | 0560038 - Jessa Ziekenhuis | Hasselt | |
| Belgium | 0560019 - Centre Hospitalier Régional de Huy | Huy | |
| Belgium | 0560026 - Universitair Ziekenhuis Brussel | Jette | |
| Belgium | 0560046 - AZ Groeninge - Campus Kennedylaan | Kortrijk | |
| Belgium | 0560022 - Centre Hospitalier Universitaire de Tivoli | La Louvière | |
| Belgium | 0560036 - Universitair Ziekenhuis Leuven | Leuven | |
| Belgium | 0560017 - CHR de la Citadelle | Liège | |
| Belgium | 0560053 - AZ Sint-Maarten | Mechelen | |
| Belgium | 0560044 - Heilig Hartziekenhuis Mol | Mol | |
| Belgium | 0560032 - AZ Delta | Roeselare | |
| Belgium | 0560018 - AZ Glorieux | Ronse | |
| Belgium | 0560040 - Campus Saint Elizabeth | Turnhout | |
| Brazil | 0760087 - MK BC Pesquisa Clinica | Balneario Camboriu | |
| Brazil | 0760021 - Fundacao Hospitalar Sao Francisco de Assis | Belo Horizonte | |
| Brazil | 0760056 - Hospital Felício Rocho | Belo Horizonte | |
| Brazil | 0760068 - Gutierrez Cardiologia Clinica e Intervencionista Ltda. | Belo Horizonte | |
| Brazil | 0760085 - Hospital Universitário São José (HUSJ) | Belo Horizonte | |
| Brazil | 0760038 - Instituto de Cardiologia do Distrito Federal (ICDF) | Brasília | |
| Brazil | 0760057 - Centro de Cardiologia Clinica e Pesquisa Dra. Juliana Souza | Brasília | |
| Brazil | 0760059 - Hospital do Coração do Brasil | Brasília | |
| Brazil | 0760060 - Hospital Angelina Caron | Campina Grande Do Sul | |
| Brazil | 0760034 - Hospital e Maternidade Celso Pierro | Campinas | |
| Brazil | 0760035 - Loema - Instituto de Pesquisa Clinica | Campinas | |
| Brazil | 0760077 - Instituto de Pesquisa Clinica de Campinas | Campinas | |
| Brazil | 0760061 - Hospital Universitario Maria Aparecida Pedrossian | Campo Grande | |
| Brazil | 0760036 - Hospital Geral Universitário de Cuiabá - HGU | Cuiabá | |
| Brazil | 0760011 - Hospital Cardiologico Costantini | Curitiba | |
| Brazil | 0760069 - Hospital Universitario Evangelico de Curitiba | Curitiba | Paraná |
| Brazil | 0760037 - Hospital de Messejana Dr. Carlos Alberto Gomes Studart | Fortaleza | |
| Brazil | 0760009 - Santa Casa de Misericordia de Marilia | Marília | |
| Brazil | 0760058 - Hospital São Vicente de Paulo | Passo Fundo | |
| Brazil | 0760040 - Santa Casa de Misericordia de Pelotas | Pelotas | |
| Brazil | 0760012 - Instituto de Cardiologia do Rio Grande do Sul | Porto Alegre | |
| Brazil | 0760015 - Hospital de Clínicas de Porto | Porto Alegre | |
| Brazil | 0760019 - Hospital São Lucas da PUCRS | Porto Alegre | |
| Brazil | 0760052 - Hospital Nossa Senhora da Conceicao (HNSC) | Porto Alegre | |
| Brazil | 0760018 - Pronto Socorro Cardiológico de Pernambuco (PROCAPE) | Recife | |
| Brazil | 0760062 - Hospital Agamenon Magalhães | Recife | |
| Brazil | 0760075 - Instituto D'Or de Pesquisa e Ensino | Rio De Janeiro | |
| Brazil | 0760025 - Hospital Santa Izabel | Salvador | |
| Brazil | 0760044 - Hospital da Bahia | Salvador | |
| Brazil | 0760053 - Fundação Bahiana de Cardiologia | Salvador | |
| Brazil | 0760055 - Instituto Cardio Pulmonar da Bahia - Hospital | Salvador | |
| Brazil | 0760041 - Hospital e Maternidade Dr. Christovao da Gama | Santo André | |
| Brazil | 0760027 - CEMEC - Centro Multidisciplinar de Estudos Clínicos | São Bernardo Do Campo | |
| Brazil | 0760047 - Instituto de Cardiologia de Santa Catarina (ICSC) | São José | |
| Brazil | 0760016 - Faculdade de Medicina de Sao Jose do Rio Preto-SP - Hospital | São José Do Rio Preto | |
| Brazil | 0760031 - Instituto do Coração (InCor) | São Paulo | |
| Brazil | 0760083 - Irmandade da Santa Casa de Misericordia de Sao Paulo | São Paulo | |
| Brazil | 0760010 - Eurolatino Medical Research | Uberlândia | |
| Brazil | 0760039 - Hospital Evangelico de Vila Velha (HEVV) | Vila Velha | |
| Brazil | 0760081 - Hospital Universitário Cassiano Antonio Moraes (HUCAM) | Vitória | |
| Brazil | 0760028 - Santa Casa de Votuporanga | Votuporanga | |
| Bulgaria | 1000023 - MHAT "Pulse AD" | Blagoevgrad | |
| Bulgaria | 1000043 - Multiprofile Hospital for Active Treatment Blagoevgrad AD | Blagoevgrad | |
| Bulgaria | 1000074 - "UMHAT Deva Mariya" EOOD | Burgas | |
| Bulgaria | 1000072 - Multiprofile Hospital for Active Treatment - Dobrich AD | Dobrich | |
| Bulgaria | 1000029 - Multiprofile Hospital for Active Treatment AD Haskovo | Haskovo | |
| Bulgaria | 1000045 - MHAT City Clinic - Sv. Georgi EOOD | Lom | |
| Bulgaria | 1000036 - MHAT-Higia | Pazardzhik | |
| Bulgaria | 1000053 - Multiprofile Hospital For Active Treatment - Pazardzhik AD | Pazardzhik | |
| Bulgaria | 1000049 - SHATC Sv. Georgi - Pernik | Pernik | |
| Bulgaria | 1000057 - Specialized Hospital for Active Treatment in Cardiology EAD | Pleven | |
| Bulgaria | 1000071 - University Multiprofile Hospital for Active Treatment "Dr. G" | Pleven | |
| Bulgaria | 1000058 - Multiprofile Hospital for Active Treatment Plovdiv AD | Plovdiv | |
| Bulgaria | 1000033 - University Multiprofile Hospital for Active Treatment | Sofia | |
| Bulgaria | 1000035 - "MHAT "Sveta Anna"" - Sofia AD | Sofia | |
| Bulgaria | 1000038 - Acibadem City Clinic University Hospital, EOOD | Sofia | |
| Bulgaria | 1000044 - Second Multiprofile Hospital for Active Treatment - Sofia EA | Sofia | |
| Bulgaria | 1000047 - University Hospital for Active Treatment & Emergency Medicine | Sofia | |
| Bulgaria | 1000054 - Multiprofile Hospital for Active Treatment "National Cardiac Hospital" | Sofia | |
| Bulgaria | 1000070 - University Multiprofile Hospital for Active Treatment Alexa | Sofia | |
| Bulgaria | 1000028 - SHAT Cardiology Varna - EAD | Varna | |
| Bulgaria | 1000024 - Multiprofile District Hospital | Veliko Tarnovo | |
| Canada | 1240096 - William Osler Health System | Brampton | Ontario |
| Canada | 1240063 - Heritage Medical Research Clinic | Calgary | Alberta |
| Canada | 1240032 - Royal Alexandra Hospital | Edmonton | Alberta |
| Canada | 1240058 - University of Alberta Hospital | Edmonton | Alberta |
| Canada | 1240065 - Hamilton Health Sciences | Hamilton | Ontario |
| Canada | 1240102 - Royal Inland Hospital | Kamloops | British Columbia |
| Canada | 1240101 - Kelowna General Hospital | Kelowna | British Columbia |
| Canada | 1240091 - Kingston General Hospital | Kingston | Ontario |
| Canada | 1240107 - Clinique de Cardiologie de Levis | Levis | Quebec |
| Canada | 1240088 - Montreal Heart Institute | Montreal | Quebec |
| Canada | 1240092 - CHUM - Centre Hospitalier de l'Universite de Montreal | Montreal | Quebec |
| Canada | 1240106 - McGill University Health Centre (MUHC) | Montreal | Quebec |
| Canada | 1240068 - Fraser Clinical Trials, Inc. | New Westminster | British Columbia |
| Canada | 1240069 - York PCI Group, Inc. | Newmarket | Ontario |
| Canada | 1240093 - Halton Healthcare - Oakville Trafalgar Memorial Hospital | Oakville | Ontario |
| Canada | 1240077 - Ottawa Heart Institute | Ottawa | Ontario |
| Canada | 1240078 - Kawartha Cardiology Clinical Trials | Peterborough | Ontario |
| Canada | 1240071 - Institut universitaire de cardiologie et de pneumologie de Quebec | Quebec | |
| Canada | 1240083 - CHU de Quebec-Universite-Laval, HDQ | Québec | Quebec |
| Canada | 1240090 - New Brunswick Heart Centre Research Initiative | Saint John | New Brunswick |
| Canada | 1240099 - Centre Hospital Saint Georges de Beauce | Saint-Georges | Quebec |
| Canada | 1240095 - Royal University Hospital | Saskatoon | Saskatchewan |
| Canada | 1240087 - CIUSSS de l'Estrie-CHUS | Sherbrooke | Quebec |
| Canada | 1240113 - Niagara Health System, St. Catherines Site | St. Catharines | Ontario |
| Canada | 1240081 - Saint Jerome Medical Research, Inc. | St. Jerome | Quebec |
| Canada | 1240060 - Health Sciences Centre | St. John's | Newfoundland and Labrador |
| Canada | 1240061 - SMH Cardiology Clinical Trials Inc. | Surrey | British Columbia |
| Canada | 1240059 - Centre Hospitalier Pierre-Le Gardeur | Terrebonne | Quebec |
| Canada | 1240079 - Toronto General Hospital | Toronto | |
| Canada | 1240097 - St. Michael's Hospital | Toronto | Ontario |
| Canada | 1240066 - Centre Integre Universitaire de la Mauricie-et-du-Centre-du-Quebec | Trois-Rivières | Quebec |
| Canada | 1240074 - Vancouver General Hospital | Vancouver | British Colombia |
| Canada | 1240062 - Saint Boniface General Hospital | Winnipeg | Manitoba |
| Chile | 1520014 - Hospital Clinico Regional Dr. Guillermo Grant Benavente | Concepcion | |
| Chile | 1520017 - Hospital San Juan de Dios | Santiago | |
| Chile | 1520026 - Hospital Las Higueras | Talcahuano | |
| Chile | 1520004 - Hospital Dr. Hernan Henriquez Aravena | Temuco | |
| Chile | 1520013 - Hospital de Victoria | Victoria | |
| Colombia | 1700007 - Fundacion Cardiomet Eje Cafetero CEQUIN | Armenia | |
| Colombia | 1700008 - Clinica de la Costa | Barranquilla | |
| Colombia | 1700006 - Hospital Universitario San Ignacio | Bogotá | |
| Colombia | 1700010 - Centro Medico Imbanaco | Cali | |
| Colombia | 1700011 - Fundación Valle del Lili | Cali | |
| Colombia | 1700012 - Fundación Oftalmológica de Santander - Clinica FOSCAL | Floridablanca | |
| Colombia | 1700017 - Fundación Cardiovascular de Colombia | Floridablanca | |
| Colombia | 1700018 - Caja de Compensacion Familiar de Caldas | Manizales | |
| Colombia | 1700013 - Rodrigo Botero SAS | Medellín | |
| Colombia | 1700015 - Hospital Pablo Tobon Uribe | Medellín | |
| Colombia | 1700024 - Fundación Hospitalaria San Vicente de Paul | Medellín | |
| Croatia | 1910010 - Županijska Bolnica Cakovec | Cakovec | |
| Croatia | 1910008 - Specijalna Bolnica za Medicinsku Rehabilitaciju Krapinske Toplice | Krapinske Toplice | |
| Croatia | 1910019 - Klinicki Bolnicki Centar Rijeka - Susak | Rijeka | |
| Croatia | 1910003 - Klinicki Bolnicki Centar Zagreb | Zagreb | |
| Croatia | 1910012 - Klinicka Bolnica Sveti Duh | Zagreb | |
| Croatia | 1910013 - Klinicki bolnicki centar Sestre milosrdnice | Zagreb | |
| Czechia | 2030048 - Fakultní Nemocnice Brno | Brno | |
| Czechia | 2030057 - Fakultní Nemocnice Hradec Králové | Hradec Králové | |
| Czechia | 2030031 - Nemocnice Jablonec nad Nisou, p.o. | Jablonec Nad Nisou | |
| Czechia | 2030073 - Karlovarska Krajska Nemocnice a.s. | Karlovy Vary | |
| Czechia | 2030040 - Oblastní Nemocnice Kladno, a.s. | Kladno | |
| Czechia | 2030061 - Oblastní nemocnice Náchod, a.s | Náchod | |
| Czechia | 2030041 - Nemocnice Pardubickeho kraje, a.s. - Pardubicka nemocnice | Pardubice | |
| Czechia | 2030020 - Fakultní nemocnice Královské Vinohrady | Praha | |
| Czechia | 2030038 - Vseobecna Fakultni Nemocnice, Ustav hematologie a krevni transfuze | Praha | |
| Czechia | 2030052 - Všeobecná fakultní nemocnice v Praze | Praha | |
| Czechia | 2030071 - Ústrední vojenská nemocnice - Vojenská fakultní nemocnice Praha | Praha | |
| Czechia | 2030050 - Nemocnice Slaný | Slaný | |
| Czechia | 2030059 - Uherskohradištská nemocnice a.s. | Uherské Hradište | |
| Denmark | 2080012 - Aalborg Universitetshospital | Aalborg | |
| Denmark | 2080009 - Sydvestjysk Sygehus - Esbjerg | Esbjerg | |
| Denmark | 2080021 - Amager and Hvidovre Hospital - Medical Department | Glostrup | |
| Denmark | 2080011 - Gentofte Hospital | Hellerup | |
| Denmark | 2080016 - Medicinsk Afdeling - Herning Sygehus | Herning | |
| Denmark | 2080008 - Hvidovre Hospital | Hvidovre | |
| Denmark | 2080022 - Amager Sygehus - Kardiologisk Klinik | København | |
| Denmark | 2080015 - Koege Sygehus - University Hospital Sjaelland | Køge | |
| Denmark | 2080019 - Sjaellands Universitetshospital - Kardiologisk Afdeling | Roskilde | |
| Denmark | 2080018 - Regionshospitalet Silkeborg | Silkeborg | |
| Denmark | 2080014 - Svendborg Sygehus, Ward "Forskningsenheden Afd M Svendborg" | Svendborg | |
| Denmark | 2080020 - Hjertesygdomme | Regionshospitalerne i Viborg og Skive | Viborg | |
| Estonia | 2330005 - North Estonia Medical Centre Foundation | Tallinn | |
| Estonia | 2330006 - East-Tallinn Central Hospital | Tallinn | |
| Estonia | 2330004 - Tartu University Hospital | Tartu | |
| Finland | 2460006 - Helsinki University Central Hospital (HUCH) | Helsinki | |
| Finland | 2460011 - Turku University Hospital (TYKS) | Turku | |
| France | 2500081 - CHU Besançon - Hôpital Jean Minjoz | Besançon | |
| France | 2500163 - CHU Caen | Caen | |
| France | 2500162 - CHRU de Tours - Hopital Trousseau | Chambray Les Tours | |
| France | 2500107 - Centre Hospitalier Sud Francilien | Corbeil-Essonnes | |
| France | 2500103 - CHU de Grenoble | Grenoble | |
| France | 2500078 - Centre Hospitalier Louis Pasteur | Le Coudray | |
| France | 2500117 - Centre Chirurgical Marie Lannelongue | Le Plessis-Robinson | |
| France | 2500112 - Centre Hospitalier Régional Universitaire de Lille (CHRU) | Lille CEDEX | |
| France | 2500082 - Clinique du Pont de Chaume | Montauban | |
| France | 2500091 - CHRU Montpellier - Arnaud de Villeneuve | Montpellier | |
| France | 2500110 - CHU de Nantes | Nantes | |
| France | 2500079 - CHU de Nice - Hôpital Pasteur | Nice | |
| France | 2500105 - CHU de Nimes - Hopital Universitaire Caremeau | Nimes | |
| France | 2500046 - Hopital Pitie-Salpetriere | Paris | |
| France | 2500090 - Hôpital Lariboisière | Paris | |
| France | 2500101 - Hopital Paris Saint Joseph | Paris | |
| France | 2500042 - CHU Hopitaux de Bordeaux - Hôpital Haut-Lévêque | Pessac | |
| France | 2500165 - CHU de Poitiers | Poitiers | |
| France | 2500120 - Centre Hospitalier Annecy Genevois | Pringy | |
| France | 2500092 - Centre Hospitalier Régional Metz-Thionville | Thionville | |
| France | 2500080 - CHU de Toulouse - Hopital Rangueil - Cardiologie | Toulouse | |
| Georgia | 2680002 - Helsicore - Israeli Georgian Medical Research Clinic | Tbilisi | |
| Georgia | 2680004 - Clinical Cardology Institute Ltd. | Tbilisi | |
| Georgia | 2680010 - MediClub Georgia | Tbilisi | |
| Georgia | 2680012 - Chapidze Emergency Cardiology Center | Tbilisi | |
| Georgia | 2680013 - Tbilisi Heart and Vascular Clinic LTD | Tbilisi | |
| Georgia | 2680015 - Chapidze Emergency Cardiology Center | Tbilisi | |
| Georgia | 2680018 - TSMU - Alexandre Aladashvili University Clinic | Tbilisi | |
| Georgia | 2680020 - Cardiological Clinic "Guli" | Tbilisi | |
| Georgia | 2680023 - LTD "Samgori Medi" | Tbilisi | |
| Georgia | 2680026 - Georgian-Dutch Hospital MEDISON | Tbilisi | |
| Georgia | 2680027 - Tbilisi State Medical University (TSMU) - S. Khechinashvili | Tbilisi | |
| Germany | 2760133 - SLK - Klinikum am Plattenwald | Bad Friedrichshall | |
| Germany | 2760143 - Vivantes Klinikum Am Urban | Berlin | |
| Germany | 2760170 - Charite - UB - CVK - Medizinische Klinik | Berlin | |
| Germany | 2760184 - Praxis Dr. Med. Nicole Toursarkissian | Berlin | |
| Germany | 2760146 - Innere Medizin I, Marienhaus Klinikum Eifel Bitburg | Bitburg | |
| Germany | 2760155 - Universitätsklinikum Bonn | Bonn | |
| Germany | 2760141 - Klinikum Coburg GmbH | Coburg | |
| Germany | 2760139 - Staedtisches Klinikum Dresden-Friedrichstadt - I. Medizinisc | Dresden | |
| Germany | 2760243 - HELIOS Klinikum Erfurt | Erfurt | |
| Germany | 2760164 - Elisabeth-Krankenhaus Essen GmbH Klinik für Kardiologie und Angiologie | Essen | |
| Germany | 2760168 - Klinikum Frankfurt Höchst GmbH | Frankfurt am Main | |
| Germany | 2760193 - CardioVaskulares Centrum Frankfurt | Frankfurt Am Main | |
| Germany | 2760119 - Universitätsklinikum Freiburg | Freiburg im Breisgau | |
| Germany | 2760219 - Universitätsklinikum Freiburg | Freiburg im Breisgau | |
| Germany | 2760140 - Cardiologicum Hamburg - Studienzentrum | Hamburg | |
| Germany | 2760149 - Asklepios Klinik Altona | Hamburg | |
| Germany | 2760188 - Asklepios Klinik Barmbek | Hamburg | |
| Germany | 2760190 - Asklepios Kliniken Hamburg GmbH | Hamburg | |
| Germany | 2760135 - University Hospital Jena | Jena | |
| Germany | 2760132 - Ambulantes Herzzentrum Kassel | Kassel | |
| Germany | 2760181 - Asklepios Klinik Langen | Langen | |
| Germany | 2760111 - Klinikum der Stadt Ludwigshafen gGmbH | Ludwigshafen | |
| Germany | 2760130 - Universitätsmedizin der Johannes Gutenberg-Universität Mainz | Mainz | |
| Germany | 2760186 - Katholisches Klinikum Mainz - Klinik fuer Innere Medizin I | Mainz | |
| Germany | 7240030 - Universitätsmedizin der Johannes Gutenberg-Universität Mainz | Mainz | |
| Germany | 2760147 - GPR Klinikum Rüsselsheim II - Medizinische Klinik Innere Medizin | Rüsselsheim am Main | |
| Germany | 2760176 - Evangelisches Krankenhaus Witten | Witten | |
| Greece | 3000022 - University of Athens - Hippokration General Hospital | Athens | |
| Greece | 3000023 - National and Kapodistrian University of Athens (NKUA) - Scho | Athens | |
| Greece | 3000027 - GENERAL HOSPITAL Korgialenio - Benakio HRC | Athens | |
| Greece | 3000026 - University General Hospital Attikon | Chaidari | |
| Greece | 3000016 - General Hospital of Thessaloniki "G. Papanikolaou" | Chortiátis | |
| Greece | 3000008 - University of Ioannina School of Medicine - Michaelidion Cardiac Center | Ioannina | |
| Greece | 3000010 - University Hospital of Ioannina | Ioannina | |
| Greece | 3000029 - University of Thessaly- General University Hospital of Laris | Larissa | |
| Greece | 3000025 - University General Hospital of Patras | Patra | |
| Greece | 3000007 - General Hospital of Nikea "Agios Panteleimon" | Piraeus | |
| Greece | 3000013 - University General Hospital of Thessaloniki AHEPA | Thessaloniki | |
| Hong Kong | 3440004 - Queen Elizabeth Hospital (QEH) | Kowloon | |
| Hong Kong | 3440005 - Princess Margaret Hospital | Kwai Chung | |
| Hong Kong | 3440006 - Prince of Wales Hospital | Sha Tin | |
| Hungary | 3480016 - Budai Irgalmasrendi Kórház | Budapest | |
| Hungary | 3480024 - Bajcsy-Zsilinszky Hospital | Budapest | |
| Hungary | 3480028 - Magyar Honvédség Egészségügyi Központ | Budapest | |
| Hungary | 3480033 - Semmelweis University, Faculty of Medicine | Budapest | |
| Hungary | 3480040 - Jahn Ferenc Dél-pesti Kórház és Rendelointézet | Budapest | |
| Hungary | 3480019 - Debreceni Egyetem Klinikai Központ | Debrecen | |
| Hungary | 3480025 - Dombovari Szent Lukacs Egeszsegugyi Kft | Dombóvár | |
| Hungary | 3480023 - Petz Aladar County Teaching Hospital | Gyor | |
| Hungary | 3480029 - Békés Megyei Pándy Kálmán Kórház | Gyula | |
| Hungary | 3480045 - Somogy Megyei Kaposi Mór Oktató Kórház | Kaposvár | |
| Hungary | 3480036 - Bács-Kiskun Megyei Kórház | Kecskemét | |
| Hungary | 3480015 - Jósa András Oktatókórház | Nyíregyháza | |
| Hungary | 3480022 - University of Szeged - Second Department of Medicine & Cardiology Centre | Szeged | |
| Hungary | 3480020 - Fejér Megyei Szent György Egyetemi Oktató Kórház | Székesfehérvár | |
| Hungary | 3480035 - Tolna Megyei Balassa Janos Korhaz | Szekszárd | |
| Hungary | 3480018 - Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház-Rendelointéz | Szolnok | |
| Hungary | 3480026 - Zala Megyei Szent Rafael Kórház | Zalaegerszeg | |
| Israel | 3760021 - Emek Medical Center | Afula | |
| Israel | 3760041 - Emek Medical Center | Afula | |
| Israel | 3760028 - Barzilai Medical Center | Ashkelon | |
| Israel | 3760034 - Assaf Harofeh Medical Center - Cardiology Division | Be'er Ya'aqov | |
| Israel | 3760024 - Soroka Medical Center | Beer Sheva | |
| Israel | 3760032 - Hillel Yaffe Medical Center | Hadera | |
| Israel | 3760014 - Rambam Medical Center | Haifa | |
| Israel | 3760022 - Bnai Zion Medical Center | Haifa | |
| Israel | 3760012 - Hadassah Ein Karem Hospital | Jerusalem | |
| Israel | 3760023 - Shaare Zedek Medical Center | Jerusalem | |
| Israel | 3760029 - Hadassah Medical Center-Mount Scopus | Jerusalem | |
| Israel | 3760037 - Tel Aviv University Sackler School of Medicine - Meir Medica | Kfar Saba | |
| Israel | 3760020 - Galilee Medical Center | Nahariya | |
| Israel | 3760026 - The Baruch Padeh Medical Center | Nazareth | |
| Israel | 3760035 - The Baruch Padeh Medical Center | Nazareth | |
| Israel | 3760025 - Rabin Medical Center - Hasharon Hospital | Petah Tiqva | |
| Israel | 3760018 - Leviev Heart Center, Chaim Sheba Medical Center | Ramat Gan | |
| Israel | 3760027 - Kaplan Medical Center | Rehovot | |
| Israel | 3760019 - Ziv MC | Safed | |
| Israel | 3760036 - Assuta Medical Center | Tel Aviv-Yafo | |
| Israel | 3760038 - Tel Aviv Sourasky Medical Center | Tel Aviv-Yafo | |
| Italy | 3800062 - ASST Papa Giovanni XXIII | Bergamo | |
| Italy | 3800075 - ASST degli Spedali Civili di Brescia | Brescia | |
| Italy | 3800170 - Fondazione Poliambulanza Istituto Ospedaliero | Brescia | |
| Italy | 3800085 - Azienda Socio-Sanitaria Territoriale della Valle Olona | Busto Arsizio | |
| Italy | 3800079 - Azienda Ospedaliera di Caserta "Sant'Anna e San Sebastiano" | Caserta | |
| Italy | 3800107 - Università degli Studi "Magna Graecia" di Catanzaro | Catanzaro | |
| Italy | 3800129 - Azienda Ospedaliero-Universitaria Careggi | Firenze | |
| Italy | 3800088 - Centro Cardiologico Monzino | Milano | |
| Italy | 3800141 - IRCCS MultiMedica | Milano | |
| Italy | 3800087 - Azienda Ospedaliera Universitaria "Federico II" | Napoli | |
| Italy | 3800123 - AORN - Ospedali dei Colli Ospedale V. Monaldi | Napoli | |
| Italy | 3800090 - Gruppo Ospedaliero San Donato - Policlinico San Marco | Osio Sotto | |
| Italy | 3800082 - Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone | Palermo | |
| Italy | 3800110 - Fondazione IRCCS Policlinico San Matteo | Pavia | |
| Italy | 3800080 - ASL Roma 2 | Roma | |
| Italy | 3800106 - Università degli Studi di Roma "La Sapienza" | Roma | |
| Italy | 3800056 - Istituto Clinico Humanitas | Rozzano | |
| Japan | 3920130 - Eiyukai Ayase Heart Hospital | Adachi-Ku | |
| Japan | 3920106 - Hyogo Prefectural Amagasaki General Medical Center | Amagasaki-Shi | |
| Japan | 3920095 - Showa University Fujigaoka Hospital | Aoba-Ku | |
| Japan | 3920156 - Asahi General Hospital | Asahi-Shi | |
| Japan | 3920122 - Sakakibara Heart Institute | Fuchu-Shi | |
| Japan | 3920105 - Fukuoka University Hospital | Fukuoka-Shi | |
| Japan | 3920101 - Teikyo University Hospital | Itabashi-Ku | |
| Japan | 3920116 - Nihon University Itabashi Hospital | Itabashi-Ku | |
| Japan | 3920094 - Juntendo University Shizuoka Hospital | Izunokuni-Shi | |
| Japan | 3920111 - Ishikawa Prefectural Central Hospital | Kanazawa-Shi | |
| Japan | 3920108 - Fukuoka Tokushukai Hospital | Kasuga-Shi | |
| Japan | 3920134 - Kimitsu Chuo Hospital | Kisarazu-Shi | |
| Japan | 3920092 - Chikamori Hospital | Kochi-Shi | |
| Japan | 3920100 - Saiseikai Kumamoto Hospital | Kumamoto-Shi | |
| Japan | 3920109 - National Hospital Organization Kumamoto Medical Center | Kumamoto-Shi | |
| Japan | 3920113 - Kumamoto University Hospital | Kumamoto-Shi | |
| Japan | 3920154 - Kurashiki Central Hospital | Kurashiki-shi | Okayama |
| Japan | 3920110 - Kurume University Hospital | Kurume-Shi | |
| Japan | 3920136 - Shin Koga Hospital | Kurume-Shi | |
| Japan | 3920103 - Kusatsu General Hospital | Kusatsu-Shi | |
| Japan | 3920115 - Matsusaka Chuo General Hospital | Matsusaka-Shi | |
| Japan | 3920119 - Ehime Prefectural Central Hospital | Matsuyama-Shi | |
| Japan | 3920114 - Toho University Ohashi Medical Center | Meguro-ku | |
| Japan | 3920093 - Miyazaki Medical Association Hospital | Miyazaki-Shi | |
| Japan | 3920107 - Teine Keijinkai Hospital | Sapporo-Shi | |
| Japan | 3920118 - Sapporo Medical University Hospital | Sapporo-Shi | |
| Japan | 3920121 - Hokkaido Cardiovascular Hospital | Sapporo-Shi | |
| Japan | 3920117 - Sendai Open Hospital | Sendai-Shi | |
| Japan | 3920149 - Tohoku University Hospital | Sendai-Shi | |
| Japan | 3920132 - Tosei General Hospital | Seto-Shi | |
| Japan | 3920123 - Tokyo Women's Medical University Hospital | Shinjuku-Ku | |
| Japan | 3920104 - Shizuoka City Shizuoka Hospital | Shizuoka-Shi | |
| Japan | 3920120 - National Cerebral and Cardiovascular Center | Suita-Shi | |
| Japan | 3920126 - Kagawa Prefectural Hospital | Takamatsu-Shi | |
| Japan | 3920102 - Oji General Hospital | Tomakomai-Shi | |
| Japan | 3920128 - Tokyo Bay Urayasu Ichikawa Medical Center | Urayasu-Shi | |
| Japan | 3920099 - Yokohama City University Medical Center | Yokohama-Shi | |
| Japan | 3920133 - Kanagawa Cardiovascular and Respiratory Center | Yokohama-Shi | |
| Korea, Republic of | 4100021 - Chungbuk National University Hospital | Cheongju | |
| Korea, Republic of | 4100016 - Veterans Health Service Medical Center | Gangdong | |
| Korea, Republic of | 4100013 - Kyung Hee University Medical Center | Hoegi-dong | Dongdaemun-gu |
| Korea, Republic of | 4100017 - Chungnam National University Hospital | Junggu | |
| Korea, Republic of | 4100024 - Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do |
| Korea, Republic of | 4100008 - Seoul National University Hospital | Seoul | |
| Korea, Republic of | 4100018 - Asan Medical Center | Seoul | |
| Korea, Republic of | 4100019 - Kangbuk Samsung Hospital | Seoul | Jongro-gu |
| Korea, Republic of | 4100020 - Kyung Hee University Hospital at Gangdong | Seoul | Gangdong-gu |
| Korea, Republic of | 4100025 - Korea University Anam Hospital | Seoul | Seongbuk-gu |
| Korea, Republic of | 4100010 - The Catholic University of Korea, St. Vincent's Hospital | Suwon | |
| Korea, Republic of | 4100014 - Yonsei University, Wonju Severance Christian Hospital | Wonju | Gangwon-do |
| Korea, Republic of | 4100015 - Pusan National University Yangsan Hospital | Yangsan | Gyeongsangnam-do |
| Korea, Republic of | 4100022 - Hallym University Sacred Heart Hospital | Yeongdeungpo-dong | |
| Latvia | 4280004 - Daugavpils Regional Hospital | Daugavpils | |
| Latvia | 4280007 - Liepajas Regionala Slimnica | Liepaja | |
| Latvia | 4280005 - SIA Rigas Austrumu Kliniska Universitates Slimnica - Gaileze | Riga | |
| Latvia | 4280008 - Pauls Stradins Clinical University Hospital | Riga | |
| Latvia | 4280003 - Vidzemes slimnica | Valmiera | |
| Lithuania | 4400008 - Republican Šiauliai Hospital | Šiauliai | |
| Lithuania | 4400004 - Hospital of Lithuanian University of Health Sciences - Kauno Klinikos | Kaunas | |
| Lithuania | 4400007 - Klaipeda Seamen's Hospital | Klaipeda | |
| Lithuania | 4400006 - Public Institution Republican Panevezys Hospital | Panevežys | |
| Lithuania | 4400005 - Vilnius University Hospital Santaros Klinikos | Vilnius | |
| Malaysia | 4580015 - Hospital Universiti Sains Malaysia | Kota Bharu | |
| Malaysia | 4580004 - Queen Elizabeth Hospital II | Kota Kinabalu | Sabah |
| Malaysia | 4580007 - Institut Jantung Negara | Kuala Lumpur | |
| Malaysia | 4580008 - Universiti Kebangsaan Malaysia Medical Centre | Kuala Lumpur | |
| Malaysia | 4580016 - University Malaya Medical Centre | Kuala Lumpur | |
| Malaysia | 4580003 - Hospital Tengku Ampuan Afzan | Kuantan | |
| Malaysia | 4580002 - Hospital Umum Sarawak (HUS) - The Cardiac Centre | Kuching | |
| Malaysia | 4580019 - Hospital Pulau Pinang | Pulau Pinang | |
| Malaysia | 4580005 - Universiti Teknologi MARA (UiTM) | Sungai Buloh | |
| Mexico | 4840004 - Hospital Cardiológica Aguascal | Aguascalientes | |
| Mexico | 4840014 - Investigacion Biomedica para el Desarrollo de Farmacos S.A d | Aguascalientes | |
| Mexico | 4840046 - Unidad de Investigacion | Chihuahua | |
| Mexico | 4840077 - Unidad de Investigacion en Salud (UIS) | Chihuahua | |
| Mexico | 4840006 - Centro para el Desarrollo de la Medicina y de Asistencia Méd | Culiacán | |
| Mexico | 4840008 - Hospital Civil de Guadalajara - Nuevo Hospital Civil de Guadalajara | Guadalajara | Jalisco |
| Mexico | 4840033 - Virgen Cardiovascular Research S.C. | Guadalajara | |
| Mexico | 4840020 - Centro de Estudios de Alta Especialidad de Sinaloa, S.C. | Mazatlán | |
| Mexico | 4840016 - Instituto Nacional de Cardiologia Ignacio Chavez | Mexico | |
| Mexico | 4840034 - Hospital de Jesus | Mexico City | |
| Mexico | 4840021 - Universidad Autonoma de Nuevo Leon - Hospital Universitario | Monterrey | |
| Mexico | 4840036 - Cardiolink Clin Trials, SC. | Monterrey | |
| Mexico | 4840045 - OCA Hospital - Monterrey International Research Center | Monterrey | |
| Mexico | 4840007 - Unidad de Prevención y Atención Cardiometabólica (UPAC) | Morelia | |
| Mexico | 4840074 - Unidad de Investigación y Salud de Puebla S.C. | Puebla | |
| Mexico | 4840003 - Centro de Estudios Clínicos de Querétaro, SC | Querétaro | |
| Mexico | 4840022 - Centro de Atencion e Investigacion Cardiovascular del Potosi | San Luis Potosi | |
| Mexico | 4840025 - Hospital Central "Dr. Ignacio Morones Prieto" | San Luis Potosí | |
| Mexico | 4840076 - CIMAB S.A. de C.V. | Torreón | |
| Mexico | 4840018 - Centro de Alta Especialidad Dr. Rafael Lucio | Xalapa | |
| Netherlands | 5280054 - Noordwest Ziekenhuisgroep - Alkmaar | Alkmaar | |
| Netherlands | 5280031 - Meander Medisch Centrum - Locatie Amersfoort | Amersfoort | |
| Netherlands | 5280016 - Onze Lieve Vrouwe Gasthuis | Amsterdam | |
| Netherlands | 5280039 - OLVG Location West | Amsterdam | |
| Netherlands | 5280057 - Bovenij ziekenhuis | Amsterdam | |
| Netherlands | 5280061 - Amsterdam UMC - VUMC | Amsterdam | |
| Netherlands | 5280048 - Amphia Zienkenhuis - Locatie Molengracht Breda | Breda | |
| Netherlands | 5280047 - Deventer Hospital | Deventer | |
| Netherlands | 5280013 - Ziekenhuis Gelderse Vallei | Ede | |
| Netherlands | 5280040 - Maxima Medisch Centrum | Eindhoven | |
| Netherlands | 5280049 - Medisch Spectrum Twente | Enschede | |
| Netherlands | 5280038 - Admiraal de Ruijter Ziekenhuis - Locatie Goes | Goes | |
| Netherlands | 5280056 - Groene Hart Ziekenhuis - Gouda | Gouda | |
| Netherlands | 5280034 - Spaarne Gasthuis | Haarlem | |
| Netherlands | 5280052 - Ziekenhuis St Jansdal | Harderwijk | |
| Netherlands | 5280063 - Zuyderland Medisch Centrum, Heerlen | Heerlen | |
| Netherlands | 5280037 - Dijklander Ziekenhuis - Hoorn | Hoorn | |
| Netherlands | 5280045 - Medisch Centrum Leeuwarden | Leeuwarden | |
| Netherlands | 5280064 - Alrijne Ziekenhuis Leiden | Leiden | |
| Netherlands | 5280036 - Canisius-Wilhelmina Ziekenhuis | Nijmegen | |
| Netherlands | 5280043 - Radboud UMC | Nijmegen | |
| Netherlands | 5280018 - Maasstad Ziekenhuis | Rotterdam | |
| Netherlands | 5280062 - Sint Franciscus Gasthuis | Rotterdam | |
| Netherlands | 5280035 - D & A Research | Sneek | |
| Netherlands | 5280060 - Ziekenhuis Rivierenland - Cardiologie | Tiel | |
| Netherlands | 5280042 - Elisabeth TweeSteden Ziekenhuis Vestiging Tilburg | Tilburg | |
| Netherlands | 5280058 - Universitair Medisch Centrum Utrecht | Utrecht | |
| Netherlands | 5280020 - VieCuri | Venlo | |
| Netherlands | 5280046 - Gelre Ziekenhuizen - Zutphen | Zutphen | |
| New Zealand | 5540004 - Middlemore Hospital | Auckland | |
| New Zealand | 5540017 - Auckland City Hospital | Auckland | |
| New Zealand | 5540008 - Christchurch Hospital | Christchurch | |
| New Zealand | 5540009 - Dunedin Hospital | Dunedin | |
| New Zealand | 5540005 - Waikato Hospital | Hamilton | |
| New Zealand | 5540007 - Taranaki Base Hospital | New Plymouth | |
| New Zealand | 5540011 - Wellington Hospital | Newtown | Wellington |
| New Zealand | 5540010 - North Shore Hospital | Takapuna | Auckland |
| Norway | 5780003 - Akershus Universitetssykehus HF | Lørenskog | |
| Norway | 5780011 - Diakonhjemmet Sykehus | Oslo | |
| Norway | 5780010 - Sykehuset Telemark HF - Skien | Skien | |
| Norway | 5780006 - Helse Stavanger HF | Stavanger | |
| Peru | 6040017 - Clinica El Golf | Lima | |
| Peru | 6040031 - Clínica Internacional - Sede San Borja | Lima | |
| Peru | 6040056 - Instituto Nacional Cardiovascular - INCOR | Lima | |
| Poland | 6160082 - II Oddzial Kardiologiczny PAKS | Bielsko-Biala | |
| Poland | 6160063 - Klinika Kardiologii i Kardiochirurgii 10 WSK | Bydgoszcz | |
| Poland | 6160081 - McSn | Chrzanow | |
| Poland | 6160065 - III Oddzial Kardiologii Inwazyjnej, Angiologii i Elektrokard | Dabrowa Górnicza | |
| Poland | 6160054 - SPS Szpital Zachodni | Grodzisk Mazowiecki | |
| Poland | 6160066 - IV Oddzial Kardiologii Inwazyjnej, Elektrostymulacji i Angio | Kedzierzyn-Kozle | |
| Poland | 6160078 - Nowy Szpital Uniwersytecki w Krakowie-Prokocimiu | Krakow | |
| Poland | 6160051 - Krakowski Szpital Specjalistyczny im. Jana Pawla II | Kraków | |
| Poland | 6160095 - Centrum Kardiologii Inwazyjnej i Angiologii w Krosnie | Krosno | |
| Poland | 6160096 - 1 Wojskowy Szpital Kliniczny z Poliklinika SPZOZ w Lublinie | Lublin | |
| Poland | 6160062 - Wielospecjalistyczny Szpital Samodzielny Publiczny Zaklad Op | Nowa Sól | |
| Poland | 6160064 - Medicome sp.zoo | Oswiecim | |
| Poland | 6160100 - Centrum Kardiologii Inwazyjnej, Elektroterapii i Angiologii | Pinczów | |
| Poland | 6160077 - Samodzielny Publiczny Zaklad Opieki Zdrowotnej w Pulawach | Pulawy | |
| Poland | 6160088 - Ikardia | Pulawy | |
| Poland | 6160080 - Regional Public Specialty Hospital "Latawiec" | Swidnica | |
| Poland | 6160067 - Szpital Polski - Sztum | Sztum | |
| Poland | 6160061 - Wojewódzki Szpital Zespolony im. Ludwika Rydygiera w Toruniu | Torun | |
| Poland | 6160073 - American Heart of Poland | Tychy | |
| Poland | 6160093 - Specjalistyczny Szpital im. dr Alfreda Sokolowskiego | Walbrzych | |
| Poland | 6160052 - Szpital Wolski | Warszawa | |
| Poland | 6160075 - Szpital Bielanski | Warszawa | |
| Poland | 6160086 - Dept. of Interventional cardiology and Angiology, Institute | Warszawa | |
| Poland | 6160083 - Wojewódzki Szpital Specjalistyczny im. Marii Sklodowskiej-Curie | Zgierz | |
| Portugal | 6200011 - Hospital Garcia de Orta, EPE | Almada | |
| Portugal | 6200026 - Centro Hospitalar do Baixo Vouga | Aveiro | |
| Portugal | 6200015 - Hospital de Braga | Braga | |
| Portugal | 6200018 - Centro Hospitalar e Universitário de Coimbra, EPE - Hospitai | Coimbra | |
| Portugal | 6200022 - Centro Hospitalar e Universitário de Coimbra, EPE - Hospital | Coimbra | |
| Portugal | 6200012 - Centro Hospitalar e Universitário do Algarve, EPE - Hospital | Faro | |
| Portugal | 6200021 - Centro Hospitalar do Alto Ave, EPE | Guimarães | |
| Portugal | 6200009 - Hospital de Santo Andre | Leiria | |
| Portugal | 6200014 - Centro Hospitalar de Lisboa Ocidental, EPE - Hospital Santa | Oeiras | |
| Portugal | 6200025 - Unidade Local de Saude de Matosinhos - Hospital Pedro Hispan | Senhora Da Hora | |
| Portugal | 6200017 - Centro Hospitalar de Trás-os-Montes e Alto Douro, EPE - Hospital | Vila Real | |
| Romania | 6420052 - Spitalul Judetean de Urgenta "Dr. Constantin Opris" Baia Mar | Baia Mare | |
| Romania | 6420053 - Spitalul Clinic Judetean de Urgenta Brasov | Brasov | |
| Romania | 6420050 - Spitalul Universitar de Urgent | Bucarest | |
| Romania | 6420043 - Spitalul Universitar de Urgenta Bucuresti | Bucuresti | |
| Romania | 6420046 - Spitalului Universitar de Urgenta Militar Central "Dr. Carol Davila" | Bucuresti | |
| Romania | 6420090 - Spitalul Clinic de Urgenta "Bagdasar-Arseni" | Bucuresti | |
| Romania | 6420051 - Institutul Inimii "Niculae Stancioiu" | Cluj-Napoca | |
| Romania | 6420060 - Spitalul Clinic Judetean de Urgenta Cluj-Napoca | Cluj-Napoca | |
| Romania | 6420080 - Spitalul Clinic de Recuperare Cluj-Napoca | Cluj-Napoca | |
| Romania | 6420088 - Institutul Inimii "Niculae Stancioiu" | Cluj-Napoca | |
| Romania | 6420044 - Spitalul Clinic Judetean de Ur | Craiova | |
| Romania | 6420057 - Institutul de Boli Cardiovasculare "Prof. Dr. George I. M. Georgescu | Iasi | |
| Romania | 6420045 - Spitalul Clinic Judetean de Urgenta Oradea | Oradea | |
| Romania | 6420048 - Spitalul Judetean de Urgenta Pitesti-Arges | Pitesti | |
| Romania | 6420079 - Spitalul Clinic Judetean de Urgenta Sibiu | Sibiu | |
| Romania | 6420047 - Spitalul de Urgenta "Sf. Ioan Cel Nou" Suceava | Suceava | |
| Romania | 6420049 - Spitalul Clinic Judetean de Urgenta Tîrgu - Mures | Târgu-Mures | |
| Romania | 6420059 - Institutul de Urgenta pentru Boli Cardiovasculare si Transplant | Târgu-Mures | |
| Romania | 6420071 - Institutului de Boli Cardiovasculare Timisoara | Timisoara | |
| Romania | 6420083 - Institutului de Boli Cardiovasculare Timisoara | Timisoara | |
| Russian Federation | 6430075 - First City Clinical Hospital named after E. E. Volosevich | Arkhangel'sk | |
| Russian Federation | 6430060 - Regional State Budgetary Institution of Public Health | Barnaul | |
| Russian Federation | 6430069 - Regional Clinical Hospital | Barnaul | |
| Russian Federation | 6430108 - Novaya Bolnitsa | Ekaterinburg | |
| Russian Federation | 6430068 - Regional Budgetary Healthcare Institution "Cardiology Dispensary" | Ivanovo | |
| Russian Federation | 6430116 - City hospital # 2 "Sosnovaya roscha" | Kaluga | |
| Russian Federation | 6430079 - Scientific-Research Institute of Complex Problems of Cardio | Kemerovo | |
| Russian Federation | 6430048 - City Clinical Hospital No. 6 named after Karpovicha | Krasnoyarsk | |
| Russian Federation | 6430050 - Kursk City Emergency Care Hospital | Kursk | |
| Russian Federation | 6430063 - Lyubertsy Regional Hospital No. 2 | Lyubertsy | |
| Russian Federation | 6430105 - City Clinical Hospital No. 51 | Moscow | |
| Russian Federation | 6430091 - City clinical hospital #15 n.a. O.M. Filatov | Moskva | |
| Russian Federation | 6430080 - City Clinical Hospital No. 5 | Nizhniy Novgorod | |
| Russian Federation | 6430047 - Novosibirsk Regional Clinical Hospital | Novosibirsk | |
| Russian Federation | 6430058 - State Budget Healthcare Institution of Novosibirsk Region "C | Novosibirsk | |
| Russian Federation | 6430110 - SBHI of Novosibirsk Region "City Clinical Hospital of Emergency Care #2" | Novosibirsk | |
| Russian Federation | 6430045 - Penza Regional Clinical Hospital n.a. N.N.Burdenko | Penza | |
| Russian Federation | 6430054 - City Clinical Hospital No. 4 | Perm | |
| Russian Federation | 6430064 - City Hospital for Emergency Care of Rostov-on-Don | Rostov-on-Don | |
| Russian Federation | 6430049 - Pokrovskaya Municipal Hospital | Saint Petersburg | |
| Russian Federation | 6430072 - Samara Regional Cardiology Dispensary | Samara | |
| Russian Federation | 6430070 - Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine | Sankt-Peterburg | |
| Russian Federation | 6430074 - St. Petersburg State Institution of Healthcare | Sankt-Peterburg | |
| Russian Federation | 6430081 - Saint Petersburg State Medical Academy | Sankt-Peterburg | |
| Russian Federation | 6430107 - Clinical Hospital of the Russian Academy of Science | Sankt-Peterburg | |
| Russian Federation | 6430115 - Pavlov First Saint Petersburg State Medical University | Sankt-Peterburg | |
| Russian Federation | 6430067 - Saratov State Medical University named after V.I. Razumovsky | Saratov | |
| Russian Federation | 6430042 - Research Institute of Cardiology | Tomsk | |
| Russian Federation | 6430043 - Tula Regional Clinical Hospital | Tula | |
| Russian Federation | 6430053 - Tyumen Cardiology Center | Tyumen | |
| Russian Federation | 6430092 - Yaroslavl Regional Clinical Hospital | Yaroslavl | |
| Russian Federation | 6430111 - Clinical Hospital No. 8 | Yaroslavl' | |
| Serbia | 6880008 - Clinical Center of Serbia -- Division of Cardiology | Belgrade | |
| Serbia | 6880009 - Department of Cardiology, Clinical Center of Serbia and Belgrade | Belgrade | |
| Serbia | 6880014 - Klinicki Centar Srbije | Belgrade | Savski Venac |
| Serbia | 6880019 - KBC "Dr Dragiša Mišovic-Dedinje" | Belgrade | |
| Serbia | 6880023 - Klinicko Bolnicki Centar Zvezdara | Belgrade | |
| Serbia | 6880010 - Klinicki Centar Kragujevac | Kragujevac | |
| Serbia | 6880015 - General Hospital Leskovac | Leskovac | |
| Serbia | 6880016 - Klinicki Centar Niš | Niš | |
| Serbia | 6880026 - Opšta Bolnica Pancevo | Pancevo | |
| Serbia | 6880018 - Klinicki Centar Srbije | Savski Venac | |
| Serbia | 6880012 - Institute of Cardiovascular Diseases of Vojvodina | Sremska Kamenica | |
| Serbia | 6880013 - General Hospital Sremska Mitrovica | Sremska Mitrovica | |
| Serbia | 6880027 - General Hospital Subotica | Subotica | |
| Serbia | 6880020 - Zdravstveni Centar Užice | Uzice | |
| Serbia | 6880025 - General Hospital Valjevo | Valjevo | |
| Serbia | 6880024 - Opsta Bolnica "Dorde Joanovic" Zrenjanin | Zrenjanin | |
| Singapore | 7020005 - National University Hospital (S) Pte Ltd | Singapore | |
| Singapore | 7020006 - National Heart Center Singapore | Singapore | |
| Slovakia | 7030006 - Univerzitna Nemocnica Bratislava - Nemocnica Staré Mesto | Bratislava | |
| Slovakia | 7030014 - Univerzitna Nemocnica Bratislava - Nemocnica sv. Cyrila a Me | Bratislava | |
| Slovakia | 7030013 - Nemocnica Malacky | Malacky | |
| Slovakia | 7030003 - Kardiocentrum Nitra s.r.o. | Nitra | |
| Slovakia | 7030002 - Svet zdravia, a.s. - Všeobecná nemocnica Rimavská Sobota | Rimavská Sobota | |
| South Africa | 7100019 - Groote Schuur Hospital | Cape Town | |
| South Africa | 7100023 - Tread Research | Cape Town | |
| South Africa | 7100017 - Netcare Union Hospital | Johannesburg | |
| South Africa | 7100007 - Netcare Unitas Hospital | Lyttelton | Centurion |
| South Africa | 7100012 - Netcare Unitas Hospital | Lyttelton | Centurion |
| South Africa | 7100006 - Mediclinic Vergelegen | Somerset West | Cape Town |
| South Africa | 7100022 - Mediclinic Vergelegen | Somerset West | Cape Town |
| South Africa | 7100020 - Netcare Sunninghill Hospital | Sunninghill | |
| South Africa | 7100010 - Clinical Projects Research SA (Pty) Ltd. | Worcester | |
| Spain | 7240035 - Complexo Hospitalario Universitario A Coruña | A Coruña | |
| Spain | 7240043 - Hospital Universitario Fundación Alcorcón | Alcorcón | |
| Spain | 7240064 - Hospital General Universitario de Alicante | Alicante | |
| Spain | 7240033 - Hospital Clínic de Barcelona | Barcelona | |
| Spain | 7240050 - Hospital de la Santa Creu i Sant Pau | Barcelona | |
| Spain | 7240062 - Hospital del Mar | Barcelona | |
| Spain | 7240063 - Hospital Universitario Vall d'Hebron | Barcelona | |
| Spain | 7240076 - Hospital Juan Ramón Jiménez | Huelva | |
| Spain | 7240053 - Hospital Universitari de Bellvitge (IDIBELL) | L'hospitalet de Llobregat | |
| Spain | 7240077 - Hospital Universitari Arnau de Vilanova de Lleida | Lleida | |
| Spain | 7240045 - Hospital Universitario Ramón y Cajal | Madrid | |
| Spain | 7240070 - Hospital Universitario Virgen Arrixaca | Murcia | |
| Spain | 7240068 - Hospital Universitario Marqués de Valdecilla | Santander | |
| Spain | 7240032 - Hospital Universitari Joan XXIII de Tarragona | Tarragona | |
| Spain | 7240034 - Hospital Clinico Universitario de Valencia | Valencia | |
| Spain | 7240100 - Hospital Álvaro Cunqueiro | Vigo | |
| Sweden | 7520023 - Örebro University Hospital | Örebro | |
| Sweden | 7520024 - Ostersunds Sjukhus | Östersund | |
| Sweden | 7520011 - Karolinska Universitetssjukhuset - Huddinge | Stockholm | |
| Sweden | 7520015 - Västmanlands Sjukhus Västerås | Västerås | |
| Switzerland | 7560025 - University Hospital | Basel | |
| Switzerland | 7560014 - Cardiocentro Ticino | Lugano | |
| Switzerland | 7560019 - Stadtspital Triemli | Zürich | |
| Taiwan | 1580001 - Kaohsiung Medical University Chung-Ho Memorial Hospital | Kaohsiung | |
| Taiwan | 1580002 - Kaohsiung Veterans General Hospital | Kaohsiung | |
| Taiwan | 1580006 - E-Da Hospital | Kaohsiung | |
| Taiwan | 1580008 - Mackay Memorial Hospital - Tamsui Branch | New Taipei City | |
| Taiwan | 1580010 - China Medical University Hospital | Taichung City | |
| Taiwan | 1580007 - Chi Mei Medical Center | Tainan | |
| Taiwan | 1580004 - Shin Kong Wu Ho-Su Memorial Hospital | Taipei | |
| Taiwan | 1580012 - Cheng Hsin General Hospital | Taipei City | Beitou |
| Taiwan | 1580009 - National Taiwan University Hospital | Zhongzheng | |
| Thailand | 7640012 - Ramathibodi Hospital | Bangkok | |
| Thailand | 7640021 - Chiang Mai University | Chiang Mai | |
| Thailand | 7640017 - Khon Kaen University (KKU) | Khon Kaen | |
| Thailand | 7640018 - Maharat Nakhon Ratchasima Hospital | Nakhon Ratchasima | |
| Thailand | 7640010 - King Chulalongkorn Memorial Hospital | Pathum Wan | |
| Thailand | 7640014 - Police General Hospital | Pathum Wan | |
| Thailand | 7640020 - Buddhachinaraj Hospital Phitsanuloke | Phitsanulok | |
| Thailand | 7640009 - Songklanagarind Hospital | Songkhla | |
| Turkey | 7920024 - Afyon Kocatepe University Medical Faculty Dept. Of Cardiology | Afyonkarahisar | |
| Turkey | 7920030 - T. C. Saglik Bakanligi - Bagcilar Egitim ve Arastirma Hastan | Bagcilar | |
| Turkey | 7920018 - Cukurova University School Of Medicine Balcali Hospital | Balcali | |
| Turkey | 7920023 - Ege Üniversitesi Tip Fakültesi | Bornova | |
| Turkey | 7920016 - Ankara Sehir Hastanesi Bilkent | Çankaya | |
| Turkey | 7920021 - Istanbul Universitesi Istanbul Tip Fakultesi | Çapa | |
| Turkey | 7920017 - Eskisehir Osmangazi Üniversitesi Tip Fakültesi | Eskisehir | |
| Turkey | 7920012 - Istanbul Universitesi Cerrahpasa Tip Fakultesi Hastanesi | Fatih | |
| Turkey | 7920022 - Marmara Universitesi Tip Fakultesi | Istanbul | |
| Turkey | 7920032 - Kocaeli Universitesi Tip Fakultesi - Kardiyoloji Anabilim Dali Baskani | Kocaeli | |
| Turkey | 7920015 - T.C. Saglik Bakanligi - Kartal Kosuyolu Yuksek Ihtisas Egitim | Maltepe | |
| Turkey | 7920014 - Mersin Üniversitesi Tip Fakültesi | Mersin | |
| Turkey | 7920026 - Ondokuz Mayis Üniversitesi - Kardiyoloji Anabilim Dali | Samsun | |
| Turkey | 7920025 - Bursa Yüksek Ihtisas Egitim ve Arastirma Hastanesi - Kardiyo | Yildirim | |
| Ukraine | 8040019 - Cherkasy Regional Cardiological Center | Cherkasy | |
| Ukraine | 8040010 - Dnipropetrovsk Medical Academy, Dnipropetrovsk Joint Emergen | Dnipro | |
| Ukraine | 8040032 - Ivano-Frankivskyy oblasnyy klinichnyy kardiologichnyy dyspan | Ivano-Frankivsk | |
| Ukraine | 8040037 - The Ivano-Frankivsk National Medical Univeristy | Ivano-Frankivsk | |
| Ukraine | 8040012 - Kharkiv City Clinical Hospital #8 | Kharkiv | |
| Ukraine | 8040017 - National Institute of Therapy named after L.T. Malaya NAMS o | Kharkiv | |
| Ukraine | 8040048 - Communal Institution of Healthcare "Kharkiv Municipal Clinic | Kharkiv | |
| Ukraine | 8040050 - Regional Clinical Hospital - Emergency Medical Care | Kharkiv | |
| Ukraine | 8040013 - Khmelnytskyi Regional Hospital | Khmelnytskyi | |
| Ukraine | 8040008 - Kyiv City Clinical Hospital No. 1 | Kyiv | |
| Ukraine | 8040009 - Kiev City Clinical Hospital No. 5 | Kyiv | |
| Ukraine | 8040021 - Heart Institute of the Ministry of Health of Ukraine | Kyiv | |
| Ukraine | 8040025 - National Scientific Center | Kyiv | |
| Ukraine | 8040047 - Oleksandrivska Clinical Hospital | Kyiv | |
| Ukraine | 8040049 - Lutsk City Clinical Hospital | Lutsk | |
| Ukraine | 8040016 - Lviv National Medical University named by Danylo Halitskyy | Lviv | |
| Ukraine | 8040035 - Lviv Regional State Clinical-and-Diagnostic Cardiology Cente | Lviv | |
| Ukraine | 8040038 - City Hospital 4 | Mykolaiv | |
| Ukraine | 8040014 - Odessa Regional Hospital | Odesa | |
| Ukraine | 8040015 - Ternopil University Hospital | Ternopil | |
| Ukraine | 8040020 - Uzhgorod National University | Uzhgorod | |
| Ukraine | 8040036 - Regional Medical Center for Cardiovascular Diseases | Zaporizhzhia | |
| Ukraine | 8040023 - Zhitomir Regional Clinical Hospital | Zhytomyr | |
| United Kingdom | 8260102 - Queen Elizabeth Hospital Birmingham | Birmingham | |
| United Kingdom | 8260057 - Mid Essex Hospital Services NHS Trust - Broomfield Hospital | Chelmsford | |
| United Kingdom | 8260071 - Ashford and St Peter's Hospitals NHS Foundation Trust | Chertsey | |
| United Kingdom | 8260055 - NHS National Waiting Times Centre Golden Jubilee National Hospital | Clydebank | |
| United Kingdom | 8260058 - Royal Devon & Exeter NHS Foundation Trust | Exeter | |
| United Kingdom | 8260093 - The London North West Healthcare NHS Trust - Northwick Park | Harrow | |
| United Kingdom | 8260088 - Kettering General Hospital NHS Foundation Trust | Kettering | |
| United Kingdom | 8260043 - University Hospitals of Leicester NHS Trust - Glenfield | Leicester | |
| United Kingdom | 8260101 - United Lincolnshire Hospitals NHS Trust - Lincoln County Hospital | Lincoln | |
| United Kingdom | 8260086 - Manchester University NHS Foundation Trust - Manchester Royal Infirmary | Manchester | |
| United Kingdom | 8260065 - Milton Keynes Hospital NHS Foundation Trust | Milton Keynes | |
| United Kingdom | 8260134 - The Newcastle upon Tyne Hospitals NHS Foundation Trust - Fre | Newcastle upon Tyne | |
| United Kingdom | 8260068 - Morriston Hospital | Swansea | |
| United Kingdom | 8260066 - Torbay and South Devon NHS Foundation Trust - Torbay Hospital | Torquay | |
| United Kingdom | 8260099 - The Royal Wolverhampton NHS Trust - New Cross Hospital | Wolverhampton | |
| United States | 8401042 - Abington Medical Specialists | Abington | Pennsylvania |
| United States | 8400657 - Summa Health | Akron | Ohio |
| United States | 8400896 - Advanced Cardiovascular LLC | Alexander City | Alabama |
| United States | 8400368 - Cambridge Medical Trials | Alexandria | Louisiana |
| United States | 8400595 - Lehigh Valley Hospital | Allentown | Pennsylvania |
| United States | 8400482 - Amarillo Heart Clinical Research Institute | Amarillo | Texas |
| United States | 8400805 - PharmaTex Research | Amarillo | Texas |
| United States | 8400618 - McFarland Clinic, PC | Ames | Iowa |
| United States | 8400591 - AnMed Health Medical Center | Anderson | South Carolina |
| United States | 8401142 - Anne Arundel Health System | Annapolis | Maryland |
| United States | 8401185 - Piedmont Heart Institute | Athens | Georgia |
| United States | 8400376 - Emory University | Atlanta | Georgia |
| United States | 8400918 - Augusta University | Augusta | Georgia |
| United States | 8400574 - Aurora Denver Cardiology Associates | Aurora | Colorado |
| United States | 8401054 - Central Cardiology Medical Center | Bakersfield | California |
| United States | 8400483 - Eastern Maine Medical Center | Bangor | Maine |
| United States | 8400350 - Cardiology, PC | Birmingham | Alabama |
| United States | 8400357 - Saint Luke's Boise Medical Center | Boise | Idaho |
| United States | 8400998 - Beth Israel Deaconess Medical Center | Boston | Massachusetts |
| United States | 8400545 - Advanced Heart Care LLC | Bridgewater | New Jersey |
| United States | 8400626 - Montefiore Medical Center - Albert Einstein College of Medicine | Bronx | New York |
| United States | 8400636 - Jacobi Medical Center | Bronx | New York |
| United States | 8400360 - Buffalo Heart Group | Buffalo | New York |
| United States | 8401028 - Buffalo V.A. Medical Center | Buffalo | New York |
| United States | 8400835 - Cooper University Hospital | Camden | New Jersey |
| United States | 8400836 - Our Lady of Lourdes Medical Center | Camden | New Jersey |
| United States | 8400608 - Holy Spirit Cardiology | Camp Hill | Pennsylvania |
| United States | 8400793 - Aultman Hospital | Canton | Ohio |
| United States | 8400872 - Chambersburg Hospital | Chambersburg | Pennsylvania |
| United States | 8401027 - UNC Hospitals Heart and Vascular Center at Meadowmont | Chapel Hill | North Carolina |
| United States | 8400733 - Novant Health Heart and Vascular Institute | Charlotte | North Carolina |
| United States | 8400854 - The Chattanooga Heart Institute | Chattanooga | Tennessee |
| United States | 8400610 - Jesse Brown V.A. Medical Center | Chicago | Illinois |
| United States | 8400858 - University of Cincinnati | Cincinnati | Ohio |
| United States | 8401233 - Cincinnati V.A. Medical Center | Cincinnati | Ohio |
| United States | 8400484 - Clearwater Cardiovascular and Interventional Consultants | Clearwater | Florida |
| United States | 8400966 - MetroHealth System | Cleveland | Ohio |
| United States | 8400684 - UCHealth Memorial Hospital Central - Colorado Springs | Colorado Springs | Colorado |
| United States | 8401108 - University of Missouri Health System | Columbia | Missouri |
| United States | 8400849 - IACT Health | Columbus | Georgia |
| United States | 8400379 - John Muir Health and Cardiovascular Institute | Concord | California |
| United States | 8400931 - Valley Clinical Trials | Covina | California |
| United States | 8400862 - Cardiovascular Associates Research | Covington | Louisiana |
| United States | 8400485 - V.A. North Texas Health Care System | Dallas | Texas |
| United States | 8400371 - Danbury Hospital | Danbury | Connecticut |
| United States | 8400565 - Miami Valley Hospital | Dayton | Ohio |
| United States | 8400544 - Cardiology Research Associates | Daytona Beach | Florida |
| United States | 8400655 - Atlanta V.A. Medical Center | Decatur | Georgia |
| United States | 8400577 - Doylestown Cardiology Associates | Doylestown | Pennsylvania |
| United States | 8400488 - Essentia Health | Duluth | Minnesota |
| United States | 8400920 - Saint Lukes Hospital | Duluth | Minnesota |
| United States | 8400489 - Duke University Hospital | Durham | North Carolina |
| United States | 8400361 - Midwest Cardiovascular Research | Elkhart | Indiana |
| United States | 8400654 - North Ohio Research Ltd. | Elyria | Ohio |
| United States | 8400930 - Lake Internal Medicine Assoc. | Eustis | Florida |
| United States | 8401093 - Advanced Heart Care Group | Fairview Heights | Illinois |
| United States | 8401064 - Inova Fairfax Hospital | Falls Church | Virginia |
| United States | 8400651 - Sanford Medical Center Fargo | Fargo | North Dakota |
| United States | 8400613 - Jim Moran Heart and Vascular Center | Fort Lauderdale | Florida |
| United States | 8401010 - Integrative Research Associates Inc. | Fort Lauderdale | Florida |
| United States | 8400911 - Brooke Army Medical Center | Fort Sam Houston | Texas |
| United States | 8401103 - Orange Coast Memorial Hospital | Fountain Valley | California |
| United States | 8400490 - University of Florida | Gainesville | Florida |
| United States | 8401120 - Northeast Georgia Medical Center | Gainesville | Georgia |
| United States | 8400556 - Mercy Gilbert Medical Center | Gilbert | Arizona |
| United States | 8400769 - Healthy Heart Cardiology | Grandville | Michigan |
| United States | 8400997 - CardioVascular Institute of North Colorado Cardiology Clinic | Greeley | Colorado |
| United States | 8400491 - Moses H. Cone Memorial Hospital | Greensboro | North Carolina |
| United States | 8401055 - Upstate Cardiology, PA | Greenville | South Carolina |
| United States | 8401171 - Greenville Hospital System | Greenville | South Carolina |
| United States | 8400496 - Advanced Cardiology Associates | Greenwood | South Carolina |
| United States | 8400324 - Milton Hershey Medical Center | Hershey | Pennsylvania |
| United States | 8400366 - High Point Regional Hospital | High Point | North Carolina |
| United States | 8401104 - Cardiovascular Institute of the South | Houma | Louisiana |
| United States | 8400337 - Heart Center Research, LLC | Huntsville | Alabama |
| United States | 8400507 - The Saint Vincent Heart Center of Indiana | Indianapolis | Indiana |
| United States | 8400961 - Indiana Heart Physicians, Inc. | Indianapolis | Indiana |
| United States | 8400989 - Indiana Heart Hospital | Indianapolis | Indiana |
| United States | 8401168 - Jackson Heart Clinic | Jackson | Mississippi |
| United States | 8400517 - Shands Jacksonville Medical Center | Jacksonville | Florida |
| United States | 8400645 - NEA Baptist Clinic | Jonesboro | Arkansas |
| United States | 8401141 - Western Michigan University Homer Striker MD School of Medicine | Kalamazoo | Michigan |
| United States | 8400091 - Glacier View Cardiology | Kalispell | Montana |
| United States | 8400648 - Saint Luke's Cardiovascular Consultants | Kansas City | Missouri |
| United States | 8400500 - Tennova Health Care - Turkey Creek Medical Center | Knoxville | Tennessee |
| United States | 8401166 - Sharp Grossmont Hospital | La Mesa | California |
| United States | 8400563 - Cardiovascular Institute of the South | Lafayette | Louisiana |
| United States | 8401192 - South Orange County Surgical Medical Group | Laguna Hills | California |
| United States | 8400344 - Lancaster General Hospital | Lancaster | Pennsylvania |
| United States | 8400582 - Carolina Heart Specialists | Lancaster | South Carolina |
| United States | 8400689 - University Medical Center | Las Vegas | Nevada |
| United States | 8400783 - Nebraska Heart Institute | Lincoln | Nebraska |
| United States | 8400975 - Central Arkansas Veterans Healthcare System | Little Rock | Arkansas |
| United States | 8400677 - Saint Joseph's Hospital Cardiac Catheterization Associates | Liverpool | New York |
| United States | 8400596 - Long Beach Memorial Medical Center | Long Beach | California |
| United States | 8400910 - Cardiovascular Innovation and Research Center | Long Beach | California |
| United States | 8400597 - Los Alamitos Cardiovascular | Los Alamitos | California |
| United States | 8400693 - University of California Los Angeles | Los Angeles | California |
| United States | 8400717 - V.A. Greater Los Angeles Healthcare System | Los Angeles | California |
| United States | 8400661 - Norton Cardiovascular Associates | Louisville | Kentucky |
| United States | 8400670 - Medical Center of the Rockies | Loveland | Colorado |
| United States | 8400916 - Southeastern Cardiology & Cardiovascular Clinic | Lumberton | North Carolina |
| United States | 8400502 - Stroobants Cardiovascular Center | Lynchburg | Virginia |
| United States | 8400503 - The Heart and Vascular Center / Holy Family Memorial | Manitowoc | Wisconsin |
| United States | 8400887 - Matthews Medical Center | Matthews | North Carolina |
| United States | 8400881 - North Texas Research Associates | McKinney | Texas |
| United States | 8401231 - Revival Research Institute | McKinney | Texas |
| United States | 8400760 - V.A. Medical Center - Memphis | Memphis | Tennessee |
| United States | 8400873 - Baptist Clinical Research Institute | Memphis | Tennessee |
| United States | 8400985 - Optimus U Corp. | Miami | Florida |
| United States | 8400638 - Mid Michigan Regional Medical Center | Midland | Michigan |
| United States | 8400364 - Minneapolis Heart Institute Foundation | Minneapolis | Minnesota |
| United States | 8400682 - Trinity Medical Group | Minot | North Dakota |
| United States | 8400888 - Saint Jude Heritage Healthcare | Mission Viejo | California |
| United States | 8400713 - University of South Alabama College of Medicine | Mobile | Alabama |
| United States | 8400576 - IU Health Ball Memorial Hospital Physicians, Inc | Muncie | Indiana |
| United States | 8400801 - Centennial Medical Center | Nashville | Tennessee |
| United States | 8401178 - Jersey Shore University Medical Center Meridian Health | Neptune | New Jersey |
| United States | 8400921 - Mission Research Institute, LLC | New Braunfels | Texas |
| United States | 8401127 - Tulane University Health Science Center | New Orleans | Louisiana |
| United States | 8400380 - Mount Sinai Medical Center | New York | New York |
| United States | 8401119 - Lenox Hill Hospital | New York | New York |
| United States | 8401134 - Christiana Hospital | Newark | Delaware |
| United States | 8401144 - Saint Michael's Medical Center | Newark | New Jersey |
| United States | 8400745 - Hoag Memorial Hospital Presbyterian | Newport Beach | California |
| United States | 8400631 - North Kansas City Hospital | North Kansas City | Missouri |
| United States | 8400658 - Valley Clinical Trials, Inc. | Northridge | California |
| United States | 8400735 - Parkway Cardiology Associates, PC | Oak Ridge | Tennessee |
| United States | 8400504 - Integris Baptist Medical Center | Oklahoma City | Oklahoma |
| United States | 8400936 - South Oklahoma Heart Research | Oklahoma City | Oklahoma |
| United States | 8400978 - Midwest Heart and Vascular | Overland Park | Kansas |
| United States | 8400543 - Cardiology Partners Research Institute | Palm Beach Gardens | Florida |
| United States | 8401000 - Advocate Lutheran General Hospital | Park Ridge | Illinois |
| United States | 8400720 - Valley Clinical Trials | Pasadena | California |
| United States | 8400542 - Cardiology Consultants | Pensacola | Florida |
| United States | 8400785 - OSF Multi-Specialty Group | Peoria | Illinois |
| United States | 8400746 - Penn Presbyterian Medical Center | Philadelphia | Pennsylvania |
| United States | 8400747 - Phoenix V.A. Health Care System | Phoenix | Arizona |
| United States | 8400772 - Mayo Clinic Arizona | Phoenix | Arizona |
| United States | 8400718 - V.A. Pittsburgh Healthcare System | Pittsburgh | Pennsylvania |
| United States | 8400572 - AtlantiCare Regional Medical Center | Pomona | New Jersey |
| United States | 8401092 - Saint Joseph Mercy Oakland | Pontiac | Michigan |
| United States | 8400812 - Maine Medical Center Bramhall Campus | Portland | Maine |
| United States | 8400551 - Cardiovascular Research of Knoxville | Powell | Tennessee |
| United States | 8400811 - Rhode Island Hospital | Providence | Rhode Island |
| United States | 8400628 - Multicare Health System | Puyallup | Washington |
| United States | 8400889 - NC Heart and Vascular Research | Raleigh | North Carolina |
| United States | 8400320 - Black Hills Cardiovascular Research | Rapid City | South Dakota |
| United States | 8400601 - McGuire Research Institute | Richmond | Virginia |
| United States | 8400882 - Reid Health | Richmond | Indiana |
| United States | 8400787 - Riverside Community Hospital | Riverside | California |
| United States | 8400847 - University of Rochester Medical Center-Strong Memorial Hospital | Rochester | New York |
| United States | 8400861 - Ascension Providence Rochester Hospital | Rochester | Michigan |
| United States | 8401154 - Rochester General Hospital | Rochester | New York |
| United States | 8400557 - Clearwater Cardiovascular and Interventional Consultants | Safety Harbor | Florida |
| United States | 8400372 - Covenant Medical Center | Saginaw | Michigan |
| United States | 8400667 - Michigan Cardiovascular Institute | Saginaw | Michigan |
| United States | 8400840 - Washington University | Saint Louis | Missouri |
| United States | 8400369 - HealthEast Saint Joseph's Hospital | Saint Paul | Minnesota |
| United States | 8400752 - Regions Hospital | Saint Paul | Minnesota |
| United States | 8400704 - South Texas CV Consultants | San Antonio | Texas |
| United States | 8400694 - University of California San Diego Medical Center | San Diego | California |
| United States | 8400703 - San Diego Cardiac Center | San Diego | California |
| United States | 8400719 - V.A. San Diego Health Care System | San Diego | California |
| United States | 8400632 - North Ohio Heart Center | Sandusky | Ohio |
| United States | 8400686 - Intercoastal Medical Group | Sarasota | Florida |
| United States | 8401157 - Memorial Health University Medical Center | Savannah | Georgia |
| United States | 8400570 - Advanced Cardiology Specialists | Scranton | Pennsylvania |
| United States | 8400863 - Swedish Medical Center - Providence Campus | Seattle | Washington |
| United States | 8400890 - Revival Research Institute, LLC | Sherman | Texas |
| United States | 8401175 - Overton Brooks V.A. Medical Center | Shreveport | Louisiana |
| United States | 8400622 - Mercy Medical Research Institute | Springfield | Missouri |
| United States | 8401176 - Methodist Sugar Land Hospital | Sugar Land | Texas |
| United States | 8401163 - Washington Adventist Hospital | Takoma Park | Maryland |
| United States | 8400736 - Pepin Heart Institute | Tampa | Florida |
| United States | 8400700 - Mercy Saint Vincent Medical Center | Toledo | Ohio |
| United States | 8401164 - University of Toledo Medical Center | Toledo | Ohio |
| United States | 8400996 - Southern Arizona V.A. Healthcare System | Tucson | Arizona |
| United States | 8400664 - Oklahoma Heart Institute | Tulsa | Oklahoma |
| United States | 8400334 - Cardiology Associates of North Mississippi | Tupelo | Mississippi |
| United States | 8400521 - CAET Research | Tyler | Texas |
| United States | 8400726 - Westchester Medical Center | Valhalla | New York |
| United States | 8400909 - Ventura Clinical Trials | Ventura | California |
| United States | 8401189 - Cardiovascular Associates of the Delaware Valley | Vineland | New Jersey |
| United States | 8401128 - Hillcrest Family Health Center | Waco | Texas |
| United States | 8400891 - John Muir Medical Center Walnu | Walnut Creek | California |
| United States | 8401165 - Ascension Macomb-Oakland Hospital Warren Campus | Warren | Michigan |
| United States | 8400688 - George Washington University Medical Center | Washington | District of Columbia |
| United States | 8400779 - MedStar Clinical Research Center | Washington | District of Columbia |
| United States | 8400904 - Northeast Iowa Medical Education Foundation | Waterloo | Iowa |
| United States | 8400358 - Aspirus Research Institute | Wausau | Wisconsin |
| United States | 8401011 - Cardiology Partners Research Institute | Wellington | Florida |
| United States | 8400678 - The Iowa Clinic, PC | West Des Moines | Iowa |
| United States | 8400893 - Interventional Cardiology Medical Group | West Hills | California |
| United States | 8401179 - Reading Hospital | West Reading | Pennsylvania |
| United States | 8400742 - VMG Cardiology, Westwood | Westwood | New Jersey |
| United States | 8400515 - Wichita Falls Heart Clinic | Wichita Falls | Texas |
| United States | 8400794 - Geisinger Wyoming Valley | Wilkes-Barre | Pennsylvania |
| United States | 8400759 - Winchester Cardiology and Vascular Medicine | Winchester | Virginia |
| United States | 8400322 - Wake Forest University Health Sciences, Dept. of Cardiovascular Medicine | Winston-Salem | North Carolina |
| United States | 8400625 - Michigan Heart and Vascular Institute | Ypsilanti | Michigan |
| United States | 8400639 - Genesis Health Care System | Zanesville | Ohio |
| Lead Sponsor | Collaborator |
|---|---|
| CSL Behring |
United States, Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, Chile, Colombia, Croatia, Czechia, Denmark, Estonia, Finland, France, Georgia, Germany, Greece, Hong Kong, Hungary, Israel, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Malaysia, Mexico, Netherlands, New Zealand, Norway, Peru, Poland, Portugal, Romania, Russian Federation, Serbia, Singapore, Slovakia, South Africa, Spain, Sweden, Switzerland, Taiwan, Thailand, Turkey, Ukraine, United Kingdom,
Gibson CM, Duffy D, Korjian S, Bahit MC, Chi G, Alexander JH, Lincoff AM, Heise M, Tricoci P, Deckelbaum LI, Mears SJ, Nicolau JC, Lopes RD, Merkely B, Lewis BS, Cornel JH, Trebacz J, Parkhomenko A, Libby P, Sacks FM, Povsic TJ, Bonaca M, Goodman SG, Bhatt DL, Tendera M, Steg PG, Ridker PM, Aylward P, Kastelein JJP, Bode C, Mahaffey KW, Nicholls SJ, Pocock SJ, Mehran R, Harrington RA; AEGIS-II Committees and Investigators. Apolipoprotein A1 Infusions and Cardiovascular Outcomes after Acute Myocardial Infarction. N Engl J Med. 2024 May 2;390(17):1560-1571. doi: 10.1056/NEJMoa2400969. Epub 2024 Apr 6. — View Citation
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Time to first occurrence of any component of composite MACE (CV death, MI, or stroke ) | MACE [Major adverse cardiovascular event(s)][ (CV (cardiovascular)death, MI (Myocardial Infarction), or stroke) | Through 90 days | |
| Secondary | Key secondary outcome: Total number of hospitalizations for coronary, cerebral, or peripheral ischemia | Through 90 days | ||
| Secondary | Key secondary outcome: Time to first occurrence of CV death, MI, or stroke | Through 180 days | ||
| Secondary | Key secondary outcome: Time to first occurrence of CV death, MI, or stroke | Through 365 days | ||
| Secondary | Time to occurrence of CV death | Through 90 days | ||
| Secondary | Time to first occurrence of MI | Through 90 days | ||
| Secondary | Time to first occurrence of stroke | Through 90 days | ||
| Secondary | Time to occurrence of all-cause death | Through 365 days | ||
| Secondary | Number of subjects with adverse events | Through 90 days | ||
| Secondary | Percent of subjects with adverse events | Through 90 days | ||
| Secondary | Number of subjects with treatment-related adverse events | Through 365 days | ||
| Secondary | Percent of subjects with treatment-related adverse events | Through 365 days | ||
| Secondary | Number of subjects with serious adverse events | Through 365 days | ||
| Secondary | Percent of subjects with serious adverse events | Through 365 days | ||
| Secondary | Number of subjects with a shift in clinical laboratory assessments from baseline to worst post-treatment value according to normal range criteria (normal, high, or low) | Baseline and 29 days | ||
| Secondary | Percent of subjects with a shift in clinical laboratory assessments from baseline to worst post-treatment value according to normal range criteria (normal, high, or low) | Baseline and 29 days |
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