Long-term Follow-up of Health Related Quality of Life in Patients With Acute Coronary Syndrome

Acute Coronary Syndrome Clinical Trial

— EMMACE-3X  

Official title:

Long-term Follow-up of Health Related Quality of Life in Patients Hospitalised With Acute Coronary Syndrome: Evaluation of the Methods and Management of Acute Coronary Events (EMMACE)-3X

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT01955525
• Other study ID #: IRAS ID: 134080
• Status: Not yet recruiting
• Phase: N/A
• First received: September 28, 2013
• Last updated: October 4, 2013
• Start date: November 2013
• Est. completion date: November 2023

Study information

• Verified date: September 2013
• Source: University of Leeds
• Contact: Chris P Gale, BSc MBBS MRCP Ph.D M.Ed FESC
• Phone: +44113 343
• Email: c.p.gale[@]leeds.ac.uk
• Is FDA regulated: No
• Health authority: United Kingdom:National Institute for Health Research (NIHR)
• Study type: Observational [Patient Registry]

Clinical Trial Summary

This study is aiming to i)measure longterm health related quality of life (HRQL) outcomes of the EMMACE3 patients hospitalised with acute coronary syndromes (ACS) and evaluate possible associations with their cardiovascular profile and to ii) Linkage these data to multiple electronic healthcare records

Description:

Over the last few years the chance of dying from a heart attack in England and Wales has reduced dramatically. Even so, there remain huge differences in mortality between hospitals. For example, up to a third of patients with a heart attack who attend hospitals in England are more likely to die than would be expected. That is, the type of treatment and the risk of death depend upon where a patient lives and which hospital they attend. In part, the variation in death may be due to the services available at the hospital or to factors such as socioeconomic deprivation. It may also relate to other factors such as depression, cardiac rehabilitation, patient experience of hospital care and health quality of life.

Using statistical approaches that include measures of quality of life, we propose to examine data about heart attacks in England and investigate the 'postcode lottery of care'. This research is a long term followup that promote improved patient care. In doing so, different factors affecting cardiac rehabilitation will be highlighted and healthcare policy changed so that all patients will have an equal chance of surviving a heart attack.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 3500
• Est. completion date: November 2023
• Est. primary completion date: November 2023
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age>=18 years, both sexes, acute admission to hospital in England with an ACS, consented to participate in EMMACE3 study

Exclusion Criteria:

• Those in whom follow up would be inappropriate or impractical (for example patients in the terminal stages of an illness or requiring emergency treatment such that the gathering research data is not possible or appropriate.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Acute Coronary Syndrome
• Syndrome

Locations

Country	Name	City	State
United Kingdom	University of Leeds	Leeds	West Yorkshire

Sponsors (1)

Lead Sponsor	Collaborator
University of Leeds

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Health related quality of life	This research will therefore allow greater insights into the associations of patients and hospital characteristics with longerterm outcomes after ACS. It will identify good hospital practice and make recommendations for hospital care that will improve patient wellbeing.	10 years	No
Secondary	Mortality		10 years	No

External Links

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