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Colchicine for Acute Coronary Syndromes — COACS  

Acute Coronary Syndrome Clinical Trial

Official title:
Colchicine for Acute Coronary Syndromes. A Multicenter Double Blind Randomized Trial.

Clinical Trial Summary

Multicenter, double blind, randomized trial to assess the effect of low-dose colchicine (0.5mg/day) on overall mortality, new coronary syndromes, and ischemic stroke at 2 years after an acute coronary syndrome. The study hypothesis is that colchicine may reduce the specified combined endpoint from 16% to 7-8% at a 2-years follow-up.

Clinical Trial Description

Multicenter, double-blind randomized trial to evaluate the efficacy of low dose colchicine (0.5mg once daily for 2 years) to reduce the incidence of subsequent overall mortality, new acute coronary syndromes, and ischemic stroke in patients admitted for an acute coronary syndrome. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01906749
Study type Interventional
Source Maria Vittoria Hospital
Contact Massimo Imazio, MD
Phone +39011439
Email massimo_imazio@yahoo.it
Status Recruiting
Phase Phase 4
Start date June 2013
Completion date June 2016
View Details
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