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Abdominal Surgery clinical trials

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NCT ID: NCT04887922 Terminated - Abdominal Surgery Clinical Trials

Preoperative and Postoperative Incentive Spirometry in Patients Undergoing Major Abdominal Surgery

Start date: May 3, 2022
Phase: N/A
Study type: Interventional

The goal of this study is to determine the efficacy of incentive spirometry (IS) to improve pulmonary function in the preoperative and postoperative surgical setting. The investigators hypothesize that IS will improve pulmonary function for patients undergoing major abdominal surgery when controlling for protocol compliance. Additionally, the investigators hypothesize that a digital IS device enabled with a text message-based mobile health intervention will improve pulmonary pre-habilitation and rehabilitation, as well as postoperative compliance with the IS device.

NCT ID: NCT03706963 Terminated - Abdominal Surgery Clinical Trials

Remote Telemonitoring to Improve Prehabilitation and Surgical Outcomes of Patients Undergoing Elective Abdominal Surgery

Start date: January 15, 2019
Phase: N/A
Study type: Interventional

There is data confirming that simple tests of physical capability, such as the timed "get-up-and-go" test and the 6-minute walk test, correlate with surgical outcomes. It is reasonable to assume that preoperative telemonitoring, which allows for the tracking of more variables over a wider range of activities, could provide a significantly more accurate picture of a patient's physical fitness than a short one-time test performed in the clinic setting. Almost half of the patients who are readmitted at Washington University are readmitted for less than 4 days. The readmitted patients usually present with sepsis, are treated with antibiotics and percutaneous drainage, and are discharged home relatively quickly. Earlier identification of these patients, prior to the development of sepsis, would reduce the risks to the patient and allow for outpatient management.

NCT ID: NCT03684304 Terminated - Clinical trials for Pelvic Organ Prolapse

The Effect of Abdominal Binder Use on Postoperative Pain and Mobility in Patients Undergoing Pelvic Surgery

Start date: October 30, 2017
Phase: N/A
Study type: Interventional

To determine the effect of post-operative abdominal binder usage on total narcotic usage after undergoing surgery. To determine if abdominal binder usage results in decreased visual analog scale (VAS) pain scores and shorter time to first ambulation post operatively.

NCT ID: NCT00953940 Terminated - Abdominal Surgery Clinical Trials

Prevention of Perioperative Acute Renal Failure

Start date: June 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to measure the acute renal dysfunction on the first, second, seventh and twentieth days.

NCT ID: NCT00716833 Terminated - Pain Clinical Trials

Etoricoxibe - Preemptive and Postoperative Analgesia for Abdominal and Thoracic Surgery

EPPA
Start date: February 2006
Phase: Phase 3
Study type: Interventional

This randomised placebo controlled double-blinded bicentre study (phase III) was designed to evaluate the preemptive and postoperative analgetic impact of etoricoxibe in open abdominal and thoracic surgery. Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2). Therefore 120 patients (ASA-risk 1-2) with upcoming abdominal or thoracic surgery should be included into this study. Patients are randomly allocated to either the preemptive or the postoperative Etoricoxibe group. These two groups are divided each into two arms. Preemptive group patients get Etoricoxibe either twice (before and after surgery) or just a single preoperative dose. Postoperative group patients get placebo before surgery and either a drug application or a placebo again after surgery (so called 2x2 factorial study design). Cumulative use of morphine as assessed within first 48 hours after surgery is the primary trial outcome indicating the analgesic potency of Etoricoxibe. In addition, changes in patients level of sensibilisation will be measured with help of quantitative sensory testing (a standardised procedure) before and after surgery (secondary outcome). In addition pharmacogenetic testing will provide information about genetic aberrations (so called polymorphisms) of the patients enzymes that should be compared to the individual reaction regarding Etoricoxibe. The results will give hint about the analgesic impact of etoricoxibe in acute postoperative pain. There will be findings for preemptive analgesia and nerval processes. All this could lead to an improvement of postoperative pain relief while administrating preemptively a COX-2 selective inhibitor before surgery.

NCT ID: NCT00596778 Terminated - Abdominal Surgery Clinical Trials

Chest Physiotherapy on Immediate Postoperative in Patients Submitted to High Abdominal Surgery

Start date: February 2004
Phase: N/A
Study type: Interventional

Abdominal surgical procedures can increase risks of pulmonary complications.The aim of the study was to evaluate the benefits of an early intervention of chest physiotherapy during immediate post-operative in patients submitted to elective abdominal surgery.

NCT ID: NCT00587548 Terminated - Abdominal Surgery Clinical Trials

Intraoperative Gamma Probe Localization of the Ureter

Start date: January 2006
Phase: N/A
Study type: Interventional

This study is being done to find a different way to identify the ureters during an abdominal operation. During some operations, the operating physician must identify where the ureters are to prevent injury to them. Typically, the surgeon calls the urologist to thread a small scope with a camera into the urethra (where the urine comes out) to place a wire into each of the two ureters to locate them. Instead of this procedure, we will inject a small amount of a radioactive chemical dye (TC99-DTPA)through a vein in your arm. The ureters can then be detected by a hand held probe called the 'gamma probe.' The TC99-DTPA dye passes through the body and is excreted through the urine. The goal of this study is that this probe will alert the physician when it placed directly over the ureters since the TC99-DTPA dye will highlight the ureters as the flow of urine goes through them.