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Wounds and Injuries clinical trials

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NCT ID: NCT04459910 Completed - Ankle Injuries Clinical Trials

Medial and Lateral Combined Ligament Arthroscopic Repair for Multidirectional Ankle Instability: Case Series

Start date: July 1, 2019
Phase:
Study type: Observational

Abstract Introduction: The high prevalence of sprains in the population has provided a substantial number of patients with lateral instability of the ankle. The continuity of this condition can lead to the progressive loosening of the medial containment structures, generating a multidirectional rotational instability. The deltoid approach through the imbrication of its components has been proposed as a solution for these patients. The arthroscopic technique has been described as an alternative. Methods: This is a retrospective study with patients diagnosed with multidirectional instability and submitted to an ankle arthroscopy with medial repair (arthroscopic tensioning) and lateral (arthroscopic Brostrom) between January 2018 and January 2020. All patients will fill an epidemiological questionnaire and will be evaluated for pain and function according to the Visual Analogue Scale (VAS) and the American Orthopaedic Foot and Ankle Society Score (AOFAS) at 12 months (6-24 months) average of follow-up. Discussion: The combined medial and lateral arthroscopic repair may be an effective and safe alternative in the treatment of multidirectional instability. The inclusion of the deltoid complex and the low invasiveness of this technique can improve the clinical outcomes of these patients. Additional studies, with a prospective and comparative methodology are required to sustain this proposal. Design: Level IV. Retrospective case series. Keywords: ankle injuries; lateral ligament; collateral ligaments; joint instability

NCT ID: NCT04455490 Completed - Wound Healing Clinical Trials

Clinical Effect of Endoscopic Surgery for Delayed Wound Healing After Achilles Tendon Suture

Start date: March 18, 2020
Phase:
Study type: Observational

This study proposes endoscopic surgery for delayed wound healing after Achilles tendon suture which is a brand new treatment,and retrospectively analyzed the clinical data of 4 cases treated with this treatment. The analysis results of the clinical efficacy of the method can serve as a reference for clinical and surgical decision-making and prognosis assessment.

NCT ID: NCT04455373 Completed - Child Health Clinical Trials

Long-term Outcome in Pediatric Surgical Bypass Grafting After Traumatic Injury and Tumor Resection

Start date: January 1, 2002
Phase:
Study type: Observational

Introduction: Vascular bypass surgery in children differs significantly from adults. It is a rarely performed procedure in the setting of trauma and tumor surgery to facilitate limb salvage. Beside the technical challenges to reconstruct the small and spastic vessels, bypass grafting should not impede growth of the extremity. The primary aim of this study was to assess long-term outcome after pediatric bypass grafting, in a single academic center, focusing on potential effects on limb development. Methods: In this retrospective cohort analyses we included all pediatric patients undergoing vascular bypass grafting at the Medical University of Vienna between 2002-2017. All patients ≤ 18 years suffered a traumatic injury or underwent a tumor resection of the lower or upper limb, respectively. The youngest female patient was 0.4 years, the youngest male patient was 3.5 years.

NCT ID: NCT04453228 Completed - Skiing Injury Clinical Trials

Analysis of the Mass Skiers' Injury in a Large Ski Resort in Chongli, China

Start date: March 22, 2020
Phase:
Study type: Observational

This study takes the injury situation of a large ski resort in Chongli during the 2017-2018 and 2018-2019 snow seasons as an example, aiming to preliminarily understand the injury situation of mass skiing in ski resorts in China, and provide a basis for predicting the rapidly growing medical demand for treatment and treatment of ski injuries in the context of 2022 Winter Olympic Games.

NCT ID: NCT04436016 Completed - Myocardial Ischemia Clinical Trials

PeRiOperaTivE CardioproTection With Ivabradine in Non-cardiac Surgery

PROTECTIN
Start date: October 5, 2020
Phase: Phase 4
Study type: Interventional

Perioperative myocardial injury (PMI) after non-cardiac surgery (NCS), i.e. the elevation of postoperative troponin, occurs in nearly 20% of patients older than 45 years undergoing NCS and is independently and strongly associated with post-operative mortality (30-day mortality up to 10%). With over 300 million surgical interventions every year worldwide, PMI has a high clinical relevance on the health of the population. Heart rate (HR) is an independent and modifiable risk factor for PMI and death after non-cardiac surgery. Numerous studies showed that beta-blockers decrease myocardial ischemia after surgery in a heart-rate dependent manner, but this beneficial effect is surpassed by an increased incidence of perioperative hypotension and death. Currently, no single intervention is available to decrease the risk of perioperative cardiac complications. Ivabradine (IVA) is a negative chronotropic agent without significant effects on contractility or vascular tone and has been shown to improve outcomes in the setting of chronic and acute heart diseases. Rationale for pilot feasibility trial: the planned definitive large trial is a multicenter trial to investigate the efficacy of ivabradine to decrease perioperative myocardial injury. The intervention planned is complex and demands important resources. The investigators designed this pilot study to inform on the feasibility of the definitive large trial. This pilot study will also provide additional information that could help investigators improve the definitive large trial regarding recruitment, refinements to the study protocol and improving the participant's experience.

NCT ID: NCT04434820 Completed - Wound Dehiscence Clinical Trials

External Negative Pressure Dressing System vs. Traditional Wound Dressing for Cesarean Section Incision in Obese Women.

Start date: August 3, 2020
Phase: N/A
Study type: Interventional

Obesity is associated with increased cesarean section delivery rates and surgical site infections with associated increased post-operative morbidity, post-operative pain and length of hospital stay. Negative pressure wound therapy (NPWT) technology could be used as a prophylactic measure to reduce surgical site infections in obese women undergoing cesarean section by immediate postoperative application in clean-contaminated, closed surgical incisions.

NCT ID: NCT04431102 Completed - Pregnancy Clinical Trials

Pilates and the Pelvic Floor: A Quasi-experimental Study

Start date: November 5, 2018
Phase: N/A
Study type: Interventional

In this paper, it is postulates that in pregnant women, the practice of PM led by a qualified professional for a period of four weeks can reduce the incidence of pelvic floor dysfunction (PFD) by decreasing the number of birth injuries.

NCT ID: NCT04428970 Completed - Clinical trials for Traumatic Brain Injury

Intracranial Pressure (ICP) Monitoring Following Traumatic Brain Injury (TBI)

Start date: January 1, 2007
Phase:
Study type: Observational

The aim of this retrospective cohort study is to evaluate complications rates, indications, and the utility of follow-up imaging studies of ICP measurement in severe TBI patients.

NCT ID: NCT04426071 Completed - Stroke Clinical Trials

The Impact of a Societal Lockdown on Those With Spinal Cord and Brain Injuries

Start date: June 1, 2020
Phase:
Study type: Observational

Document and evaluate the impact of societal restrictions due to the pandemic on SCI- and ABI-related disability and functional impairments, and the resultant effects on psychological wellbeing, physical wellbeing and quality of life for those with SCI/ABI.

NCT ID: NCT04422769 Completed - Clinical trials for Spinal Cord Injuries

Needs of Persons With Spinal Cord Injury (SCI)

Start date: May 22, 2020
Phase:
Study type: Observational

Persons with spinal cord injury (PwSCI) are at a greater risk for major health conditions and poorer health outcomes than persons without spinal cord injury (SCI). They often experience a great deal of health needs both on a physiological level as well as a psychosocial level. PwSCI frequently require supports and services to be able to live independently within the community. These services and supports are sometimes difficult to access within the community when the country is operating under regular capacity, in current times with the global COVID-19 pandemic, the challenges for obtaining and accessing supports and services will become much greater. The proposed project aims to identify the specific needs during this time of crisis and to provide referrals and resources to ameliorate those needs by surveying PwSCI in the St. Louis region. The project also hopes to determine if these persons experience isolation during shelter at home orders. PwSCI, who the investigators serve or have served in the past, will be contacted via phone or e-mail once a month for six months and asked to complete a questionnaire that will allow the investigators to track the participant's needs during the COVID-19 pandemic.