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Type 2 Diabetes clinical trials

View clinical trials related to Type 2 Diabetes.

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NCT ID: NCT00252876 Terminated - Type 2 Diabetes Clinical Trials

GALLEX 1 - Long Term Extension Study in Patients With Type 2 Diabetes

Start date: March 2005
Phase: Phase 3
Study type: Interventional

This is a 107-week open-label, multi-center long-term extension study from GALLANT studies 2/22, 5, 7, 8 and 14 to monitor the safety and tolerability of oral tesaglitazar 1 mg in patients with type 2 diabetes during up to 104 weeks of treatment. The total duration, including treatment and follow-up, is 107 weeks.

NCT ID: NCT00252837 Terminated - Type 2 Diabetes Clinical Trials

GALLANT 22 Tesaglitazar vs. Placebo

Start date: April 2005
Phase: Phase 3
Study type: Interventional

This is a 24-week randomized, double-blind, parallel-group, multi-center, placebo-controlled study of tesaglitazar (0.5 and 1 mg) in patients with type 2 diabetes, not adequately controlled on diet and lifestyle advice alone during the run-in period. The study comprises a 6-week single-blind placebo run-in period, followed by 24-week treatment period and a 3-week follow-up period. The study design of GALLANT 2 is identical to GALLANT 22; the blinded study data from GALLANT 2 will be transferred to the GALLANT 22 database and will be analyzed together with the data from GALLANT 22 clinical study.

NCT ID: NCT00252772 Terminated - Type 2 Diabetes Clinical Trials

GALLANT 2 Tesaglitazar vs. Placebo

Start date: September 2004
Phase: Phase 3
Study type: Interventional

This is a 24-week randomized, double-blind, parallel-group, multi-center, placebo-controlled study of tesaglitazar (0.5 and 1 mg) in patients with type 2 diabetes, not adequately controlled on diet and lifestyle advice alone during the run-in period. The study comprises a 6-week single-blind placebo run-in period followed by 24-week treatment period and a 3-week follow-up period. The study design of GALLANT 2 is identical to GALLANT 22; the blinded study data from GALLANT 2 will be transferred to the GALLANT 22 database and will be analyzed together with the data from GALLANT 22 clinical study.

NCT ID: NCT00252694 Completed - Type 2 Diabetes Clinical Trials

DIabetic Retinopathy Candesartan Trials

DIRECT
Start date: August 2001
Phase: Phase 3
Study type: Interventional

The primary objective is to determine whether candesartan, compared to placebo reduces the progression of diabetic retinopathy in normoalbuminuric type 2 diabetic patients with retinopathy. The secondary objective is to determine whether candesartan, compared to placebo, reduces the incidence of clinically significant macular oedema (CSME) and/or proliferative diabetic retinopathy (PDR) and beneficially influences the rate change in urinary albumin excretion rate (UAER). This study is part of the DIRECT Programme also including a primary prevention study of diabetic retinopathy in type 1 diabetes and a secondary prevention study in type 1 diabetes. The primary objective for all three pooled studies is to determine whether candesartan, compared to placebo, reduces the incidence of microalbuminuria in type 1 and type 2 diabetic patients.

NCT ID: NCT00251953 Terminated - Type 2 Diabetes Clinical Trials

GALLANT 8 Tesaglitazar Add-on to Metformin

Start date: July 2004
Phase: Phase 3
Study type: Interventional

This is a 24-week randomized double-blind, parallel-group, multi-center, placebo-controlled study of tesaglitazar (0.5 mg and 1 mg) given as add-on therapy to metformin in patients with type 2 diabetes, not adequately controlled on optimized metformin treatment and on diet/lifestyle advice during the titration and run-in period. The study comprises a 2-week enrollment period, 6 week placebo metformin titration period, 2-week single-blind run-in period, followed by a 24-week double blind treatment period and a 3-week follow-up period

NCT ID: NCT00251940 Terminated - Type 2 Diabetes Clinical Trials

GALLANT 7 Tesaglitazar Add-on to Sulphonylurea

Start date: July 2004
Phase: Phase 3
Study type: Interventional

This is a 24-week randomized double-blind, parallel-group, multi-center, placebo-controlled study of tesaglitazar (0.5 mg and 1 mg) given as add-on therapy to sulphonylurea in patients with type 2 diabetes, not adequately controlled on optimized sulphonylurea treatment and on diet/lifestyle advice during the titration and run-in period. The study comprises a 2-week enrollment period, 6 week placebo metformin titration period, 2-week single-blind run-in period, followed by a 24-week double blind treatment period and a 3-week follow-up period

NCT ID: NCT00251680 Completed - Type 2 Diabetes Clinical Trials

Efficacy of Lapaquistat Acetate in Subjects Currently Treated With Lipid-Lowering Therapy.

Start date: October 2005
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine the efficacy of lapaquistat acetate, once daily (QD), taken with established lipid-lowering therapy in subjects with type 2 diabetes mellitus.

NCT ID: NCT00241085 Completed - Hypertension Clinical Trials

Effect of Valsartan on Proteinuria in Patients With Hypertension and Diabetes Mellitus

Start date: November 2002
Phase: Phase 4
Study type: Interventional

This is a study of whether valsartan affects levels of proteinuria in patients with type 2 diabetes and hypertension.

NCT ID: NCT00240370 Completed - Type 2 Diabetes Clinical Trials

A Study to Evaluate Combining Metformin With Muraglitazar or Pioglitazone in Type 2 Diabetics

Start date: October 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate if type 2 diabetics who have inadequate glycemic control on metformin alone, have a similar, or not inferior, glycemic response when treated with the combination of muraglitazar and metformin compared to pioglitazone and metformin.

NCT ID: NCT00239707 Completed - Type 2 Diabetes Clinical Trials

GIP: Glucose-dependent Insulinotropic Peptide

Start date: February 2003
Phase: Phase 1
Study type: Interventional

The purpose of this study is to test the safety of glucose-dependent insulinotropic peptide (GIP)/GIP Analog on people with Type 2 Diabetes.